Literature DB >> 22172916

A low cost color visual stimulator for fMRI.

Bill Rogers1, Yen-Yu I Shih, Bryan De La Garza, Joseph M Harrison, John Roby, Timothy Q Duong.   

Abstract

This low cost visual stimulator was developed for use in small animal imaging. The stimulator uses a single tri-color LED for each eye and can output red, green, or blue light or any combination of the three. When all three LED colors are illuminated at the same time achromatic light is the output. The stimulator is almost entirely implemented in software with only minimal electronics. The LEDs are controlled via the parallel port of a desktop computer. Flicker frequency, wavelength, intensity and waveform shape are under software control. The LEDs are coupled to fiber optic cables which run into the MRI scanner room leaving the LEDs and the power source in the control room. Calibration with a radiometer shows the light output to be very linear from zero to full intensity. The stimulator was used in fMRI visual stimulation studies performed on Sprague Dawley rats with an 11.7Tesla magnet. As the stimulator is software driven, modifications to accommodate other protocols and extensions for new functionality can be readily incorporated. With this in mind, the visual stimulator circuit diagram and software including source code are available upon request.
Copyright © 2011 Elsevier B.V. All rights reserved.

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Year:  2011        PMID: 22172916      PMCID: PMC3273662          DOI: 10.1016/j.jneumeth.2011.10.032

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  14 in total

1.  High-resolution mapping of iso-orientation columns by fMRI.

Authors:  D S Kim; T Q Duong; S G Kim
Journal:  Nat Neurosci       Date:  2000-02       Impact factor: 24.884

2.  Critical flicker frequency responses in visual cortex.

Authors:  E F Wells; G M Bernstein; B W Scott; P J Bennett; J R Mendelson
Journal:  Exp Brain Res       Date:  2001-07       Impact factor: 1.972

3.  Behavioral measurements of rat spectral sensitivity.

Authors:  D Birch; G H Jacobs
Journal:  Vision Res       Date:  1975-06       Impact factor: 1.886

4.  Diffuse luminance flicker increases blood flow in major retinal arteries and veins.

Authors:  G Garhöfer; C Zawinka; H Resch; K H Huemer; G T Dorner; L Schmetterer
Journal:  Vision Res       Date:  2004-04       Impact factor: 1.886

5.  Mapping cone- and rod-induced retinal responsiveness in macaque retina by optical imaging.

Authors:  Kazushige Tsunoda; Yoshihisa Oguchi; Gen Hanazono; Manabu Tanifuji
Journal:  Invest Ophthalmol Vis Sci       Date:  2004-10       Impact factor: 4.799

6.  Light stimulus frequency dependence of activity in the rat visual system as studied with high-resolution BOLD fMRI.

Authors:  Nadja Van Camp; Marleen Verhoye; Chris I De Zeeuw; Annemie Van der Linden
Journal:  J Neurophysiol       Date:  2006-01-04       Impact factor: 2.714

Review 7.  Visually evoked hemodynamical response and assessment of neurovascular coupling in the optic nerve and retina.

Authors:  Charles E Riva; Eric Logean; Benedetto Falsini
Journal:  Prog Retin Eye Res       Date:  2004-10-22       Impact factor: 21.198

8.  Lamina-specific functional MRI of retinal and choroidal responses to visual stimuli.

Authors:  Yen-Yu I Shih; Bryan H De la Garza; Eric R Muir; William E Rogers; Joseph M Harrison; Jeffrey W Kiel; Timothy Q Duong
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-07-15       Impact factor: 4.799

9.  Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration.

Authors:  Anding Bi; Jinjuan Cui; Yu-Ping Ma; Elena Olshevskaya; Mingliang Pu; Alexander M Dizhoor; Zhuo-Hua Pan
Journal:  Neuron       Date:  2006-04-06       Impact factor: 17.173

10.  Reexamination of spectral mechanisms in the rat (Rattus norvegicus).

Authors:  J Neitz; G H Jacobs
Journal:  J Comp Psychol       Date:  1986-03       Impact factor: 2.231

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  1 in total

1.  Quantitative retinal and choroidal blood flow during light, dark adaptation and flicker light stimulation in rats using fluorescent microspheres.

Authors:  Yen-Yu I Shih; Lin Wang; Bryan H De La Garza; Guang Li; Grant Cull; Jeffery W Kiel; Timothy Q Duong
Journal:  Curr Eye Res       Date:  2013-01-14       Impact factor: 2.424

  1 in total

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