Literature DB >> 221849

Effects of superoxide radicals on transport (Na + K) adenosine triphosphatase and protection by superoxide dismutase.

T D Hexum, R Fried.   

Abstract

Membrane (Na +K)ATPase isolated from rat brain was preincubated in a medium in which superoxide radicals were generated enzymatically. Exposure to superoxide radicals caused an irreversible inactivation, which could be prevented by further addition of superoxide dismutase. (Na + K)ATPase was also protected by addition of allopurinol, a xanthine oxidase inhibitor, during preincubation. The K-activated nitrophenylphosphatase associated with (Na + K)ATPase was also found to be inactivated by preincubation with superoxide radicals, which could be prevented by superoxide dismutase.

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Year:  1979        PMID: 221849     DOI: 10.1007/bf00963833

Source DB:  PubMed          Journal:  Neurochem Res        ISSN: 0364-3190            Impact factor:   3.996


  20 in total

1.  The sodium-potassium adenosine triphosphatase: pharmacological, physiological and biochemical aspects.

Authors:  A Schwartz; G E Lindenmayer; J C Allen
Journal:  Pharmacol Rev       Date:  1975-03       Impact factor: 25.468

2.  Effect of ionic strength on the activity of bovine superoxide dismutase.

Authors:  A Rigo; P Viglino; G Rotilio; R Tomat
Journal:  FEBS Lett       Date:  1975-01-15       Impact factor: 4.124

3.  Ascorbic acid--a naturally occurring mediator of lipid peroxide formation in rat brain.

Authors:  O P Sharma; C R Krishna Murti
Journal:  J Neurochem       Date:  1976-07       Impact factor: 5.372

Review 4.  On the brain ascorbic acid and its importance in metabolism of biogenic amines.

Authors:  N Subramanian
Journal:  Life Sci       Date:  1977-05-01       Impact factor: 5.037

5.  Biological protection by superoxide dismutase.

Authors:  F Lavelle; A M Michelson; L Dimitrijevic
Journal:  Biochem Biophys Res Commun       Date:  1973-11-16       Impact factor: 3.575

6.  The effect of sulphydryl-blocking reagents and of urea on the (Na+ + K+)-activated enzyme system.

Authors:  J C Skou; C Hilberg
Journal:  Biochim Biophys Acta       Date:  1965-11-22

7.  Biological role of xanthine oxidase and tetrazolium-reductase inhibitor.

Authors:  R Fried; L W Fried; D R Babin
Journal:  Eur J Biochem       Date:  1973-03-15

8.  The inhibition of reduction of tetrazolium by a protein liver.

Authors:  R Fried; L W Fried; D Babin
Journal:  Eur J Biochem       Date:  1970-11

9.  The mechanism of the oxidation of ascorbate and MN2+ by chloroplasts. The role of the radical superoxide.

Authors:  B L Epel; J Neumann
Journal:  Biochim Biophys Acta       Date:  1973-12-14

10.  6-Hydroxydopamine: evidence for superoxide radical as an oxidative intermediate.

Authors:  R E Heikkila; G Cohen
Journal:  Science       Date:  1973-08-03       Impact factor: 47.728

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  14 in total

1.  Na+,K+-ATPase in developing fetal guinea pig brain and the effect of maternal hypoxia.

Authors:  O P Mishra; M Delivoria-Papadopoulos
Journal:  Neurochem Res       Date:  1988-08       Impact factor: 3.996

Review 2.  Role of superoxide dismutase in modification of radiation injury.

Authors:  A Petkau
Journal:  Br J Cancer Suppl       Date:  1987-06

3.  Lipid peroxidation as the mechanism of modification of the affinity of the Na+, K+-ATPase active sites for ATP, K+, Na+, and strophanthidin in vitro.

Authors:  O P Mishra; M Delivoria-Papadopoulos; G Cahillane; L C Wagerle
Journal:  Neurochem Res       Date:  1989-09       Impact factor: 3.996

4.  Disturbance of plasmalemmal astrocytic assemblies in focal and selective cerebral ischemia.

Authors:  P Cuevas; J A Gutierrez Diaz; M Dujovny; F G Diaz; J I Ausman
Journal:  Anat Embryol (Berl)       Date:  1985

5.  Lipid peroxidation as the mechanism of modification of brain 5'-nucleotidase activity in vitro.

Authors:  O P Mishra; M Delivoria-Papadopoulos; G Cahillane; L C Wagerle
Journal:  Neurochem Res       Date:  1990-03       Impact factor: 3.996

6.  Superoxide dismutase activity in rat brain during acute and chronic alcohol intoxication.

Authors:  M Ledig; J R M'Paria; P Mandel
Journal:  Neurochem Res       Date:  1981-04       Impact factor: 3.996

7.  Arachidonic acid-induced swelling in incubated rat brain cortical slices. Effect of bovine serum albumin.

Authors:  P H Chan; R A Fishman; J L Lee; S C Quan
Journal:  Neurochem Res       Date:  1980-06       Impact factor: 3.996

8.  Concurrent measurement of (Na+, K+)-ATPase activity and lipid peroxides in rat brain following reversible global ischemia.

Authors:  W J Goldberg; B D Watson; R Busto; H Kurchner; M Santiso; M D Ginsberg
Journal:  Neurochem Res       Date:  1984-12       Impact factor: 3.996

9.  N-acetylcysteine ameliorates carbofuran-induced alterations in lipid composition and activity of membrane bound enzymes.

Authors:  Amit Kamboj; Ravi Kiran; Rajat Sandhir
Journal:  Mol Cell Biochem       Date:  2006-02-22       Impact factor: 3.396

10.  Effects of alpha-phenyl-N-tert-butyl nitrone (PBN)on brain cell membrane function and energy metabolism during transient global cerebral hypoxia-ischemia and reoxygenation-reperfusion in newborn piglets.

Authors:  Chang Won Choi; Jong Hee Hwang; Yun Sil Chang; Son Moon Shin; Won Soon Park; Munhyang Lee
Journal:  J Korean Med Sci       Date:  2004-06       Impact factor: 2.153

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