Debraj Mukherjee1, Chirag G Patil. 1. Department of Neurosurgery, Maxine Dunitz Neurosurgical Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Abstract
OBJECTIVE: Stroke remains one of the most devastating of all neurological diseases, often causing death or gross physical impairment or disability. As numerous countries throughout the world undergo the epidemiological transition of diseases, trends in the prevalence of stroke have dramatically changed. METHODS: All major international epidemiological articles published during the past 20 years addressing the global burden of stroke were reviewed. A focus was placed upon better defining current and future trends in surveillance, incidence, burden of disease, mortality, and costs associated with stroke internationally. RESULTS: Despite the fact that various surveillance systems are used to identify stroke and its sequela around the world, it is clear that stroke remains one of the top causes of mortality and disability-adjusted life-years (DALYs) lost globally. Concerning trends include the increase of stroke mortality and lost DALYs in low- and middle-income countries. The global economic impact of stroke may be dire if effective preventive measures are not implemented to help decrease the burden of this disease. CONCLUSION: The global burden of stroke is high, inclusive of increasing incidence, mortality, DALYs, and economic impact, particularly in low- and middle-income countries. The implementation of better surveillance systems and prevention programs are needed to help track current trends as well as to curb the projected exponential increase in stroke worldwide.
OBJECTIVE:Stroke remains one of the most devastating of all neurological diseases, often causing death or gross physical impairment or disability. As numerous countries throughout the world undergo the epidemiological transition of diseases, trends in the prevalence of stroke have dramatically changed. METHODS: All major international epidemiological articles published during the past 20 years addressing the global burden of stroke were reviewed. A focus was placed upon better defining current and future trends in surveillance, incidence, burden of disease, mortality, and costs associated with stroke internationally. RESULTS: Despite the fact that various surveillance systems are used to identify stroke and its sequela around the world, it is clear that stroke remains one of the top causes of mortality and disability-adjusted life-years (DALYs) lost globally. Concerning trends include the increase of stroke mortality and lost DALYs in low- and middle-income countries. The global economic impact of stroke may be dire if effective preventive measures are not implemented to help decrease the burden of this disease. CONCLUSION: The global burden of stroke is high, inclusive of increasing incidence, mortality, DALYs, and economic impact, particularly in low- and middle-income countries. The implementation of better surveillance systems and prevention programs are needed to help track current trends as well as to curb the projected exponential increase in stroke worldwide.
Authors: Carla A Ibrahim-Verbaas; Myriam Fornage; Joshua C Bis; Seung Hoan Choi; Bruce M Psaty; James B Meigs; Madhu Rao; Mike Nalls; Joao D Fontes; Christopher J O'Donnell; Sekar Kathiresan; Georg B Ehret; Caroline S Fox; Rainer Malik; Martin Dichgans; Helena Schmidt; Jari Lahti; Susan R Heckbert; Thomas Lumley; Kenneth Rice; Jerome I Rotter; Kent D Taylor; Aaron R Folsom; Eric Boerwinkle; Wayne D Rosamond; Eyal Shahar; Rebecca F Gottesman; Peter J Koudstaal; Najaf Amin; Renske G Wieberdink; Abbas Dehghan; Albert Hofman; André G Uitterlinden; Anita L Destefano; Stephanie Debette; Luting Xue; Alexa Beiser; Philip A Wolf; Charles Decarli; M Arfan Ikram; Sudha Seshadri; Thomas H Mosley; W T Longstreth; Cornelia M van Duijn; Lenore J Launer Journal: Stroke Date: 2014-01-16 Impact factor: 7.914
Authors: M A Almekhlafi; A Davalos; A Bonafe; R Chapot; J Gralla; V M Pereira; M Goyal Journal: AJNR Am J Neuroradiol Date: 2014-02-20 Impact factor: 3.825
Authors: Joonki Kim; David Yang-Wei Fann; Raymond Chee Seong Seet; Dong-Gyu Jo; Mark P Mattson; Thiruma V Arumugam Journal: Neuromolecular Med Date: 2016-05-18 Impact factor: 3.843