Literature DB >> 22149726

Jewel of the seabed: sea cucumbers as nutritional and drug candidates.

Peck Loo Kiew1, Mashitah Mat Don.   

Abstract

Marine sources have been attracting the attention of scientists and manufacturers worldwide hoping to find new alternatives for biological active substances. Promising new research indicates that sea cucumber, which is slug-like in appearance and has been a staple in Japan, China and other parts of East Asia since ancient times, is beginning to gain popularity as a dietary supplement in western countries. The roles of sea cucumber extracts in various physiological functions have spurred researchers to investigate the ability of sea cucumber to be an alternative in neutraceutical and medical applications. This article provides a brief introduction to sea cucumber and reviews its numerous bioactive compounds, such as triterpene glycosides, glycosaminoglycans, gangliosides, collagen, branched-chain fatty acid and lectins, which serve as potential sources of neutraceutical, pharmaceutical and cosmetic agents, thus providing a new platform in biochemical research.

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Year:  2011        PMID: 22149726     DOI: 10.3109/09637486.2011.641944

Source DB:  PubMed          Journal:  Int J Food Sci Nutr        ISSN: 0963-7486            Impact factor:   3.833


  12 in total

1.  Probing the antioxidant activity of functional proteins and bioactive peptides in Hermetia illucens larvae fed with food wastes.

Authors:  Jiaxin Lu; Yuwen Guo; Atif Muhmood; Bei Zeng; Yizhan Qiu; Pan Wang; Lianhai Ren
Journal:  Sci Rep       Date:  2022-02-18       Impact factor: 4.379

2.  De novo genome assembly and annotation of Holothuria scabra (Jaeger, 1833) from nanopore sequencing reads.

Authors:  Honglin Luo; Guanghua Huang; Jianbin Li; Qiong Yang; Jiajie Zhu; Bin Zhang; Pengfei Feng; Yongde Zhang; Xueming Yang
Journal:  Genes Genomics       Date:  2022-10-16       Impact factor: 2.164

3.  Structure elucidation of five novel isomeric saponins from the viscera of the sea cucumber Holothuria lessoni.

Authors:  Yadollah Bahrami; Wei Zhang; Tim Chataway; Chris Franco
Journal:  Mar Drugs       Date:  2014-08-08       Impact factor: 5.118

Review 4.  Marine Pharmacology in 2012-2013: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2017-08-29       Impact factor: 5.118

Review 5.  Northern Sea Cucumber (Cucumaria frondosa): A Potential Candidate for Functional Food, Nutraceutical, and Pharmaceutical Sector.

Authors:  Abul Hossain; Deepika Dave; Fereidoon Shahidi
Journal:  Mar Drugs       Date:  2020-05-22       Impact factor: 5.118

6.  Sea cucumber genome provides insights into saponin biosynthesis and aestivation regulation.

Authors:  Yuli Li; Ruijia Wang; Xiaogang Xun; Jing Wang; Lisui Bao; Ramesha Thimmappa; Jun Ding; Jingwei Jiang; Liheng Zhang; Tianqi Li; Jia Lv; Chuang Mu; Xiaoli Hu; Lingling Zhang; Jing Liu; Yuqiang Li; Lijie Yao; Wenqian Jiao; Yangfan Wang; Shanshan Lian; Zelong Zhao; Yaoyao Zhan; Xiaoting Huang; Huan Liao; Jia Wang; Hongzhen Sun; Xue Mi; Yu Xia; Qiang Xing; Wei Lu; Anne Osbourn; Zunchun Zhou; Yaqing Chang; Zhenmin Bao; Shi Wang
Journal:  Cell Discov       Date:  2018-06-26       Impact factor: 38.079

7.  Effects of processing method on chemical compositions and nutritional quality of ready-to-eat sea cucumber (Apostichopus japonicus).

Authors:  Meng Li; Yanxia Qi; Lin Mu; Zhibo Li; Qiancheng Zhao; Jing Sun; Qinghua Jiang
Journal:  Food Sci Nutr       Date:  2019-01-22       Impact factor: 2.863

8.  Diterpene glycosides from Holothuria scabra exert the α-synuclein degradation and neuroprotection against α-synuclein-Mediated neurodegeneration in C. elegans model.

Authors:  Pawanrat Chalorak; Nilubon Sornkaew; Preeyanuch Manohong; Nakorn Niamnont; Nawaphat Malaiwong; Tanapol Limboonreung; Prasert Sobhon; Michael Aschner; Krai Meemon
Journal:  J Ethnopharmacol       Date:  2021-06-17       Impact factor: 5.195

Review 9.  Acetylated Triterpene Glycosides and Their Biological Activity from Holothuroidea Reported in the Past Six Decades.

Authors:  Yadollah Bahrami; Christopher M M Franco
Journal:  Mar Drugs       Date:  2016-08-04       Impact factor: 5.118

10.  Anti-proliferative and anti-inflammatory activities of the sea cucumber Holothuria polii aqueous extract.

Authors:  Mike Kareh; Rana El Nahas; Lamis Al-Aaraj; Sara Al-Ghadban; Nataly Naser Al Deen; Najat Saliba; Marwan El-Sabban; Rabih Talhouk
Journal:  SAGE Open Med       Date:  2018-11-02
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