Literature DB >> 22196714

Informing egg donors of the potential for embryonic research: a survey of consent forms from U.S. in vitro fertilization clinics.

Gerald Owen Schaefer1, Ninet Sinaii, Christine Grady.   

Abstract

OBJECTIVE: To understand whether and to what extent U.S. IVF clinics inform egg donors that resultant embryos initially intended to be implanted for reproductive purposes may in fact be used for research instead.
DESIGN: Four hundred seventy U.S. IVF clinics were asked to respond to a questionnaire and provide a copy of the egg donor consent form(s) used at the clinic.
SETTING: Four hundred seventy U.S. IVF clinics listed in a Centers for Disease Control and Prevention database; only forms from clinics that both accepted donor eggs and provided excess embryos for research were analyzed for content. PATIENT(S): Not applicable. INTERVENTION(S): Not applicable. MAIN OUTCOME MEASURE(S): Responses to the questionnaire, demographic data from a Centers for Disease Control and Prevention database, and the content of egg donor consent forms. RESULT(S): Of 222 U.S. IVF clinics that responded to our query, 100 clinics both accepted donor eggs and provided some excess embryos for research. We received 66 consent forms from these 100 clinics, which showed that although most egg donor consent forms inform donors that they will not have control over embryos resulting from their eggs, 30% inform them that some embryos may be used for research, and even fewer mention stem cell research. CONCLUSION(S): Egg donors in the United States, including some who may have a moral objection to research and stem cell research, are not being informed that embryos created with their donated eggs may in fact be used for these purposes. This can be corrected with the inclusion of succinct, nontechnical language in egg donor consent forms. Published by Elsevier Inc.

Entities:  

Mesh:

Year:  2011        PMID: 22196714      PMCID: PMC3556476          DOI: 10.1016/j.fertnstert.2011.11.035

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  7 in total

1.  A follow-up study with oocyte donors exploring their experiences, knowledge, and attitudes about the use of their oocytes and the outcome of the donation.

Authors:  A L Kalfoglou; G Geller
Journal:  Fertil Steril       Date:  2000-10       Impact factor: 7.329

2.  Informed consent and the use of gametes and embryos for research.

Authors: 
Journal:  Fertil Steril       Date:  2004-09       Impact factor: 7.329

3.  Ethics. The ISSCR guidelines for human embryonic stem cell research.

Authors:  George Q Daley; Lars Ahrlund Richter; Jonathan M Auerbach; Nissim Benvenisty; R Alta Charo; Grace Chen; Hong-Kui Deng; Lawrence S Goldstein; Kathy L Hudson; Insoo Hyun; Sung Chull Junn; Jane Love; Eng Hin Lee; Anne McLaren; Christine L Mummery; Norio Nakatsuji; Catherine Racowsky; Heather Rooke; Janet Rossant; Hans R Schöler; Jan Helge Solbakk; Patrick Taylor; Alan O Trounson; Irving L Weissman; Ian Wilmut; John Yu; Laurie Zoloth
Journal:  Science       Date:  2007-02-02       Impact factor: 47.728

4.  Informed consent and federal funding for stem cell research.

Authors:  Robert Streiffer
Journal:  Hastings Cent Rep       Date:  2008 May-Jun       Impact factor: 2.683

5.  1995 assisted reproductive technology success rates: national summary and fertility clinic report.

Authors:  I A Danel; Y T Green; G Walter
Journal:  J Womens Health       Date:  1998-04       Impact factor: 2.681

6.  Embryonic stem cell lines derived from human blastocysts.

Authors:  J A Thomson; J Itskovitz-Eldor; S S Shapiro; M A Waknitz; J J Swiergiel; V S Marshall; J M Jones
Journal:  Science       Date:  1998-11-06       Impact factor: 47.728

7.  Medicine. Consent from donors for embryo and stem cell research.

Authors:  Bernard Lo; Vicki Chou; Marcelle I Cedars; Elena Gates; Robert N Taylor; Richard M Wagner; Leslie Wolf; Keith R Yamamoto
Journal:  Science       Date:  2003-08-15       Impact factor: 47.728

  7 in total
  2 in total

1.  Germline Genome Editing Research: What Are Gamete Donors (Not) Informed About in Consent Forms?

Authors:  Emilia Niemiec; Heidi Carmen Howard
Journal:  CRISPR J       Date:  2020-02

2.  Dual consent? Donors' and recipients' views about involvement in decision-making on the use of embryos created by gamete donation in research.

Authors:  I Baía; C de Freitas; C Samorinha; V Provoost; S Silva
Journal:  BMC Med Ethics       Date:  2019-12-02       Impact factor: 2.652

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.