Literature DB >> 22173886

A traceless vascular-targeting antibody-drug conjugate for cancer therapy.

Gonçalo J L Bernardes1, Giulio Casi, Sabrina Trüssel, Isabelle Hartmann, Kathrin Schwager, Jörg Scheuermann, Dario Neri.   

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Year:  2011        PMID： 22173886     DOI： 10.1002/anie.201106527

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  25 in total

1.  Site-specific chemical modification of antibody fragments using traceless cleavable linkers.

Authors:  Gonçalo J L Bernardes; Martina Steiner; Isabelle Hartmann; Dario Neri; Giulio Casi
Journal:  Nat Protoc       Date:  2013-10-03       Impact factor: 13.491

2.  An atlas of bloodstream-accessible bone marrow proteins for site-directed therapy of acute myeloid leukemia.

Authors:  L Angenendt; S Reuter; D Kentrup; A S Benk; F Neumann; J Hüve; A C Martens; C Schwöppe; T Kessler; L H Schmidt; T Sauer; C Brand; J-H Mikesch; G Lenz; R M Mesters; C Müller-Tidow; W Hartmann; E Wardelmann; D Neri; W E Berdel; C Roesli; C Schliemann
Journal:  Leukemia       Date:  2017-06-30       Impact factor: 11.528

3.  The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma.

Authors:  Peter D Senter; Eric L Sievers
Journal:  Nat Biotechnol       Date:  2012-07-10       Impact factor: 54.908

Review 4.  Field Guide to Challenges and Opportunities in Antibody-Drug Conjugates for Chemists.

Authors:  Mallory R Gordon; Mine Canakci; Longyu Li; Jiaming Zhuang; Barbara Osborne; S Thayumanavan
Journal:  Bioconjug Chem       Date:  2015-09-10       Impact factor: 4.774

5.  Protease-Cleavable Linkers Modulate the Anticancer Activity of Noninternalizing Antibody-Drug Conjugates.

Authors:  Alberto Dal Corso; Samuele Cazzamalli; Rémy Gébleux; Martin Mattarella; Dario Neri
Journal:  Bioconjug Chem       Date:  2017-07-06       Impact factor: 4.774

6.  Chemically Defined Antibody- and Small Molecule-Drug Conjugates for in Vivo Tumor Targeting Applications: A Comparative Analysis.

Authors:  Samuele Cazzamalli; Alberto Dal Corso; Fontaine Widmayer; Dario Neri
Journal:  J Am Chem Soc       Date:  2018-01-27       Impact factor: 15.419

7.  Enhanced Therapeutic Activity of Non-Internalizing Small-Molecule-Drug Conjugates Targeting Carbonic Anhydrase IX in Combination with Targeted Interleukin-2.

Authors:  Samuele Cazzamalli; Barbara Ziffels; Fontaine Widmayer; Patrizia Murer; Giovanni Pellegrini; Francesca Pretto; Sarah Wulhfard; Dario Neri
Journal:  Clin Cancer Res       Date:  2018-04-24       Impact factor: 12.531

8.  Non-internalizing antibody-drug conjugates display potent anti-cancer activity upon proteolytic release of monomethyl auristatin E in the subendothelial extracellular matrix.

Authors:  Rémy Gébleux; Marco Stringhini; Ruben Casanova; Alex Soltermann; Dario Neri
Journal:  Int J Cancer       Date:  2016-12-30       Impact factor: 7.396

9.  Antibody Format and Drug Release Rate Determine the Therapeutic Activity of Noninternalizing Antibody-Drug Conjugates.

Authors:  Rémy Gébleux; Sarah Wulhfard; Giulio Casi; Dario Neri
Journal:  Mol Cancer Ther       Date:  2015-08-20       Impact factor: 6.261

10.  Acetazolamide Serves as Selective Delivery Vehicle for Dipeptide-Linked Drugs to Renal Cell Carcinoma.

Authors:  Samuele Cazzamalli; Alberto Dal Corso; Dario Neri
Journal:  Mol Cancer Ther       Date:  2016-09-08       Impact factor: 6.261
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