Literature DB >> 22156022

Monte Carlo simulation of energy-deposit clustering for ions of the same LET in liquid water.

Z Francis1, S Incerti, V Ivanchenko, C Champion, M Karamitros, M A Bernal, Z El Bitar.   

Abstract

This work presents a Monte Carlo study of energy depositions due to protons, alpha particles and carbon ions of the same linear-energy-transfer (LET) in liquid water. The corresponding track structures were generated using the Geant4-DNA toolkit, and the energy deposition spatial distributions were analyzed using an adapted version of the DBSCAN clustering algorithm. Combining the Geant4 simulations and the clustering algorithm it was possible to compare the quality of the different radiation types. The ratios of clustered and single energy depositions are shown versus particle LET and frequency-mean lineal energies. The estimated effect of these types of radiation on biological tissues is then discussed by comparing the results obtained for different particles with the same LET.

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Year:  2012        PMID: 22156022     DOI: 10.1088/0031-9155/57/1/209

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  7 in total

1.  Microdosimetry of DNA conformations: relation between direct effect of (60)Co gamma rays and topology of DNA geometrical models in the calculation of A-, B- and Z-DNA radiation-induced damage yields.

Authors:  Farid Semsarha; Gholamreza Raisali; Bahram Goliaei; Hossein Khalafi
Journal:  Radiat Environ Biophys       Date:  2016-03-16       Impact factor: 1.925

2.  The influence of Geant4-DNA toolkit parameters on electron microdosimetric track structure.

Authors:  Yidi Wang; Zhanpeng Li; Shuyuan Zhang; Wei Tang; Xiang Li; Dandan Chen; Liang Sun
Journal:  J Radiat Res       Date:  2020-01-23       Impact factor: 2.724

3.  Flagged uniform particle splitting for variance reduction in proton and carbon ion track-structure simulations.

Authors:  José Ramos-Méndez; Jan Schuemann; Sebastien Incerti; Harald Paganetti; Reinhard Schulte; Bruce Faddegon
Journal:  Phys Med Biol       Date:  2017-07-06       Impact factor: 3.609

4.  TOPAS-nBio: An Extension to the TOPAS Simulation Toolkit for Cellular and Sub-cellular Radiobiology.

Authors:  J Schuemann; A L McNamara; J Ramos-Méndez; J Perl; K D Held; H Paganetti; S Incerti; B Faddegon
Journal:  Radiat Res       Date:  2019-01-04       Impact factor: 2.841

5.  The Influence of DNA Configuration on the Direct Strand Break Yield.

Authors:  M A Bernal; C E deAlmeida; S Incerti; C Champion; V Ivanchenko; Z Francis
Journal:  Comput Math Methods Med       Date:  2015-06-01       Impact factor: 2.238

6.  Fast calculation of nanodosimetric quantities in treatment planning of proton and ion therapy.

Authors:  José Ramos-Méndez; Lucas N Burigo; Reinhard Schulte; Cynthia Chuang; Bruce Faddegon
Journal:  Phys Med Biol       Date:  2018-11-28       Impact factor: 3.609

7.  Circular Mitochondrial DNA: A Geant4-DNA User Application for Evaluating Radiation-induced Damage in Circular Mitochondrial DNA.

Authors:  Mohammad Bagher Tavakoli; Habiballah Moradi; Hossein Khanahmad; Mohsen Hosseini
Journal:  J Med Signals Sens       Date:  2017 Oct-Dec
  7 in total

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