An efficient and convenient access to 1-substituted indazol-3-ones 2 has been achieved throughout the intramolecular C-N bond formations of 2-chloro-benzoic acid-N'-aryl and alkyl-hydrazides employing 0.5 mol% of cuprous (I) iodide and 20 mol% of L-proline as catalyst precursors under mild conditions in moderate to excellent yields.
An efficient and convenient access to 1-substituted indazol-3-ones 2 has been achieved throughout the intramolecular C-n class="Chemical">N bond formations of 2-chloro-benzoic acid-N'-aryl and alkyl-hydrazides employing 0.5 mol% of cuprous (I) iodide and 20 mol% of L-proline as catalyst precursors under mild conditions in moderate to excellent yields.
Authors: Ju Young Kang; Suho Kim; Junghyea Moon; Eunjae Chung; Jaeyoung Kim; So Young Kyung; Hyung Sik Kim; Neeraj Kumar Mishra; In Su Kim Journal: ACS Omega Date: 2022-04-21