Literature DB >> 22143445

[Hypoxia is a key factor in the inflammatory milieu of rheumatic diseases].

M Hahne1, T Gaber, F Buttgereit.   

Abstract

Chronic inflammatory diseases are characterized by hypoxia and subsequent cellular adaptation via hypoxia-inducible factor (HIF). Modulation of these adaptation mechanisms provides the basis for ideas on how to improve the effects of known drugs and for the development of novel therapeutic approaches.

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Mesh:

Year:  2012        PMID: 22143445     DOI: 10.1007/s00393-011-0782-x

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  9 in total

Review 1.  Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors.

Authors:  Michail Sitkovsky; Dmitriy Lukashev
Journal:  Nat Rev Immunol       Date:  2005-09       Impact factor: 53.106

Review 2.  Hypoxia regulates macrophage functions in inflammation.

Authors:  Craig Murdoch; Munitta Muthana; Claire E Lewis
Journal:  J Immunol       Date:  2005-11-15       Impact factor: 5.422

Review 3.  Review: hypoxia-inducible factor-1 (HIF-1): a novel transcription factor in immune reactions.

Authors:  Thomas Hellwig-Bürgel; Daniel P Stiehl; Anika E Wagner; Eric Metzen; Wolfgang Jelkmann
Journal:  J Interferon Cytokine Res       Date:  2005-06       Impact factor: 2.607

Review 4.  Hypoxia inducible factor (HIF) in rheumatology: low O2! See what HIF can do!

Authors:  T Gaber; R Dziurla; R Tripmacher; G R Burmester; F Buttgereit
Journal:  Ann Rheum Dis       Date:  2005-03-30       Impact factor: 19.103

5.  Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1 alpha function and differentially influences human CD4+ T cell proliferation under hypoxia.

Authors:  Timo Gaber; Saskia Schellmann; Kerem B Erekul; Monique Fangradt; Karolina Tykwinska; Martin Hahne; Patrick Maschmeyer; Markus Wagegg; Cindy Stahn; Paula Kolar; René Dziurla; Max Löhning; Gerd-Rüdiger Burmester; Frank Buttgereit
Journal:  J Immunol       Date:  2010-12-17       Impact factor: 5.422

6.  Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.

Authors:  Eric V Dang; Joseph Barbi; Huang-Yu Yang; Dilini Jinasena; Hong Yu; Ying Zheng; Zachary Bordman; Juan Fu; Young Kim; Hung-Rong Yen; Weibo Luo; Karen Zeller; Larissa Shimoda; Suzanne L Topalian; Gregg L Semenza; Chi V Dang; Drew M Pardoll; Fan Pan
Journal:  Cell       Date:  2011-08-25       Impact factor: 41.582

Review 7.  Hypoxia-adenosinergic immunosuppression: tumor protection by T regulatory cells and cancerous tissue hypoxia.

Authors:  Michail V Sitkovsky; Jorgen Kjaergaard; Dmitriy Lukashev; Akio Ohta
Journal:  Clin Cancer Res       Date:  2008-10-01       Impact factor: 12.531

8.  IL-17A expression is localised to both mononuclear and polymorphonuclear synovial cell infiltrates.

Authors:  Ellen M Moran; René Heydrich; Chin Teck Ng; Tajvur P Saber; Jennifer McCormick; Joachim Sieper; Heiner Appel; Ursula Fearon; Douglas J Veale
Journal:  PLoS One       Date:  2011-08-24       Impact factor: 3.240

9.  Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.

Authors:  David R Mole; Christine Blancher; Richard R Copley; Patrick J Pollard; Jonathan M Gleadle; Jiannis Ragoussis; Peter J Ratcliffe
Journal:  J Biol Chem       Date:  2009-04-21       Impact factor: 5.157

  9 in total

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