Literature DB >> 22205746

Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors.

Judd F Hultquist1, Mawuena Binka, Rebecca S LaRue, Viviana Simon, Reuben S Harris.   

Abstract

HIV-1 requires the cellular transcription factor CBFβ to stabilize its accessory protein Vif and promote APOBEC3G degradation. Here, we demonstrate that both isoforms of CBFβ allow for increased steady-state levels of Vif, enhanced APOBEC3G degradation, and increased viral infectivity. This conserved functional interaction enhances the steady-state levels of Vif proteins from multiple HIV-1 subtypes and is required for the degradation of all human and rhesus Vif-sensitive APOBEC3 proteins by their respective lentiviral Vif proteins.

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Year:  2011        PMID： 22205746      PMCID： PMC3302251          DOI： 10.1128/JVI.06950-11

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  13 in total

1.  Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex.

Authors:  Xianghui Yu; Yunkai Yu; Bindong Liu; Kun Luo; Wei Kong; Panyong Mao; Xiao-Fang Yu
Journal:  Science       Date:  2003-10-16       Impact factor: 47.728

2.  Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function.

Authors:  Masayuki Kobayashi; Akifumi Takaori-Kondo; Yasuhiro Miyauchi; Kazuhiro Iwai; Takashi Uchiyama
Journal:  J Biol Chem       Date:  2005-03-21       Impact factor: 5.157

3.  Primate lentiviral virion infectivity factors are substrate receptors that assemble with cullin 5-E3 ligase through a HCCH motif to suppress APOBEC3G.

Authors:  Kun Luo; Zuoxiang Xiao; Elana Ehrlich; Yunkai Yu; Bindong Liu; Shu Zheng; Xiao-Fang Yu
Journal:  Proc Natl Acad Sci U S A       Date:  2005-08-02       Impact factor: 11.205

4.  Antiretroviral activity and Vif sensitivity of rhesus macaque APOBEC3 proteins.

Authors:  Cesar A Virgen; Theodora Hatziioannou
Journal:  J Virol       Date:  2007-10-17       Impact factor: 5.103

Review 5.  HIV-1 accessory proteins--ensuring viral survival in a hostile environment.

Authors:  Michael H Malim; Michael Emerman
Journal:  Cell Host Microbe       Date:  2008-06-12       Impact factor: 21.023

6.  Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.

Authors:  Stefanie Jäger; Dong Young Kim; Judd F Hultquist; Keisuke Shindo; Rebecca S LaRue; Eunju Kwon; Ming Li; Brett D Anderson; Linda Yen; David Stanley; Cathal Mahon; Joshua Kane; Kathy Franks-Skiba; Peter Cimermancic; Alma Burlingame; Andrej Sali; Charles S Craik; Reuben S Harris; John D Gross; Nevan J Krogan
Journal:  Nature       Date:  2011-12-21       Impact factor: 49.962

7.  Optimal translation initiation enables Vif-deficient human immunodeficiency virus type 1 to escape restriction by APOBEC3G.

Authors:  Guylaine Haché; Truus E M Abbink; Ben Berkhout; Reuben S Harris
Journal:  J Virol       Date:  2009-03-18       Impact factor: 5.103

8.  Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction.

Authors:  Eric W Refsland; Mark D Stenglein; Keisuke Shindo; John S Albin; William L Brown; Reuben S Harris
Journal:  Nucleic Acids Res       Date:  2010-03-22       Impact factor: 16.971

Review 9.  Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics.

Authors:  John S Albin; Reuben S Harris
Journal:  Expert Rev Mol Med       Date:  2010-01-22       Impact factor: 5.600

10.  Global trends in molecular epidemiology of HIV-1 during 2000-2007.

Authors:  Joris Hemelaar; Eleanor Gouws; Peter D Ghys; Saladin Osmanov
Journal:  AIDS       Date:  2011-03-13       Impact factor: 4.177
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  45 in total

1.  HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor β on genetically distinct surfaces.

Authors:  Judd F Hultquist; Rebecca M McDougle; Brett D Anderson; Reuben S Harris
Journal:  AIDS Res Hum Retroviruses       Date:  2012-08-13       Impact factor: 2.205

2.  Evolutionarily conserved pressure for the existence of distinct G2/M cell cycle arrest and A3H inactivation functions in HIV-1 Vif.

Authors:  Ke Zhao; Juan Du; Yajuan Rui; Wenwen Zheng; Jian Kang; Jingwei Hou; Kang Wang; Wenyan Zhang; Viviana A Simon; Xiao-Fang Yu
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

Review 3.  The Road Less Traveled: HIV's Use of Alternative Routes through Cellular Pathways.

Authors:  Ailie Marx; Akram Alian
Journal:  J Virol       Date:  2015-03-11       Impact factor: 5.103

4.  Differential requirements for HIV-1 Vif-mediated APOBEC3G degradation and RUNX1-mediated transcription by core binding factor beta.

Authors:  Juan Du; Ke Zhao; Yajuan Rui; Peng Li; Xiaohong Zhou; Wenyan Zhang; Xiao-Fang Yu
Journal:  J Virol       Date:  2012-11-21       Impact factor: 5.103

5.  The APOBEC3C crystal structure and the interface for HIV-1 Vif binding.

Authors:  Shingo Kitamura; Hirotaka Ode; Masaaki Nakashima; Mayumi Imahashi; Yuriko Naganawa; Teppei Kurosawa; Yoshiyuki Yokomaku; Takashi Yamane; Nobuhisa Watanabe; Atsuo Suzuki; Wataru Sugiura; Yasumasa Iwatani
Journal:  Nat Struct Mol Biol       Date:  2012-09-23       Impact factor: 15.369

6.  Core-binding factor subunit beta is not required for non-primate lentiviral Vif-mediated APOBEC3 degradation.

Authors:  Youwei Ai; Dantong Zhu; Cuihui Wang; Chao Su; Jian Ma; Jianzhang Ma; Xiaojun Wang
Journal:  J Virol       Date:  2014-08-13       Impact factor: 5.103

7.  Characterization of RNA binding and chaperoning activities of HIV-1 Vif protein. Importance of the C-terminal unstructured tail.

Authors:  Dona Sleiman; Serena Bernacchi; Santiago Xavier Guerrero; Franck Brachet; Valéry Larue; Jean-Christophe Paillart; Carine Tisne
Journal:  RNA Biol       Date:  2014-07-22       Impact factor: 4.652

8.  CBFβ enhances de novo protein biosynthesis of its binding partners HIV-1 Vif and RUNX1 and potentiates the Vif-induced degradation of APOBEC3G.

Authors:  Eri Miyagi; Sandra Kao; Venkat Yedavalli; Klaus Strebel
Journal:  J Virol       Date:  2014-02-12       Impact factor: 5.103

9.  Core-binding factor β increases the affinity between human Cullin 5 and HIV-1 Vif within an E3 ligase complex.

Authors:  Jason D Salter; Geoffrey M Lippa; Ivan A Belashov; Joseph E Wedekind
Journal:  Biochemistry       Date:  2012-10-25       Impact factor: 3.162

10.  Suppression of HIV-1 infection by APOBEC3 proteins in primary human CD4(+) T cells is associated with inhibition of processive reverse transcription as well as excessive cytidine deamination.

Authors:  Kieran Gillick; Darja Pollpeter; Prabhjeet Phalora; Eun-Young Kim; Steven M Wolinsky; Michael H Malim
Journal:  J Virol       Date:  2012-11-14       Impact factor: 5.103
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