Literature DB >> 22157871

Dysregulation of mTOR signaling in neuropsychiatric disorders: therapeutic implications.

Kirsty Sawicka1, R Suzanne Zukin.   

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Year:  2012        PMID： 22157871      PMCID： PMC3238083          DOI： 10.1038/npp.2011.210

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


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  6 in total

1.  Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.

Authors:  Christina Gross; Mika Nakamoto; Xiaodi Yao; Chi-Bun Chan; So Y Yim; Keqiang Ye; Stephen T Warren; Gary J Bassell
Journal:  J Neurosci       Date:  2010-08-11       Impact factor: 6.167

2.  Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.

Authors:  Dan Ehninger; Sangyeul Han; Carrie Shilyansky; Yu Zhou; Weidong Li; David J Kwiatkowski; Vijaya Ramesh; Alcino J Silva
Journal:  Nat Med       Date:  2008-06-22       Impact factor: 53.440

3.  Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice.

Authors:  Jing Zhou; Jacqueline Blundell; Shiori Ogawa; Chang-Hyuk Kwon; Wei Zhang; Christopher Sinton; Craig M Powell; Luis F Parada
Journal:  J Neurosci       Date:  2009-02-11       Impact factor: 6.167

4.  Dysregulation of mTOR signaling in fragile X syndrome.

Authors:  Ali Sharma; Charles A Hoeffer; Yukihiro Takayasu; Takahiro Miyawaki; Sean M McBride; Eric Klann; R Suzanne Zukin
Journal:  J Neurosci       Date:  2010-01-13       Impact factor: 6.167

Review 5.  Advances in autism genetics: on the threshold of a new neurobiology.

Authors:  Brett S Abrahams; Daniel H Geschwind
Journal:  Nat Rev Genet       Date:  2008-05       Impact factor: 53.242

6.  FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Authors:  Jennifer C Darnell; Sarah J Van Driesche; Chaolin Zhang; Ka Ying Sharon Hung; Aldo Mele; Claire E Fraser; Elizabeth F Stone; Cynthia Chen; John J Fak; Sung Wook Chi; Donny D Licatalosi; Joel D Richter; Robert B Darnell
Journal:  Cell       Date:  2011-07-22       Impact factor: 41.582
  6 in total
  20 in total

1.  Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.

Authors:  Guomei Tang; Kathryn Gudsnuk; Sheng-Han Kuo; Marisa L Cotrina; Gorazd Rosoklija; Alexander Sosunov; Mark S Sonders; Ellen Kanter; Candace Castagna; Ai Yamamoto; Zhenyu Yue; Ottavio Arancio; Bradley S Peterson; Frances Champagne; Andrew J Dwork; James Goldman; David Sulzer
Journal:  Neuron       Date:  2014-08-21       Impact factor: 17.173

2.  Autism genes keep turning up chromatin.

Authors:  Janine M Lasalle
Journal:  OA Autism       Date:  2013-06-19

3.  Bidirectional manipulation of mTOR signaling disrupts socially mediated vocal learning in juvenile songbirds.

Authors:  Somayeh Ahmadiantehrani; Sarah E London
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-24       Impact factor: 11.205

4.  A New Link Between Insulin Signaling and Fragile X Syndrome.

Authors:  Bei Bu; Luoying Zhang
Journal:  Neurosci Bull       Date:  2016-11-12       Impact factor: 5.203

Review 5.  Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism.

Authors:  Kimberly M Huber; Eric Klann; Mauro Costa-Mattioli; R Suzanne Zukin
Journal:  J Neurosci       Date:  2015-10-14       Impact factor: 6.167

6.  JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.

Authors:  Jamee M Berg; Changhoon Lee; Leslie Chen; Laurie Galvan; Carlos Cepeda; Jane Y Chen; Olga Peñagarikano; Jason L Stein; Alvin Li; Asami Oguro-Ando; Jeremy A Miller; Ajay A Vashisht; Mary E Starks; Elyse P Kite; Eric Tam; Amos Gdalyahu; Noor B Al-Sharif; Zachary D Burkett; Stephanie A White; Scott C Fears; Michael S Levine; James A Wohlschlegel; Daniel H Geschwind
Journal:  Neuron       Date:  2015-11-25       Impact factor: 17.173

7.  Insulin-Like Growth Factor II Targets the mTOR Pathway to Reverse Autism-Like Phenotypes in Mice.

Authors:  Adam B Steinmetz; Sarah A Stern; Amy S Kohtz; Giannina Descalzi; Cristina M Alberini
Journal:  J Neurosci       Date:  2017-12-07       Impact factor: 6.167

8.  Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice.

Authors:  Kirsty Sawicka; Alexander Pyronneau; Miranda Chao; Michael V L Bennett; R Suzanne Zukin
Journal:  Proc Natl Acad Sci U S A       Date:  2016-09-23       Impact factor: 11.205

9.  Exploiting aberrant mRNA expression in autism for gene discovery and diagnosis.

Authors:  Jinting Guan; Ence Yang; Jizhou Yang; Yong Zeng; Guoli Ji; James J Cai
Journal:  Hum Genet       Date:  2016-04-30       Impact factor: 4.132

Review 10.  Learning and memory: an emergent property of cell motility.

Authors:  Michel Baudry; Xiaoning Bi
Journal:  Neurobiol Learn Mem       Date:  2013-05-21       Impact factor: 2.877
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