Literature DB >> 22185627

Organometallic cages as vehicles for intracellular release of photosensitizers.

Frédéric Schmitt1, Julien Freudenreich, Nicolas P E Barry, Lucienne Juillerat-Jeanneret, Georg Süss-Fink, Bruno Therrien.   

Abstract

Water-soluble metalla-cages were used to deliver hydrophobic porphin molecules to cancer cells. After internalization, the photosensitizer was photoactivated, significantly increasing the cytotoxicity in cells. During the transport, the photosensitizer remains nonreactive to light, offering a new strategy to tackle overall photosensitization, a limitation often encountered in photodynamic therapy.
© 2011 American Chemical Society

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Year:  2011        PMID： 22185627     DOI： 10.1021/ja207784t

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  25 in total

1.  Spontaneous Formation of a Cross-Linked Supramolecular Polymer Both in the Solid State and in Solution, Driven by Platinum(II) Metallacycle-Based Host-Guest Interactions.

Authors:  Bingbing Shi; Yuezhou Liu; Huangtianzhi Zhu; Ryan T Vanderlinden; Liqing Shangguan; Ruidong Ni; Koushik Acharyya; Jian-Hong Tang; Zhixuan Zhou; Xiaopeng Li; Feihe Huang; Peter J Stang
Journal:  J Am Chem Soc       Date:  2019-04-12       Impact factor: 15.419

2.  Self-Healing Heterometallic Supramolecular Polymers Constructed by Hierarchical Assembly of Triply Orthogonal Interactions with Tunable Photophysical Properties.

Authors:  Qian Zhang; Danting Tang; Jinjin Zhang; Ruidong Ni; Luonan Xu; Tian He; Xiongjie Lin; Xiaopeng Li; Huayu Qiu; Shouchun Yin; Peter J Stang
Journal:  J Am Chem Soc       Date:  2019-10-28       Impact factor: 15.419

3.  Mechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage.

Authors:  Yao-Rong Zheng; Kogularamanan Suntharalingam; Peter M Bruno; Wei Lin; Weixue Wang; Michael T Hemann; Stephen J Lippard
Journal:  Inorganica Chim Acta       Date:  2016-03-25       Impact factor: 2.545

4.  Cucurbit[7]uril Enables Multi-Stimuli-Responsive Release from the Self-Assembled Hydrophobic Phase of a Metal Organic Polyhedron.

Authors:  Soumen K Samanta; Jeffrey Quigley; Brittany Vinciguerra; Volker Briken; Lyle Isaacs
Journal:  J Am Chem Soc       Date:  2017-06-23       Impact factor: 15.419

5.  Design and Applications of Water-Soluble Coordination Cages.

Authors:  Edmundo G Percástegui; Tanya K Ronson; Jonathan R Nitschke
Journal:  Chem Rev       Date:  2020-11-25       Impact factor: 60.622

Review 6.  Biomedically Relevant Self-Assembled Metallacycles and Metallacages.

Authors:  Hajar Sepehrpour; Wenxin Fu; Yan Sun; Peter J Stang
Journal:  J Am Chem Soc       Date:  2019-08-29       Impact factor: 15.419

Review 7.  The development of anticancer ruthenium(ii) complexes: from single molecule compounds to nanomaterials.

Authors:  Leli Zeng; Pranav Gupta; Yanglu Chen; Enju Wang; Liangnian Ji; Hui Chao; Zhe-Sheng Chen
Journal:  Chem Soc Rev       Date:  2017-10-02       Impact factor: 54.564

8.  Anticancer Activity of Self-Assembled Molecular Rectangles via Arene-Ruthenium Acceptors and a New Unsymmetrical Amide Ligand.

Authors:  Anurag Mishra; Hyunji Jung; Jeong Woo Park; Hong Kyeung Kim; Hyunuk Kim; Peter J Stang; Ki-Whan Chi
Journal:  Organometallics       Date:  2012-04-13       Impact factor: 3.876

9.  Orthogonal self-assembly of an organoplatinum(II) metallacycle and cucurbit[8]uril that delivers curcumin to cancer cells.

Authors:  Sougata Datta; Santosh K Misra; Manik Lal Saha; Nabajit Lahiri; Janis Louie; Dipanjan Pan; Peter J Stang
Journal:  Proc Natl Acad Sci U S A       Date:  2018-07-23       Impact factor: 11.205

10.  Modular Metal-Organic Polyhedra Superassembly: From Molecular-Level Design to Targeted Drug Delivery.

Authors:  Wei Zhu; Jimin Guo; Yi Ju; Rita E Serda; Jonas G Croissant; Jin Shang; Eric Coker; Jacob Ongudi Agola; Qi-Zhi Zhong; Yuan Ping; Frank Caruso; C Jeffrey Brinker
Journal:  Adv Mater       Date:  2019-01-31       Impact factor: 30.849
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