Literature DB >> 22194460

An epigenetic switch mediates bistable expression of the type 1 pilus genes in Streptococcus pneumoniae.

Alan Basset1, Keith H Turner, Elizabeth Boush, Sabina Sayeed, Simon L Dove, Richard Malley.   

Abstract

Expression of the pneumococcal type 1 pilus is bistable and positively regulated by the transcription factor RlrA. RlrA is also known to positively control its own expression. Here we present evidence that bistable expression of the type 1 pilus is mediated by the positive-feedback loop controlling rlrA expression.

Entities:  

Mesh：

Substances：

Year:  2011        PMID： 22194460      PMCID： PMC3294793          DOI： 10.1128/JB.06078-11

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  20 in total

Review 1.  Hysteresis vs. graded responses: the connections make all the difference.

Authors:  Alexander J Ninfa; Avraham E Mayo
Journal:  Sci STKE       Date:  2004-05-04

Review 2.  Phase and antigenic variation in bacteria.

Authors:  Marjan W van der Woude; Andreas J Bäumler
Journal:  Clin Microbiol Rev       Date:  2004-07       Impact factor: 26.132

3.  Substrate induction and glucose repression of maltose utilization by Streptomyces coelicolor A3(2) is controlled by malR, a member of the lacl-galR family of regulatory genes.

Authors:  G P van Wezel; J White; P Young; P W Postma; M J Bibb
Journal:  Mol Microbiol       Date:  1997-02       Impact factor: 3.501

4.  Expression of the type 1 pneumococcal pilus is bistable and negatively regulated by the structural component RrgA.

Authors:  Alan Basset; Keith H Turner; Elizabeth Boush; Sabina Sayeed; Simon L Dove; Richard Malley
Journal:  Infect Immun       Date:  2011-05-16       Impact factor: 3.441

5.  Streptococcus pneumoniae pilus subunits protect mice against lethal challenge.

Authors:  Claudia Gianfaldoni; Stefano Censini; Markus Hilleringmann; Monica Moschioni; Claudia Facciotti; Werner Pansegrau; Vega Masignani; Antonello Covacci; Rino Rappuoli; Michèle Anne Barocchi; Paolo Ruggiero
Journal:  Infect Immun       Date:  2006-12-04       Impact factor: 3.441

6.  An rpsL cassette, janus, for gene replacement through negative selection in Streptococcus pneumoniae.

Authors:  C K Sung; H Li; J P Claverys; D A Morrison
Journal:  Appl Environ Microbiol       Date:  2001-11       Impact factor: 4.792

7.  MgrA, an orthologue of Mga, Acts as a transcriptional repressor of the genes within the rlrA pathogenicity islet in Streptococcus pneumoniae.

Authors:  Carolyn Hemsley; Elizabeth Joyce; David L Hava; Amita Kawale; Andrew Camilli
Journal:  J Bacteriol       Date:  2003-11       Impact factor: 3.490

8.  A pneumococcal pilus influences virulence and host inflammatory responses.

Authors:  M A Barocchi; J Ries; X Zogaj; C Hemsley; B Albiger; A Kanth; S Dahlberg; J Fernebro; M Moschioni; V Masignani; K Hultenby; A R Taddei; K Beiter; F Wartha; A von Euler; A Covacci; D W Holden; S Normark; R Rappuoli; B Henriques-Normark
Journal:  Proc Natl Acad Sci U S A       Date:  2006-02-15       Impact factor: 11.205

9.  Association of the pneumococcal pilus with certain capsular serotypes but not with increased virulence.

Authors:  Alan Basset; Krzysztof Trzcinski; Christina Hermos; Katherine L O'Brien; Raymond Reid; Mathuram Santosham; Alexander J McAdam; Marc Lipsitch; Richard Malley
Journal:  J Clin Microbiol       Date:  2007-03-28       Impact factor: 5.948

10.  Transcriptional regulation in the Streptococcus pneumoniae rlrA pathogenicity islet by RlrA.

Authors:  David L Hava; Carolyn J Hemsley; Andrew Camilli
Journal:  J Bacteriol       Date:  2003-01       Impact factor: 3.490
View more
  8 in total

1.  The Pneumococcal Type 1 Pilus Genes Are Thermoregulated and Are Repressed by a Member of the Snf2 Protein Family.

Authors:  Alan Basset; Muriel Herd; Raecliffe Daly; Simon L Dove; Richard Malley
Journal:  J Bacteriol       Date:  2017-07-11       Impact factor: 3.490

2.  Effect of nonheme iron-containing ferritin Dpr in the stress response and virulence of pneumococci.

Authors:  Chun-Zhen Hua; Angela Howard; Richard Malley; Ying-Jie Lu
Journal:  Infect Immun       Date:  2014-07-07       Impact factor: 3.441

3.  Toll-like receptor (TLR) 2 mediates inflammatory responses to oligomerized RrgA pneumococcal pilus type 1 protein.

Authors:  Alan Basset; Fan Zhang; Cyril Benes; Sabina Sayeed; Muriel Herd; Claudette Thompson; Douglas T Golenbock; Andrew Camilli; Richard Malley
Journal:  J Biol Chem       Date:  2012-12-11       Impact factor: 5.157

Review 4.  Toxin-antitoxin genes of the Gram-positive pathogen Streptococcus pneumoniae: so few and yet so many.

Authors:  Wai Ting Chan; Inma Moreno-Córdoba; Chew Chieng Yeo; Manuel Espinosa
Journal:  Microbiol Mol Biol Rev       Date:  2012-12       Impact factor: 11.056

5.  Single cell stochastic regulation of pilus phase variation by an attenuation-like mechanism.

Authors:  Camille Danne; Sarah Dubrac; Patrick Trieu-Cuot; Shaynoor Dramsi
Journal:  PLoS Pathog       Date:  2014-01-16       Impact factor: 6.823

Review 6.  Novel Molecular Insights about Lactobacillar Sortase-Dependent Piliation.

Authors:  Ingemar von Ossowski
Journal:  Int J Mol Sci       Date:  2017-07-18       Impact factor: 5.923

7.  Molecular characterization of Streptococcus pneumoniae, particularly serotype19A/ST320, which emerged in Krasnoyarsk, Russia.

Authors:  Irina N Protasova; Tsai-Wen Wan; Natalya V Bakhareva; Wei-Chun Hung; Wataru Higuchi; Yasuhisa Iwao; Tatyana A Yelistratova; Natalya A Ilyenkova; Yelena S Sokolovskaya; Galina P Martynova; Ivan V Reva; Galina V Reva; Sergey V Sidorenko; Lee-Jene Teng; Olga V Peryanova; Alla B Salmina; Tatsuo Yamamoto
Journal:  Microbiol Immunol       Date:  2017-09       Impact factor: 1.955

Review 8.  Streptococcus pneumoniae Type 1 Pilus - A Multifunctional Tool for Optimized Host Interaction.

Authors:  Stefan Ness; Markus Hilleringmann
Journal:  Front Microbiol       Date:  2021-02-09       Impact factor: 5.640
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.