| Literature DB >> 22149630 |
David J Moser1, Laura L Boles Ponto, Ivy N Miller, Susan K Schultz, Yusuf Menda, Stephan Arndt, Peggy C Nopoulos.
Abstract
This study was designed to determine the relationships between positron emission tomography (PET)-based quantitative measures of cerebral blood flow and cerebrovascular reserve and neuropsychological functioning in elderly individuals with atherosclerotic vascular disease. It was hypothesized that cerebrovascular function would be significantly associated with neuropsychological functioning. Results showed that both baseline global cerebral blood flow and cerebrovascular reserve were significantly associated with global neuropsychological functioning, when controlling for age and sex. Cerebrovascular reserve was additionally associated with performance on measures of memory and attention. Additional research is needed to determine whether measures of cerebral blood flow can be used to predict cognitive decline.Entities:
Mesh:
Year: 2011 PMID: 22149630 PMCID: PMC3582376 DOI: 10.1080/13803395.2011.630653
Source DB: PubMed Journal: J Clin Exp Neuropsychol ISSN: 1380-3395 Impact factor: 2.475