Literature DB >> 29342352

Chemically Defined Antibody- and Small Molecule-Drug Conjugates for in Vivo Tumor Targeting Applications: A Comparative Analysis.

Samuele Cazzamalli1, Alberto Dal Corso1, Fontaine Widmayer1, Dario Neri1.   

Abstract

We present the first direct comparative evaluation of an antibody-drug conjugate and of a small molecule-drug conjugate for cancer therapy, using chemically defined products which bind with high-affinity to carbonic anhydrase IX, a marker of tumor hypoxia and of renal cell carcinoma.

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Year:  2018        PMID： 29342352      PMCID： PMC5844464          DOI： 10.1021/jacs.7b13361

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  49 in total

1.  Therapeutic mechanism and efficacy of the antibody-drug conjugate BAY 79-4620 targeting human carbonic anhydrase 9.

Authors:  Heike M Petrul; Christoph A Schatz; Charlotte C Kopitz; Lila Adnane; Timothy J McCabe; Pamela Trail; Sha Ha; Yong S Chang; Andrei Voznesensky; Gerald Ranges; Paul P Tamburini
Journal:  Mol Cancer Ther       Date:  2011-12-06       Impact factor: 6.261

2.  Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment.

Authors:  Charlotte F McDonagh; Eileen Turcott; Lori Westendorf; Jennifer B Webster; Stephen C Alley; Kristine Kim; Jamie Andreyka; Ivan Stone; Kevin J Hamblett; Joseph A Francisco; Paul Carter
Journal:  Protein Eng Des Sel       Date:  2006-04-27       Impact factor: 1.650

3.  Evaluation of Nonpeptidic Ligand Conjugates for the Treatment of Hypoxic and Carbonic Anhydrase IX-Expressing Cancers.

Authors:  Peng-Cheng Lv; Jyoti Roy; Karson S Putt; Philip S Low
Journal:  Mol Cancer Ther       Date:  2016-12-15       Impact factor: 6.261

Review 4.  Antibody-drug conjugates: an emerging concept in cancer therapy.

Authors:  Ravi V J Chari; Michael L Miller; Wayne C Widdison
Journal:  Angew Chem Int Ed Engl       Date:  2014-02-20       Impact factor: 15.336

Review 5.  Carbonic anhydrases: current state of the art, therapeutic applications and future prospects.

Authors:  Silvia Pastorekova; Seppo Parkkila; Jaromir Pastorek; Claudiu T Supuran
Journal:  J Enzyme Inhib Med Chem       Date:  2004-06       Impact factor: 5.051

6.  Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group.

Authors:  Eric Van Cutsem; Vladimir M Moiseyenko; Sergei Tjulandin; Alejandro Majlis; Manuel Constenla; Corrado Boni; Adriano Rodrigues; Miguel Fodor; Yee Chao; Edouard Voznyi; Marie-Laure Risse; Jaffer A Ajani
Journal:  J Clin Oncol       Date:  2006-11-01       Impact factor: 44.544

Review 7.  Developments in the use of antibody-drug conjugates.

Authors:  Howard A Burris
Journal:  Am Soc Clin Oncol Educ Book       Date:  2013

8.  Evaluation of Nonpeptidic Ligand Conjugates for SPECT Imaging of Hypoxic and Carbonic Anhydrase IX-Expressing Cancers.

Authors:  Peng-Cheng Lv; Karson S Putt; Philip S Low
Journal:  Bioconjug Chem       Date:  2016-07-07       Impact factor: 4.774

9.  Five-year results of brentuximab vedotin in patients with relapsed or refractory systemic anaplastic large cell lymphoma.

Authors:  Barbara Pro; Ranjana Advani; Pauline Brice; Nancy L Bartlett; Joseph D Rosenblatt; Tim Illidge; Jeffrey Matous; Radhakrishnan Ramchandren; Michelle Fanale; Joseph M Connors; Keenan Fenton; Dirk Huebner; Juan M Pinelli; Dana A Kennedy; Andrei Shustov
Journal:  Blood       Date:  2017-10-03       Impact factor: 22.113

Review 10.  Potent antibody drug conjugates for cancer therapy.

Authors:  Peter D Senter
Journal:  Curr Opin Chem Biol       Date:  2009-05-04       Impact factor: 8.822
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  30 in total

1.  Antibody Conjugate Assembly on Ultrasound-Confined Microcarrier Particles.

Authors:  Michael M Binkley; Mingyang Cui; Mikhail Y Berezin; J Mark Meacham
Journal:  ACS Biomater Sci Eng       Date:  2020-10-09

2.  Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications.

Authors:  Nicholas Favalli; Gabriele Bassi; Christian Pellegrino; Jacopo Millul; Roberto De Luca; Samuele Cazzamalli; Su Yang; Anika Trenner; Nour L Mozaffari; Renier Myburgh; Mustafa Moroglu; Stuart J Conway; Alessandro A Sartori; Markus G Manz; Richard A Lerner; Peter K Vogt; Jörg Scheuermann; Dario Neri
Journal:  Nat Chem       Date:  2021-04-08       Impact factor: 24.427

3.  Antibody-Based Delivery of Cytokine Payloads to Carbonic Anhydrase IX Leads to Cancer Cures in Immunocompetent Tumor-Bearing Mice.

Authors:  Barbara Ziffels; Marco Stringhini; Philipp Probst; Tim Fugmann; Theo Sturm; Dario Neri
Journal:  Mol Cancer Ther       Date:  2019-06-18       Impact factor: 6.261

Review 4.  DNA-Encoded Chemical Libraries: A Comprehensive Review with Succesful Stories and Future Challenges.

Authors:  Adrián Gironda-Martínez; Etienne J Donckele; Florent Samain; Dario Neri
Journal:  ACS Pharmacol Transl Sci       Date:  2021-06-14

Review 5.  New Technologies Bloom Together for Bettering Cancer Drug Conjugates.

Authors:  Yiming Jin; Shahab Edalatian Zakeri; Raman Bahal; Andrew J Wiemer
Journal:  Pharmacol Rev       Date:  2022-07       Impact factor: 18.923

Review 6.  Targeting carbonic anhydrase IX and XII isoforms with small molecule inhibitors and monoclonal antibodies.

Authors:  Mateusz Kciuk; Adrianna Gielecińska; Somdutt Mujwar; Mariusz Mojzych; Beata Marciniak; Rafał Drozda; Renata Kontek
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.756

7.  Cellular-Resolution Imaging of Bystander Payload Tissue Penetration from Antibody-Drug Conjugates.

Authors:  Eshita Khera; Shujun Dong; Haolong Huang; Laureen de Bever; Floris L van Delft; Greg M Thurber
Journal:  Mol Cancer Ther       Date:  2021-12-15       Impact factor: 6.009

Review 8.  Therapeutic potential of targeting the Eph/ephrin signaling complex.

Authors:  Nayanendu Saha; Dorothea Robev; Emilia O Mason; Juha P Himanen; Dimitar B Nikolov
Journal:  Int J Biochem Cell Biol       Date:  2018-10-19       Impact factor: 5.085

9.  An ultra-high-affinity small organic ligand of fibroblast activation protein for tumor-targeting applications.

Authors:  Jacopo Millul; Gabriele Bassi; Jacqueline Mock; Abdullah Elsayed; Christian Pellegrino; Aureliano Zana; Sheila Dakhel Plaza; Lisa Nadal; Andreas Gloger; Eleonore Schmidt; Ilaria Biancofiore; Etienne J Donckele; Florent Samain; Dario Neri; Samuele Cazzamalli
Journal:  Proc Natl Acad Sci U S A       Date:  2021-04-20       Impact factor: 11.205

10.  Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1.

Authors:  Marco Catalano; Gabriele Bassi; Giulia Rotondi; Lyna Khettabi; Maria Dichiara; Patrizia Murer; Jörg Scheuermann; Montserrat Soler-Lopez; Dario Neri
Journal:  RSC Med Chem       Date:  2020-11-13
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