| Literature DB >> 22183933 |
Piyush Banker1, Smitha Sonni, Ilya Kister, John P Loh, Yvonne W Lui.
Abstract
AQP4 water channels are thought to be the target of autoimmune attack in neuromyelitis optica-spectrum disorders (NMOsd). AQP4 are highly expressed on ventricular ependyma. The objective of this study was to describe a novel pattern of linear, 'pencil-thin' enhancement of ventricular ependyma in NMOsd. We report two NMOsd patients with pencil-thin ependymal enhancement along the frontal and occipital horns of lateral ventricles. Differential diagnosis of ependymal enhancement should include NMOsd alongside with infectious and neoplastic etiologies. Pencil-thin ependymal enhancement may be a helpful radiological marker of NMOsd that can be used to differentiate this condition from multiple sclerosis.Entities:
Mesh:
Year: 2011 PMID: 22183933 DOI: 10.1177/1352458511431730
Source DB: PubMed Journal: Mult Scler ISSN: 1352-4585 Impact factor: 6.312