BACKGROUND: The hepatitis C virus (HCV) genomic database is expanding rapidly. AIMS: There is a need to provide an updated phylogenetic tree analysis based on the complete coding region of HCV. METHODS: All available HCV complete genome sequences in the HCV databases available through October 2010 were analyzed. RESULTS: The assignment of all known complete sequences up-to-date confirmed the previous six major genotypes and one new sequence, which have been provisionally assigned as subtype 7a. New recombinant forms of HCV, although uncommon, have been detected and were found to have different crossover points. CONCLUSION: This updated analysis based on the complete region of HCV confirmed the validity of the previously assigned genotypes/subtypes and provided an up-to-date reference for future basic research and clinical studies.
BACKGROUND: The hepatitis C virus (HCV) genomic database is expanding rapidly. AIMS: There is a need to provide an updated phylogenetic tree analysis based on the complete coding region of HCV. METHODS: All available HCV complete genome sequences in the HCV databases available through October 2010 were analyzed. RESULTS: The assignment of all known complete sequences up-to-date confirmed the previous six major genotypes and one new sequence, which have been provisionally assigned as subtype 7a. New recombinant forms of HCV, although uncommon, have been detected and were found to have different crossover points. CONCLUSION: This updated analysis based on the complete region of HCV confirmed the validity of the previously assigned genotypes/subtypes and provided an up-to-date reference for future basic research and clinical studies.
Authors: Andrew Kohlway; Nathan Pirakitikulr; Francisco N Barrera; Olga Potapova; Donald M Engelman; Anna M Pyle; Brett D Lindenbach Journal: J Virol Date: 2013-10-30 Impact factor: 5.103
Authors: Jason Alexander Ji-Xhin Wong; Rakesh Bhat; Darren Hockman; Michael Logan; Chao Chen; Aviad Levin; Sharon E Frey; Robert B Belshe; D Lorne Tyrrell; John Lok Man Law; Michael Houghton Journal: J Virol Date: 2014-10-01 Impact factor: 5.103
Authors: Donald G Murphy; Erwin Sablon; Jasmine Chamberland; Eric Fournier; Raymond Dandavino; Cécile L Tremblay Journal: J Clin Microbiol Date: 2014-12-17 Impact factor: 5.948
Authors: Andrew Kohlway; Nathan Pirakitikulr; Steve C Ding; Feng Yang; Dahai Luo; Brett D Lindenbach; Anna M Pyle Journal: J Virol Date: 2014-06-25 Impact factor: 5.103