Literature DB >> 22158354

Generation of the potent anti-malarial drug artemisinin in tobacco.

Moran Farhi, Elena Marhevka, Julius Ben-Ari, Anna Algamas-Dimantov, Zhuobin Liang, Vardit Zeevi, Orit Edelbaum, Ben Spitzer-Rimon, Hagai Abeliovich, Betty Schwartz, Tzvi Tzfira, Alexander Vainstein.   

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Year:  2011        PMID： 22158354     DOI： 10.1038/nbt.2054

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  16 in total

1.  The production of artemisinin precursors in tobacco.

Authors:  Yansheng Zhang; Goska Nowak; Darwin W Reed; Patrick S Covello
Journal:  Plant Biotechnol J       Date:  2010-08-18       Impact factor: 9.803

2.  Making artemisinin.

Authors:  Patrick S Covello
Journal:  Phytochemistry       Date:  2008-11-01       Impact factor: 4.072

Review 3.  When more is better: multigene engineering in plants.

Authors:  Shaista Naqvi; Gemma Farré; Georgina Sanahuja; Teresa Capell; Changfu Zhu; Paul Christou
Journal:  Trends Plant Sci       Date:  2009-10-21       Impact factor: 18.313

4.  Harnessing yeast subcellular compartments for the production of plant terpenoids.

Authors:  Moran Farhi; Elena Marhevka; Tania Masci; Evgeniya Marcos; Yoram Eyal; Mariana Ovadis; Hagai Abeliovich; Alexander Vainstein
Journal:  Metab Eng       Date:  2011-05-18       Impact factor: 9.783

5.  Production of the antimalarial drug precursor artemisinic acid in engineered yeast.

Authors:  Dae-Kyun Ro; Eric M Paradise; Mario Ouellet; Karl J Fisher; Karyn L Newman; John M Ndungu; Kimberly A Ho; Rachel A Eachus; Timothy S Ham; James Kirby; Michelle C Y Chang; Sydnor T Withers; Yoichiro Shiba; Richmond Sarpong; Jay D Keasling
Journal:  Nature       Date:  2006-04-13       Impact factor: 49.962

6.  Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways.

Authors:  Melissa J Towler; Pamela J Weathers
Journal:  Plant Cell Rep       Date:  2007-08-21       Impact factor: 4.570

7.  Nicotiana benthamiana as a production platform for artemisinin precursors.

Authors:  Teun W J M van Herpen; Katarina Cankar; Marilise Nogueira; Dirk Bosch; Harro J Bouwmeester; Jules Beekwilder
Journal:  PLoS One       Date:  2010-12-03       Impact factor: 3.240

8.  Artemisinin biosynthesis in growing plants of Artemisia annua. A 13CO2 study.

Authors:  Nicholas Schramek; Huahong Wang; Werner Römisch-Margl; Birgit Keil; Tanja Radykewicz; Bernhard Winzenhörlein; Ludger Beerhues; Adelbert Bacher; Felix Rohdich; Jonathan Gershenzon; Benye Liu; Wolfgang Eisenreich
Journal:  Phytochemistry       Date:  2009-11-22       Impact factor: 4.072

Review 9.  Microbially derived artemisinin: a biotechnology solution to the global problem of access to affordable antimalarial drugs.

Authors:  Victoria Hale; Jay D Keasling; Neil Renninger; Thierry T Diagana
Journal:  Am J Trop Med Hyg       Date:  2007-12       Impact factor: 2.345

10.  The molecular cloning of artemisinic aldehyde Delta11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua.

Authors:  Yansheng Zhang; Keat H Teoh; Darwin W Reed; Lies Maes; Alain Goossens; Douglas J H Olson; Andrew R S Ross; Patrick S Covello
Journal:  J Biol Chem       Date:  2008-05-21       Impact factor: 5.157
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  40 in total

1.  Metabolic engineering of chloroplasts for artemisinic acid biosynthesis and impact on plant growth.

Authors:  Bhawna Saxena; Mayavan Subramaniyan; Karan Malhotra; Neel Sarovar Bhavesh; Shobha Devi Potlakayala; Shashi Kumar
Journal:  J Biosci       Date:  2014-03       Impact factor: 1.826

Review 2.  Harnessing evolutionary diversification of primary metabolism for plant synthetic biology.

Authors:  Hiroshi A Maeda
Journal:  J Biol Chem       Date:  2019-09-26       Impact factor: 5.157

3.  Compartmentalized Metabolic Engineering for Artemisinin Biosynthesis and Effective Malaria Treatment by Oral Delivery of Plant Cells.

Authors:  Karan Malhotra; Mayavan Subramaniyan; Khushboo Rawat; Md Kalamuddin; M Irfan Qureshi; Pawan Malhotra; Asif Mohmmed; Katrina Cornish; Henry Daniell; Shashi Kumar
Journal:  Mol Plant       Date:  2016-10-20       Impact factor: 13.164

Review 4.  Plant Glandular Trichomes: Natural Cell Factories of High Biotechnological Interest.

Authors:  Alexandre Huchelmann; Marc Boutry; Charles Hachez
Journal:  Plant Physiol       Date:  2017-07-19       Impact factor: 8.340

5.  Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants.

Authors:  Laura K Henry; Michael Gutensohn; Suzanne T Thomas; Joseph P Noel; Natalia Dudareva
Journal:  Proc Natl Acad Sci U S A       Date:  2015-07-27       Impact factor: 11.205

6.  Proteomic analysis of Artemisia annua--towards elucidating the biosynthetic pathways of the antimalarial pro-drug artemisinin.

Authors:  Laura Bryant; Brian Flatley; Chhaya Patole; Geoffrey D Brown; Rainer Cramer
Journal:  BMC Plant Biol       Date:  2015-07-09       Impact factor: 4.215

7.  An enzymatic platform for the synthesis of isoprenoid precursors.

Authors:  Sofia B Rodriguez; Thomas S Leyh
Journal:  PLoS One       Date:  2014-08-25       Impact factor: 3.240

Review 8.  Discovery and resupply of pharmacologically active plant-derived natural products: A review.

Authors:  Atanas G Atanasov; Birgit Waltenberger; Eva-Maria Pferschy-Wenzig; Thomas Linder; Christoph Wawrosch; Pavel Uhrin; Veronika Temml; Limei Wang; Stefan Schwaiger; Elke H Heiss; Judith M Rollinger; Daniela Schuster; Johannes M Breuss; Valery Bochkov; Marko D Mihovilovic; Brigitte Kopp; Rudolf Bauer; Verena M Dirsch; Hermann Stuppner
Journal:  Biotechnol Adv       Date:  2015-08-15       Impact factor: 14.227

Review 9.  Molecular Farming in Artemisia annua, a Promising Approach to Improve Anti-malarial Drug Production.

Authors:  Giuseppe Pulice; Soraya Pelaz; Luis Matías-Hernández
Journal:  Front Plant Sci       Date:  2016-03-18       Impact factor: 5.753

10.  Key applications of plant metabolic engineering.

Authors:  Warren Lau; Michael A Fischbach; Anne Osbourn; Elizabeth S Sattely
Journal:  PLoS Biol       Date:  2014-06-10       Impact factor: 8.029
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