Literature DB >> 22172665

Tracking intron removal in real time.

Bruce A Hamilton1, Xiang-Dong Fu.   

Abstract

Are all introns spliced cotranscriptionally? In a recent issue of Cell, Vargas et al. (2011) reported single-molecule analyses of pre-mRNA splicing, confirming transcription-coupled splicing of constitutive introns but finding off-site and delayed splicing of alternative introns. The results raise the question of whether kinetics distinguishes constitutive from regulated splicing.
Copyright © 2011 Elsevier Inc. All rights reserved.

Entities:  

Year:  2011        PMID: 22172665      PMCID: PMC4442631          DOI: 10.1016/j.devcel.2011.11.010

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  10 in total

Review 1.  Pre-mRNA splicing: where and when in the nucleus.

Authors:  Joonhee Han; Ji Xiong; Dong Wang; Xiang-Dong Fu
Journal:  Trends Cell Biol       Date:  2011-04-21       Impact factor: 20.808

Review 2.  Nuclear speckles: a model for nuclear organelles.

Authors:  Angus I Lamond; David L Spector
Journal:  Nat Rev Mol Cell Biol       Date:  2003-08       Impact factor: 94.444

Review 3.  Functional integration of transcriptional and RNA processing machineries.

Authors:  Shatakshi Pandit; Dong Wang; Xiang-Dong Fu
Journal:  Curr Opin Cell Biol       Date:  2008-04-22       Impact factor: 8.382

Review 4.  Pause locally, splice globally.

Authors:  Fernando Carrillo Oesterreich; Nicole Bieberstein; Karla M Neugebauer
Journal:  Trends Cell Biol       Date:  2011-04-27       Impact factor: 20.808

5.  Single-molecule imaging of transcriptionally coupled and uncoupled splicing.

Authors:  Diana Y Vargas; Khyati Shah; Mona Batish; Michael Levandoski; Sourav Sinha; Salvatore A E Marras; Paul Schedl; Sanjay Tyagi
Journal:  Cell       Date:  2011-11-23       Impact factor: 41.582

6.  A role for TREX components in the release of spliced mRNA from nuclear speckle domains.

Authors:  Anusha P Dias; Kobina Dufu; Haixin Lei; Robin Reed
Journal:  Nat Commun       Date:  2010-10-19       Impact factor: 14.919

7.  Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila.

Authors:  L R Bell; J I Horabin; P Schedl; T W Cline
Journal:  Cell       Date:  1991-04-19       Impact factor: 41.582

Review 8.  Epigenetics in alternative pre-mRNA splicing.

Authors:  Reini F Luco; Mariano Allo; Ignacio E Schor; Alberto R Kornblihtt; Tom Misteli
Journal:  Cell       Date:  2011-01-07       Impact factor: 41.582

9.  Splicing-dependent RNA polymerase pausing in yeast.

Authors:  Ross D Alexander; Steven A Innocente; J David Barrass; Jean D Beggs
Journal:  Mol Cell       Date:  2010-11-24       Impact factor: 19.328

10.  A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.

Authors:  Paul L Boutz; Peter Stoilov; Qin Li; Chia-Ho Lin; Geetanjali Chawla; Kristin Ostrow; Lily Shiue; Manuel Ares; Douglas L Black
Journal:  Genes Dev       Date:  2007-07-01       Impact factor: 11.361

  10 in total
  2 in total

1.  Splicing of mouse p53 pre-mRNA does not always follow the "first come, first served" principle and may be influenced by cisplatin treatment and serum starvation.

Authors:  Min Yang; Jack Wu; Si-Hung Wu; An-Ding Bi; D Joshua Liao
Journal:  Mol Biol Rep       Date:  2012-06-28       Impact factor: 2.316

2.  The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export.

Authors:  Eleonora Zonta; Danielle Bittencourt; Samaan Samaan; Sophie Germann; Martin Dutertre; Didier Auboeuf
Journal:  Nucleic Acids Res       Date:  2012-11-11       Impact factor: 16.971

  2 in total

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