Literature DB >> 22179098

Insight into the role of microRNAs in brain tumors (review).

Alessia Catania1, Francesca Maira, Evangelia Skarmoutsou, Fabio D'Amico, Roger Abounader, Maria Clorinda Mazzarino.   

Abstract

MicroRNAs (MiRNAs) are small non-coding RNAs able to regulate gene expression at a posttranscriptional level. Recent evidence indicates that they play a crucial role in the initiation and progression of human cancers. In this review we briefly describe microRNA biogenesis and function, giving a more detailed account of the current state of knowledge concerning the role of microRNAs in brain tumors and stem-like tumor cells. MicroRNAs control brain tumor development by regulating multiple biological characteristics such as proliferation, invasion, differentiation and angiogenesis. Research in this field is rapidly spreading and encourages potential applications of microRNAs as diagnostic and prognostic tools, in addition to therapeutic targets and tools, to grant clinical benefits to patients suffering of brain tumors.

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Year:  2011        PMID： 22179098     DOI： 10.3892/ijo.2011.1305

Source DB:  PubMed          Journal:  Int J Oncol        ISSN： 1019-6439            Impact factor:   5.650


  9 in total

Review 1.  MicroRNAs in cancer: glioblastoma and glioblastoma cancer stem cells.

Authors:  Jeffrey V Brower; Paul A Clark; Will Lyon; John S Kuo
Journal:  Neurochem Int       Date:  2014-06-14       Impact factor: 3.921

2.  High-throughput microRNA profile in adult and pediatric primary glioblastomas: the role of miR-10b-5p and miR-630 in the tumor aggressiveness.

Authors:  Luiz Guilherme Darrigo Junior; Mirella Baroni; Régia Caroline Peixoto Lira; Silvia Teixeira; Paola Fernanda Fedatto; Vanessa Silva Silveira; Veridiana Kill Suazo; Luciana Chain Veronez; Rodrigo Alexandre Panepucci; David Santos Marco Antônio; José Andres Yunes; Silvia Regina Brandalise; Simone Dos Santos Aguiar; Luciano Neder; Ricardo Santos de Oliveira; Hélio Rubens Machado; Carlos Gilberto Carlotti; Luiz Gonzaga Tone; Elvis Terci Valera; Carlos Alberto Scrideli
Journal:  Mol Biol Rep       Date:  2020-09-04       Impact factor: 2.316

3.  Expression of microRNAs in tumors of the central nervous system in pediatric patients in México.

Authors:  Pilar Eguía-Aguilar; Lisette Gutiérrez-Castillo; Mario Pérezpeña-Díazconti; Jeanette García-Chéquer; Jorge García-Quintana; Fernando Chico-Ponce de León; Luis Gordillo-Domínguez; Samuel Torres-García; Francisco Arenas-Huertero
Journal:  Childs Nerv Syst       Date:  2017-08-16       Impact factor: 1.475

Review 4.  Medulloblastoma epigenetics and the path to clinical innovation.

Authors:  Amanda R Haltom; Stephanie A Toll; Donghang Cheng; Shinji Maegawa; Vidya Gopalakrishnan; Soumen Khatua
Journal:  J Neurooncol       Date:  2020-08-20       Impact factor: 4.130

5.  Dysregulated expression of microRNAs acts as prognostic and diagnostic biomarkers for glioma patients.

Authors:  Yusrah Masood; Manahil Shal; Muhammad Furqan Shah; Maria Fazal Ul Haq; Mahmmood Akhtar Kayani; Ishrat Mahjabeen
Journal:  Mol Genet Genomics       Date:  2022-07-19       Impact factor: 2.980

6.  MicroRNA profile of pediatric pilocytic astrocytomas identifies two tumor-specific signatures when compared to non-neoplastic white matter.

Authors:  Luiz Guilherme Darrigo Júnior; Regia Caroline Peixoto Lira; Paola Fernanda Fedatto; David Santos Marco Antonio; Elvis Terci Valera; Simone Aguiar; José Andres Yunes; Silvia Regina Brandalise; Luciano Neder; Fabiano Pinto Saggioro; Aline Paixão Becker; Ricardo Santos de Oliveira; Hélio Rubens Machado; Rodrigo Alexandre Panepucci; Luiz Gonzaga Tone; Carlos Alberto Scrideli
Journal:  J Neurooncol       Date:  2018-12-20       Impact factor: 4.130

Review 7.  MicroRNA Regulation of Brain Tumour Initiating Cells in Central Nervous System Tumours.

Authors:  Neha Garg; Thusyanth Vijayakumar; David Bakhshinyan; Chitra Venugopal; Sheila K Singh
Journal:  Stem Cells Int       Date:  2015-05-03       Impact factor: 5.443

8.  Anticancer effect of curcumin inhibits cell growth through miR-21/PTEN/Akt pathway in breast cancer cell.

Authors:  Xinzheng Wang; Yakai Hang; Jinbiao Liu; Yongqiang Hou; Ning Wang; Mingjun Wang
Journal:  Oncol Lett       Date:  2017-04-20       Impact factor: 2.967

9.  Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim.

Authors:  Desiree Hunt Floyd; Ying Zhang; Bijan K Dey; Benjamin Kefas; Hannah Breit; Kaitlyn Marks; Anindya Dutta; Christel Herold-Mende; Michael Synowitz; Rainer Glass; Roger Abounader; Benjamin W Purow
Journal:  PLoS One       Date:  2014-05-07       Impact factor: 3.240
  9 in total

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