Literature DB >> 22165663

Incidence and risk factors for lumbar degenerative disc disease in the United States military 1999-2008.

Andrew J Schoenfeld1, James H Nelson, Robert Burks, Philip J Belmont.   

Abstract

The epidemiology of lumbar degenerative disc disease (DDD) is poorly understood, and the incidence of this disorder has not previously been characterized for a young, physically active population. This study sought to evaluate the incidence of lumbar DDD, and identify risk factors for its development, among individuals serving in the U.S. military over a 10-year period. The Defense Medical Epidemiology Database was queried for the years 1999-2008 using the International Classification of Diseases, Ninth Revision, Clinical Modification code for lumbar disc degeneration (722.52). Overall incidence was determined and multivariate Poisson regression analysis was performed to identify risk factors among demographic characteristics such as age, sex, race, military rank, and branch of service. White race, female sex, Army, Air Force, or Marine service, enlisted positions within the ranks, and age were found to be significant risk factors for the development of lumbar disc degeneration. Increased age appeared to be one of the most important risk factors, with adjusted incidence rates successively increasing for each age group under study. The incidence of lumbar DDD in this young, racially diverse, and physically active population is higher than most other degenerative conditions.

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Year:  2011        PMID: 22165663     DOI: 10.7205/milmed-d-11-00061

Source DB:  PubMed          Journal:  Mil Med        ISSN: 0026-4075            Impact factor:   1.437


  10 in total

Review 1.  Cell and molecular biology of intervertebral disc degeneration: current understanding and implications for potential therapeutic strategies.

Authors:  S Z Wang; Y F Rui; J Lu; C Wang
Journal:  Cell Prolif       Date:  2014-08-11       Impact factor: 6.831

Review 2.  Does Patient Sex Affect the Rate of Mortality and Complications After Spine Surgery? A Systematic Review.

Authors:  Andrew J Schoenfeld; Elyse N Reamer; Emily I Wynkoop; Hwajung Choi; Christopher M Bono
Journal:  Clin Orthop Relat Res       Date:  2015-08       Impact factor: 4.176

3.  Anemia was associated with multilevel lumbar disc degeneration in patients with low back pain: a single-center retrospective study.

Authors:  Hengrui Chang; Xianda Gao; Xiangyu Li; Ruoyu Zhao; Wenyuan Ding
Journal:  Eur Spine J       Date:  2022-05-21       Impact factor: 2.721

4.  Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.

Authors:  Christian Isaac; Adam Wright; Arvydas Usas; Hongshuai Li; Ying Tang; Xiaodong Mu; Nicholas Greco; Qing Dong; Nam Vo; James Kang; Bing Wang; Johnny Huard
Journal:  J Orthop Res       Date:  2012-10-23       Impact factor: 3.494

5.  Does Degenerative Lumbar Spine Disease Influence Femoroacetabular Flexion in Patients Undergoing Total Hip Arthroplasty?

Authors:  Christina I Esposito; Theodore T Miller; Han Jo Kim; Brian T Barlow; Timothy M Wright; Douglas E Padgett; Seth A Jerabek; David J Mayman
Journal:  Clin Orthop Relat Res       Date:  2016-03-28       Impact factor: 4.176

6.  Chiropractic management of a veteran with lower back pain associated with diffuse idiopathic skeletal hypertrophy and degenerative disk disease.

Authors:  Jan A Roberts; Tristy M Wolfe
Journal:  J Chiropr Med       Date:  2012-12

7.  Polymorphism in the hypoxia-inducible factor 1alpha gene may confer susceptibility to LDD in Chinese cohort.

Authors:  Wen-Ping Lin; Xue-Jin Wang; Cong-Ren Wang; Li-Qun Zhang; Neng Li; Fa-Sheng Wang; Jian-Hua Lin
Journal:  PLoS One       Date:  2013-08-26       Impact factor: 3.240

8.  Apparent Diffusion Coefficient of Diffusion-Weighted Imaging in Evaluation of Cervical Intervertebral Disc Degeneration: An Observational Study with 3.0 T Magnetic Resonance Imaging.

Authors:  Pinjie Chen; Chunlei Wu; Minghua Huang; Guangjian Jin; Qinglei Shi; Zhihua Han; Chun Chen
Journal:  Biomed Res Int       Date:  2018-02-18       Impact factor: 3.411

9.  Effects of controlled hypotension with restrictive transfusion on intraoperative blood loss and systemic oxygen metabolism in elderly patients who underwent lumbar fusion.

Authors:  Xiaodong Qiu; Zhiying Tan; Wenhao Tang; Hui Ye; Xinjian Lu
Journal:  Trials       Date:  2021-01-28       Impact factor: 2.279

Review 10.  Enhancing intervertebral disc repair and regeneration through biology: platelet-rich plasma as an alternative strategy.

Authors:  Shan-Zheng Wang; Yun-Feng Rui; Qi Tan; Chen Wang
Journal:  Arthritis Res Ther       Date:  2013       Impact factor: 5.156

  10 in total

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