| Literature DB >> 22220815 |
Francisco Velázquez1, Srikanth Venkatraman, Charles A Lesburg, José Duca, Stuart B Rosenblum, Joseph A Kozlowski, F George Njoroge.
Abstract
The synthesis of substituted 3,4-dihydrofuranoindoles is reported. These new indole compounds were used to synthesize potent HCV NS5B inhibitors. The binding mode of the dihydrofuranoindole-derived inhibitors was established via X-ray crystallographic studies.Entities:
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Year: 2012 PMID： 22220815 DOI： 10.1021/ol203177g
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005