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Literature DB >> 22191920

Depth profiling of photothermal compound concentrations using phase sensitive optical coherence tomography.

Guangying Guan¹, Roberto Reif, Zhihong Huang, Ruikang K Wang.

Abstract

A model that describes the concentration of photothermal (light-to-heat converters) compounds as a function of depth in a turbid medium is developed. The system consists of a pump laser (808 nm modulated at 400 Hz), which heats a photothermal compound, and a phase sensitive spectral domain optical coherence tomography system, which detects the changes in the optical path length of the sample induced by the temperature increase. The model is theoretically derived and the coefficients are empirically determined using solid homogeneous gel phantoms. The model is validated by reconstructing the concentration of a photothermal compound in thick single and double layer solid phantoms.

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Year: 2011 PMID： 22191920 PMCID： PMC3247934 DOI： 10.1117/1.3659211

Source DB: PubMed Journal: J Biomed Opt ISSN： 1083-3668 Impact factor: 3.170

31 in total

1. Measurement of optical path length change following pulsed laser irradiation using differential phase optical coherence tomography.

Authors: Jihoon Kim; Junghwan Oh; Thomas E Milner
Journal: J Biomed Opt Date: 2006 Jul-Aug Impact factor: 3.170

2. Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography.

Authors: Z Chen; T E Milner; S Srinivas; X Wang; A Malekafzali; M J van Gemert; J S Nelson
Journal: Opt Lett Date: 1997-07-15 Impact factor: 3.776

3. Real-time phase-resolved functional optical coherence tomography by use of optical Hilbert transformation.

Authors: Yonghua Zhao; Zhongping Chen; Zhihua Ding; Hongwu Ren; J Stuart Nelson
Journal: Opt Lett Date: 2002-01-15 Impact factor: 3.776

4. In vivo quantification of chromophore concentration using fluorescence differential path length spectroscopy.

Authors: Bastiaan Kruijt; Slavka Kascakova; Henriette S de Bruijn; Angelique van der Ploeg-van den Heuvel; Henricus J C M Sterenborg; Dominic J Robinson; Arjen Amelink
Journal: J Biomed Opt Date: 2009 May-Jun Impact factor: 3.170

5. Three-dimensional high-resolution imaging of gold nanorods uptake in sentinel lymph nodes.

Authors: Yeongri Jung; Roberto Reif; Yaguang Zeng; Ruikang K Wang
Journal: Nano Lett Date: 2011-06-17 Impact factor: 11.189

6. Photothermal optical coherence tomography in ex vivo human breast tissues using gold nanoshells.

Authors: Chao Zhou; Tsung-Han Tsai; Desmond C Adler; Hsiang-Chieh Lee; David W Cohen; Amy Mondelblatt; Yihong Wang; James L Connolly; James G Fujimoto
Journal: Opt Lett Date: 2010-03-01 Impact factor: 3.776

7. Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy.

Authors: Timothy C Zhu; Jarod C Finlay; Stephen M Hahn
Journal: J Photochem Photobiol B Date: 2004-12-02 Impact factor: 6.252

8. Plasmon resonance coupling of metal nanoparticles for molecular imaging of carcinogenesis in vivo.

Authors: Jesse Aaron; Nitin Nitin; Kort Travis; Sonia Kumar; Tom Collier; Sun Young Park; Miguel José-Yacamán; Lezlee Coghlan; Michele Follen; Rebecca Richards-Kortum; Konstantin Sokolov
Journal: J Biomed Opt Date: 2007 May-Jun Impact factor: 3.170

9. Optical method for real-time monitoring of drug concentrations facilitates the development of novel methods for drug delivery to brain tissue.

Authors: Roberto Reif; Mei Wang; Shailendra Joshi; Ousama A'Amar; Irving J Bigio
Journal: J Biomed Opt Date: 2007 May-Jun Impact factor: 3.170

10. Experimental and theoretical studies of light-to-heat conversion and collective heating effects in metal nanoparticle solutions.

Authors: Hugh H Richardson; Michael T Carlson; Peter J Tandler; Pedro Hernandez; Alexander O Govorov
Journal: Nano Lett Date: 2009-03 Impact factor: 11.189

9 in total

Depth profiling of photothermal compound concentrations using phase sensitive optical coherence tomography.

1. Measurement of optical path length change following pulsed laser irradiation using differential phase optical coherence tomography.

2. Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography.

3. Real-time phase-resolved functional optical coherence tomography by use of optical Hilbert transformation.

4. In vivo quantification of chromophore concentration using fluorescence differential path length spectroscopy.

5. Three-dimensional high-resolution imaging of gold nanorods uptake in sentinel lymph nodes.

6. Photothermal optical coherence tomography in ex vivo human breast tissues using gold nanoshells.

7. Determination of the distribution of light, optical properties, drug concentration, and tissue oxygenation in-vivo in human prostate during motexafin lutetium-mediated photodynamic therapy.

8. Plasmon resonance coupling of metal nanoparticles for molecular imaging of carcinogenesis in vivo.

9. Optical method for real-time monitoring of drug concentrations facilitates the development of novel methods for drug delivery to brain tissue.

10. Experimental and theoretical studies of light-to-heat conversion and collective heating effects in metal nanoparticle solutions.

1. In vivo photothermal optical coherence tomography for non-invasive imaging of endogenous absorption agents.

2. Molecular Imaging in Optical Coherence Tomography.

3. Depth-resolved analytical model and correction algorithm for photothermal optical coherence tomography.

4. Photothermal optical lock-in optical coherence tomography for in vivo imaging.

5. In vivo imaging of nanoparticle delivery and tumor microvasculature with multimodal optical coherence tomography.

6. Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography.

7. In vivo photothermal optical coherence tomography of gold nanorod contrast agents.

8. Loose powder detection and surface characterization in selective laser sintering via optical coherence tomography.

9. In vivo photothermal optical coherence tomography of endogenous and exogenous contrast agents in the eye.