Literature DB >> 22178015

Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective.

Paul McVeigh1, Aaron G Maule, John P Dalton, Mark W Robinson.   

Abstract

Fasciola hepatica is a food-borne parasite of animals and humans. It secretes a large family of cysteine peptidases, termed cathepsins, that are important virulence factors. Here, we discuss how advances in molecular technologies have helped to probe the function of liver fluke cathepsins, and consider how evolving systems/molecular biology approaches can continue to inform our understanding of these important parasite enzymes. Copyright Â
© 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

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Year:  2011        PMID: 22178015     DOI: 10.1016/j.micinf.2011.11.012

Source DB:  PubMed          Journal:  Microbes Infect        ISSN: 1286-4579            Impact factor:   2.700


  15 in total

1.  Extracellular vesicle-mediated communication in host-parasite interactions: insight from Fasciola hepatica.

Authors:  Eduardo de la Torre-Escudero; Mark W Robinson
Journal:  Ann Transl Med       Date:  2017-05

2.  Secreted cathepsin L-like peptidases are involved in the degradation of trapped antibodies on the surface of Echinostoma caproni.

Authors:  Alba Cortés; Libor Mikeš; Carla Muñoz-Antolí; María Álvarez-Izquierdo; J Guillermo Esteban; Petr Horák; Rafael Toledo
Journal:  Parasitol Res       Date:  2019-11-12       Impact factor: 2.289

3.  The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution.

Authors:  Krystyna Cwiklinski; John Pius Dalton; Philippe J Dufresne; James La Course; Diana Jl Williams; Jane Hodgkinson; Steve Paterson
Journal:  Genome Biol       Date:  2015-04-03       Impact factor: 13.583

4.  Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches.

Authors:  Lilian Hernández Alvarez; Dany Naranjo Feliciano; Jorge Enrique Hernández González; R O Soares; Rosemberg de Oliveira Soares; Diego Enry Barreto Gomes; Pedro Geraldo Pascutti
Journal:  PLoS Negl Trop Dis       Date:  2015-05-15

5.  Genome analysis of Excretory/Secretory proteins in Taenia solium reveals their Abundance of Antigenic Regions (AAR).

Authors:  Sandra Gomez; Laura Adalid-Peralta; Hector Palafox-Fonseca; Vito Adrian Cantu-Robles; Xavier Soberón; Edda Sciutto; Gladis Fragoso; Raúl J Bobes; Juan P Laclette; Luis del Pozo Yauner; Adrián Ochoa-Leyva
Journal:  Sci Rep       Date:  2015-05-19       Impact factor: 4.379

6.  Transcriptional analysis identifies key genes involved in metabolism, fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver.

Authors:  Cristian A Alvarez Rojas; Brendan R E Ansell; Ross S Hall; Robin B Gasser; Neil D Young; Aaron R Jex; Jean-Pierre Y Scheerlinck
Journal:  Parasit Vectors       Date:  2015-02-25       Impact factor: 3.876

7.  RNAi dynamics in Juvenile Fasciola spp. Liver flukes reveals the persistence of gene silencing in vitro.

Authors:  Paul McVeigh; Erin M McCammick; Paul McCusker; Russell M Morphew; Angela Mousley; Abbas Abidi; Khalid M Saifullah; Raman Muthusamy; Ravikumar Gopalakrishnan; Terry W Spithill; John P Dalton; Peter M Brophy; Nikki J Marks; Aaron G Maule
Journal:  PLoS Negl Trop Dis       Date:  2014-09-25

8.  Cysteine peptidases of Eudiplozoon nipponicum: a broad repertoire of structurally assorted cathepsins L in contrast to the scarcity of cathepsins B in an invasive species of haematophagous monogenean of common carp.

Authors:  Lucie Jedličková; Hana Dvořáková; Jan Dvořák; Martin Kašný; Lenka Ulrychová; Jiří Vorel; Vojtěch Žárský; Libor Mikeš
Journal:  Parasit Vectors       Date:  2018-03-06       Impact factor: 3.876

9.  Helminth secretome database (HSD): a collection of helminth excretory/secretory proteins predicted from expressed sequence tags (ESTs).

Authors:  Gagan Garg; Shoba Ranganathan
Journal:  BMC Genomics       Date:  2012-12-13       Impact factor: 3.969

10.  Definitive host influences the proteomic profile of excretory/secretory products of the trematode Echinostoma caproni.

Authors:  Alba Cortés; Javier Sotillo; Carla Muñoz-Antolí; María Trelis; J Guillermo Esteban; Rafael Toledo
Journal:  Parasit Vectors       Date:  2016-03-31       Impact factor: 3.876

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