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Literature DB >> 22139511

Primordial ocean chemistry and its compatibility with the RNA world.

Abstract

We examine the stability of three key components needed to establish an RNA World under a range of potential conditions present on the early earth. The stability of ribose, cytosine, and the phosphodiester bond are estimated at different pH values and temperatures by extrapolating available experimental data. The conditions we have chosen range from highly acidic or alkaline hydrothermal vents, to the milder conditions in a primordial ocean at a range of atmospheric CO(2) partial pressures.

Entities: Chemical

Mesh：

Substances：
RNA
Ribose
Cytosine

Year: 2011 PMID： 22139511 DOI： 10.1007/s11084-011-9250-5

Source DB: PubMed Journal: Orig Life Evol Biosph ISSN： 0169-6149 Impact factor: 1.950

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2. Origin of the RNA world: The fate of nucleobases in warm little ponds.

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3. A Proposal of the Ur-proteome.

Authors: Miryam Palacios-Pérez; Fernando Andrade-Díaz; Marco V José
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4. Purine biosynthetic intermediate-containing ribose-phosphate polymers as evolutionary precursors to RNA.

Authors: Harold S Bernhardt; Roger K Sandwick
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5. On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution.

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