Literature DB >> 22143419

Cholecystectomy in the very elderly--is 90 the new 70?

Attila Dubecz1, Miriam Langer, Rudolf J Stadlhuber, Michael Schweigert, Norbert Solymosi, Marcus Feith, Hubert J Stein.   

Abstract

BACKGROUND: Nonagenarians are the fastest growing sector of population across Western Europe. Although prevalence of gallstone disease is high, elective cholecystectomy is still controversial in this age group.
METHODS: A retrospective chart review was conducted of cholecystectomies done in patients over 90 years of age at our institution between 2004 and December 2009. During this period, a total of 3,009 cholecystectomies were performed on patients of all ages. Data collected included demographics, patient comorbidities, indications for surgery, type of surgery performed, intraoperative findings, histology, perioperative morbidity and mortality.
RESULTS: Twenty-two nonagenarians (18 females) underwent cholecystectomy during the study period. Of these patients, 19 patients (86%) had diabetes, 16 (73%) had hypertension, and 10 (45%) had coronary artery disease. Twenty patients (91%) underwent an emergency procedure. In two patients, cholecystectomy was indicated for non-resolving pain after attempted conservative therapy, only two patients were operated electively. Laparoscopic cholecystectomy was attempted in 13 patients (59%), 3 patients needed a conversion, and 9 patients (41%) considered unfit to undergo a laparoscopic approach had an open procedure. Mean operation time was 83 min. Histology showed gangrenous cholecystitis in six (27%) patients. The mean length of stay was 10 days (4-23 days). Two patients (8.3%) required intensive care following surgery. There were no common bile duct injuries, one patient had a cystic stump leak. One patient died in the postoperative period (4.6%). All patients with an emergency operation were classified as at least ASA III. Conversion rate, percentage of open procedures, percentage of advanced histology, ASA score, and hospital stay were significantly higher when compared to all patients.
CONCLUSION: Our study demonstrates that in unselected nonagenarians,cholecystectomy is safe with acceptable perioperative morbidity and mortality even as an emergency procedure. However, our data also suggests that cholecystitis appears to be a neglected condition in this age group.

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Year:  2011        PMID: 22143419     DOI: 10.1007/s11605-011-1708-2

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  17 in total

1.  Abdominal surgery in nonagenarians: short-term results.

Authors:  Juan J Arenal; Gustavo de Teresa; Claudia Tinoco; Miguel Toledano; Awwad Said
Journal:  Surg Today       Date:  2007-11-26       Impact factor: 2.549

2.  Hospital mortality after urgent and emergency laparotomy in patients aged 65 yr and over. Risk and prediction of risk using multiple logistic regression analysis.

Authors:  T M Cook; C J Day
Journal:  Br J Anaesth       Date:  1998-06       Impact factor: 9.166

3.  Randomized clinical trial of open versus laparoscopic cholecystectomy in the treatment of acute cholecystitis.

Authors:  M Johansson; A Thune; L Nelvin; M Stiernstam; B Westman; L Lundell
Journal:  Br J Surg       Date:  2005-01       Impact factor: 6.939

4.  Laparoscopic cholecystectomy in octogenarians.

Authors:  D Hazzan; N Geron; D Golijanin; P Reissman; E Shiloni
Journal:  Surg Endosc       Date:  2003-03-06       Impact factor: 4.584

Review 5.  Open, small-incision, or laparoscopic cholecystectomy for patients with symptomatic cholecystolithiasis. An overview of Cochrane Hepato-Biliary Group reviews.

Authors:  Frederik Keus; Hein G Gooszen; Cornelis Jhm van Laarhoven
Journal:  Cochrane Database Syst Rev       Date:  2010-01-20

6.  Factors determining conversion to laparotomy in patients undergoing laparoscopic cholecystectomy.

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7.  Results of colectomy in elderly patients with colon cancer, based on Medicare claims data.

Authors:  J Whittle; E P Steinberg; G F Anderson; R Herbert
Journal:  Am J Surg       Date:  1992-06       Impact factor: 2.565

8.  Randomised trial of laparoscopic versus open cholecystectomy for acute and gangrenous cholecystitis.

Authors:  T Kiviluoto; J Sirén; P Luukkonen; E Kivilaakso
Journal:  Lancet       Date:  1998-01-31       Impact factor: 79.321

9.  Risk factors in elective laparoscopic cholecystectomy for conversion to open cholecystectomy.

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Journal:  J Am Coll Surg       Date:  1994-12       Impact factor: 6.113

10.  The prevalence of gallstone disease in very old institutionalized persons.

Authors:  J Ratner; A Lisbona; M Rosenbloom; M Palayew; S Szabolcsi; T Tupaz
Journal:  JAMA       Date:  1991-02-20       Impact factor: 56.272

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  13 in total

1.  Laparoscopic vs open partial colectomy in elderly patients: Insights from the American College of Surgeons - National Surgical Quality Improvement Program database.

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Journal:  World J Gastroenterol       Date:  2015-12-07       Impact factor: 5.742

2.  The risk paradox: use of elective cholecystectomy in older patients is independent of their risk of developing complications.

Authors:  Taylor S Riall; Deepak Adhikari; Abhishek D Parmar; Suzanne K Linder; Francesca M Dimou; Winston Crowell; Nina P Tamirisa; Courtney M Townsend; James S Goodwin
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3.  Are They Too Old for Surgery? Safety of Cholecystectomy in Superelderly Patients (≥ Age 90).

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Journal:  Perm J       Date:  2017

Review 4.  The Treatment of Critically Ill Patients With Acute Cholecystitis.

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Journal:  Dtsch Arztebl Int       Date:  2016-08-22       Impact factor: 5.594

5.  Surgical management of empyematous cholecystitis: a register study of over 12,000 cases from a regional quality control database in Germany.

Authors:  Peter C Ambe; Stefan Jansen; Susanne Macher-Heidrich; Hubert Zirngibl
Journal:  Surg Endosc       Date:  2016-05-13       Impact factor: 4.584

6.  How Safe is Performing Cholecystectomy in the Oldest Old? A 15-year Retrospective Study from a Single Institution.

Authors:  Matteo Novello; Davide Gori; Salomone Di Saverio; Matteo Bianchin; Lorenzo Maestri; Francesco Vito Mandarino; Giuseppe Cavallari; Bruno Nardo
Journal:  World J Surg       Date:  2018-01       Impact factor: 3.352

7.  PREOP-Gallstones: A Prognostic Nomogram for the Management of Symptomatic Cholelithiasis in Older Patients.

Authors:  Abhishek D Parmar; Kristin M Sheffield; Deepak Adhikari; Robert A Davee; Gabriela M Vargas; Nina P Tamirisa; Yong-Fang Kuo; James S Goodwin; Taylor S Riall
Journal:  Ann Surg       Date:  2015-06       Impact factor: 12.969

8.  Time trend and variability of open versus laparoscopic cholecystectomy in patients with symptomatic gallstone disease.

Authors:  Mario Saia; Domenico Mantoan; Alessandra Buja; Chiara Bertoncello; Tatjana Baldovin; Giampietro Callegaro; Vincenzo Baldo
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9.  Therapeutic experience of 289 elderly patients with biliary diseases.

Authors:  Zong-Ming Zhang; Zhuo Liu; Li-Min Liu; Chong Zhang; Hong-Wei Yu; Bai-Jiang Wan; Hai Deng; Ming-Wen Zhu; Zi-Xu Liu; Wen-Ping Wei; Meng-Meng Song; Yue Zhao
Journal:  World J Gastroenterol       Date:  2017-04-07       Impact factor: 5.742

10.  Acute Cholecystitis in Very Elderly Patients: Disease Management, Outcomes, and Risk Factors for Complications.

Authors:  Alfredo Escartín; Marta González; Elena Cuello; Ana Pinillos; Pablo Muriel; Mireia Merichal; Victor Palacios; Jordi Escoll; Cristina Gas; Jorge-Juan Olsina
Journal:  Surg Res Pract       Date:  2019-02-03
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