BACKGROUND: Hypocalcemia is the most common postoperative complication after total thyroidectomy. The aim of this prospective study was to determine biochemical parameters in the early postoperative period that could identify patients with significantly increased risk of symptomatic hypocalcemia development. METHODS: The study included 100 individuals undergoing total thyroidectomy from January to May 2009. In all patients PTH, calcium, inorganic phosphate, magnesium, and albumin levels were measured immediately preoperatively, 30 minutes postoperatively and every morning for the following five days. RESULTS: Clinically significant hypocalcemia was observed in 19% of all cases. Fall of the iPTH values by more than 88% from preoperative values, 30 min after completion of the surgery, showed 100% sensitivity and 100% specificity for the occurrence of symptomatic hypocalcemia. CONCLUSIONS: According to our results immediate postoperative measurement of the iPTH may be considered as a useful method to predict with high certainty which patients will need calcium supplementation, and to separate them from patients who can be safely and early discharged.
BACKGROUND:Hypocalcemia is the most common postoperative complication after total thyroidectomy. The aim of this prospective study was to determine biochemical parameters in the early postoperative period that could identify patients with significantly increased risk of symptomatic hypocalcemia development. METHODS: The study included 100 individuals undergoing total thyroidectomy from January to May 2009. In all patientsPTH, calcium, inorganic phosphate, magnesium, and albumin levels were measured immediately preoperatively, 30 minutes postoperatively and every morning for the following five days. RESULTS: Clinically significant hypocalcemia was observed in 19% of all cases. Fall of the iPTH values by more than 88% from preoperative values, 30 min after completion of the surgery, showed 100% sensitivity and 100% specificity for the occurrence of symptomatic hypocalcemia. CONCLUSIONS: According to our results immediate postoperative measurement of the iPTH may be considered as a useful method to predict with high certainty which patients will need calcium supplementation, and to separate them from patients who can be safely and early discharged.
Authors: H Aydin; S Ferahman; S Abdullayev; N A Sahbaz; A C Dural; D Guzey; C Akarsu; M Karabulut Journal: Acta Endocrinol (Buchar) Date: 2021 Apr-Jun Impact factor: 0.877
Authors: Sara Salehi Hammerstad; Ingrid Norheim; Trond Paulsen; Lise Marit Amlie; Erik Fink Eriksen Journal: World J Surg Date: 2013-02 Impact factor: 3.352
Authors: Kathrin Nagel; Anne Hendricks; Christina Lenschow; Michael Meir; Stefanie Hahner; Martin Fassnacht; Armin Wiegering; Christoph-Thomas Germer; Nicolas Schlegel Journal: BJS Open Date: 2022-09-02