Literature DB >> 22192632

The hematopoietic cell transplantation comorbidity index is a predictor of early death and survival in adult acute myeloid leukemia patients.

Aleksandar Savic1, Vanja Kvrgic, Nebojsa Rajic, Ivana Urosevic, Dragan Kovacevic, Ivanka Percic, Stevan Popovic.   

Abstract

The hematopoietic cell transplantation comorbidity index (HCT-CI) is predictive of early death and survival in elderly patients with acute myeloid leukemia (AML). The aim of this study was to determine the prognostic role of the HCT-CI for early death and survival in adult AML patients. In the single-center retrospective study, we analyzed the outcome of 233 adult AML patients. The results indicated that the HCT-CI score is an independent predictor of early death in entire cohort of adult patients with AML. In subgroup analysis, HCT-CI is an independent predictor for early death in elderly patients but not in patients younger than 60 years. A high HCT-CI score predicts shorter survival in adult patients with AML.
Copyright © 2011 Elsevier Ltd. All rights reserved.

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Year:  2011        PMID： 22192632     DOI： 10.1016/j.leukres.2011.11.021

Source DB:  PubMed          Journal:  Leuk Res        ISSN： 0145-2126            Impact factor:   3.156


  14 in total

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