Literature DB >> 22162563

Strong correlation between liver and serum levels of hepatitis C virus core antigen and RNA in chronically infected patients.

V Descamps1, A Op de Beeck, C Plassart, E Brochot, C François, F Helle, M Adler, N Bourgeois, D Degré, G Duverlie, S Castelain.   

Abstract

HCV core antigen (Ag) and HCV RNA levels were evaluated in matched liver biopsy samples and sera from 22 patients with hepatitis C infection by using the quantitative Architect HCV Ag immunoassay and a real-time RT-qPCR assay, respectively. The data showed a strong correlation between liver and serum compartments of HCV Ag levels (r = 0.80) and HCV RNA levels (r = 0.87). In summary, the serum HCV Ag and RNA levels reflect the intrahepatic values.

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Year:  2011        PMID： 22162563      PMCID： PMC3264181          DOI： 10.1128/JCM.06503-11

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  22 in total

1.  Quantification of hepatitis C virus in human liver and serum samples by using LightCycler reverse transcriptase PCR.

Authors:  Peter A White; Yong Pan; Anthony J Freeman; George Marinos; Rosemary A Ffrench; Andrew R Lloyd; William D Rawlinson
Journal:  J Clin Microbiol       Date:  2002-11       Impact factor: 5.948

2.  Intrahepatic hepatitis C virus replication is increased in patients with regular alcohol consumption.

Authors:  M Romero-Gómez; L Grande; M C Nogales; M Fernández; M Chavez; M Castro
Journal:  Dig Liver Dis       Date:  2001-11       Impact factor: 4.088

3.  Benefit of hepatitis C virus core antigen assay in prediction of therapeutic response to interferon and ribavirin combination therapy.

Authors:  Masahiko Takahashi; Hidetsugu Saito; Makiko Higashimoto; Kazuhiro Atsukawa; Hiromasa Ishii
Journal:  J Clin Microbiol       Date:  2005-01       Impact factor: 5.948

4.  Standardization of hepatitis C virus RNA quantification.

Authors:  J M Pawlotsky; M Bouvier-Alias; C Hezode; F Darthuy; J Remire; D Dhumeaux
Journal:  Hepatology       Date:  2000-09       Impact factor: 17.425

5.  Quantitative determination of hepatitis C core antigen in therapy monitoring for chronic hepatitis C.

Authors:  Giovanna A Moscato; Gianluigi Giannelli; Barbara Grandi; Daniela Pieri; Ombretta Marsi; Isabella Guarducci; Irene Batini; Emanuele Altomare; Salvatore Antonaci; Alfonso Capria; Giovanni Pellegrini; Rodolfo Sacco
Journal:  Intervirology       Date:  2010-09-10       Impact factor: 1.763

6.  Quantification of hepatitis C virus (HCV) in liver specimens and sera from patients with human immunodeficiency virus coinfection by using the Versant HCV RNA 3.0 (branched DNA-based) DNA assay.

Authors:  Rosamaria Tedeschi; Eliana Pivetta; Stefania Zanussi; Ettore Bidoli; Mirna Ros; Giampiero di Gennaro; Guglielmo Nasti; Paolo De Paoli
Journal:  J Clin Microbiol       Date:  2003-07       Impact factor: 5.948

7.  Variable ratio of hepatitis C virus RNA to viral core antigen in patient sera.

Authors:  Christian G Schüttler; Christine Thomas; Thomas Discher; Georg Friese; Jürgen Lohmeyer; Ralph Schuster; Stephan Schaefer; Wolfram H Gerlich
Journal:  J Clin Microbiol       Date:  2004-05       Impact factor: 5.948

8.  TaqMan amplification system with an internal positive control for HCV RNA quantitation.

Authors:  Sandrine Castelain; Véronique Descamps; Vincent Thibault; Catherine François; Dorine Bonte; Virginie Morel; Jacques Izopet; Dominique Capron; Patricia Zawadzki; Gilles Duverlie
Journal:  J Clin Virol       Date:  2004-11       Impact factor: 3.168

9.  Clinical utility of total HCV core antigen quantification: a new indirect marker of HCV replication.

Authors:  Magali Bouvier-Alias; Keyur Patel; Harel Dahari; Stéphanie Beaucourt; Patrick Larderie; Lawrence Blatt; Christophe Hezode; Gaston Picchio; Daniel Dhumeaux; Avidan U Neumann; John G McHutchison; Jean-Michel Pawlotsky
Journal:  Hepatology       Date:  2002-07       Impact factor: 17.425

10.  Intrahepatic hepatitis C virus RNA quantification in microdissected hepatocytes.

Authors:  Giovanna Vona; Rosella Tuveri; Oona Delpuech; Anais Vallet; Danielle Canioni; Giorgio Ballardini; Jean Baptiste Trabut; Brigitte Le Bail; Bertrand Nalpas; Françoise Carnot; Stanislas Pol; Christian Brechot; Valérie Thiers
Journal:  J Hepatol       Date:  2004-04       Impact factor: 25.083
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  18 in total

Review 1.  New virologic tools for management of chronic hepatitis B and C.

Authors:  Stéphane Chevaliez; Christophe Rodriguez; Jean-Michel Pawlotsky
Journal:  Gastroenterology       Date:  2012-05       Impact factor: 22.682

2.  Probable hepatitis C virus transmission from a seronegative blood donor via cellular blood products.

Authors:  Servet U Biceroglu; Ajda Turhan; Aysu D Doskaya; Tansu Yamazhan; Ayhan Donmez; Imre Altuglu; Yesim Aydinok; Ruchan Y Sertoz
Journal:  Blood Transfus       Date:  2013-05-06       Impact factor: 3.443

3.  Quantification of C4d deposition and hepatitis C virus RNA in tissue in cases of graft rejection and hepatitis C recurrence after liver transplantation.

Authors:  Alice Tung Wan Song; Evandro Sobroza de Mello; Venâncio Avancini Ferreira Alves; Norma de Paula Cavalheiro; Carlos Eduardo Melo; Patricia Rodrigues Bonazzi; Fatima Mitiko Tengan; Maristela Pinheiro Freire; Antonio Alci Barone; Luiz Augusto Carneiro D'Albuquerque; Edson Abdala
Journal:  Mem Inst Oswaldo Cruz       Date:  2015-02-13       Impact factor: 2.743

Review 4.  Hepatitis C virus in the new era: perspectives in epidemiology, prevention, diagnostics and predictors of response to therapy.

Authors:  Filippo Ansaldi; Andrea Orsi; Laura Sticchi; Bianca Bruzzone; Giancarlo Icardi
Journal:  World J Gastroenterol       Date:  2014-08-07       Impact factor: 5.742

5.  A rapid, low-cost quantitative diagnostic method for hepatitis C virus infection using capillary zone electrophoresis.

Authors:  A M Attallah; S O Abdallah; M A El-Desouky; M El-Far; M M Omran; K Farid; M A Abdelrazek; M N Shabaka; H Zaghloul; A M Fawzy; F B Bazeed
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-11-20       Impact factor: 3.267

Review 6.  Tools for the diagnosis of hepatitis C virus infection and hepatic fibrosis staging.

Authors:  Verónica Saludes; Victoria González; Ramon Planas; Lurdes Matas; Vicente Ausina; Elisa Martró
Journal:  World J Gastroenterol       Date:  2014-04-07       Impact factor: 5.742

Review 7.  Hepatitis C Core Antigen Testing for Diagnosis of Hepatitis C Virus Infection: A Systematic Review and Meta-analysis.

Authors:  J Morgan Freiman; Trang M Tran; Samuel G Schumacher; Laura F White; Stefano Ongarello; Jennifer Cohn; Philippa J Easterbrook; Benjamin P Linas; Claudia M Denkinger
Journal:  Ann Intern Med       Date:  2016-06-21       Impact factor: 25.391

8.  Usefulness of a fourth generation ELISA assay for the reliable identification of HCV infection in HIV-positive adults from Gabon (Central Africa).

Authors:  François Rouet; Luc Deleplancque; Berthold Bivigou Mboumba; Jeanne Sica; Augustin Mouinga-Ondémé; Florian Liégeois; Alain Goudeau; Frédéric Dubois; Catherine Gaudy-Graffin
Journal:  PLoS One       Date:  2015-01-24       Impact factor: 3.240

9.  Increased microRNA-155 expression in the serum and peripheral monocytes in chronic HCV infection.

Authors:  Shashi Bala; Yaphet Tilahun; Odette Taha; Hawau Alao; Karen Kodys; Donna Catalano; Gyongyi Szabo
Journal:  J Transl Med       Date:  2012-07-30       Impact factor: 5.531

10.  Permissivity of primary human hepatocytes and different hepatoma cell lines to cell culture adapted hepatitis C virus.

Authors:  Francois Helle; Etienne Brochot; Carole Fournier; Véronique Descamps; Laure Izquierdo; Thomas W Hoffmann; Virginie Morel; Yves-Edouard Herpe; Abderrahmane Bengrine; Sandrine Belouzard; Czeslaw Wychowski; Jean Dubuisson; Catherine Francois; Jean-Marc Regimbeau; Sandrine Castelain; Gilles Duverlie
Journal:  PLoS One       Date:  2013-08-05       Impact factor: 3.240
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