Literature DB >> 22136483

Evaluation of IL18 and IL18R1 polymorphisms: genetic susceptibility to knee osteoarthritis.

S L Hulin-Curtis1, J L Bidwell, M J Perry.   

Abstract

We examined single-nucleotide polymorphisms (SNPs) in IL18 and IL18/R1 genes and knee OA. IL18 rs1946518 wild-type allele was more frequently observed in cases (P = 0.04). Haplotype 1 was more frequently observed in cases (P = 0.04). Genetic variation in the promoter region of IL18, but not IL18R1, may be associated with OA.
© 2011 Blackwell Publishing Ltd.

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Year:  2011        PMID： 22136483     DOI： 10.1111/j.1744-313X.2011.01060.x

Source DB:  PubMed          Journal:  Int J Immunogenet        ISSN： 1744-3121            Impact factor:   1.466


  3 in total

1.  Genetic polymorphisms of interleukin-16 and risk of knee osteoarthritis.

Authors:  Shi-Xing Luo; Shan Li; Xue-Hui Zhang; Jun-Jing Zhang; Guang-Hua Long; Gui-Fu Dong; Wei Su; Yan Deng; Yanqiong Liu; Jin-Min Zhao; Xue Qin
Journal:  PLoS One       Date:  2015-05-08       Impact factor: 3.240

2.  Identification of novel genetic variations affecting osteoarthritis patients.

Authors:  Mamdooh Abdullah Gari; Mohammed AlKaff; Haneen S Alsehli; Ashraf Dallol; Abdullah Gari; Muhammad Abu-Elmagd; Roaa Kadam; Mohammed F Abuzinadah; Mazin Gari; Adel M Abuzenadah; Kalamegam Gauthaman; Heba Alkhatabi; Mohammed M Abbas
Journal:  BMC Med Genet       Date:  2016-10-10       Impact factor: 2.103

Review 3.  The role of inflammatory and anti-inflammatory cytokines in the pathogenesis of osteoarthritis.

Authors:  Piotr Wojdasiewicz; Łukasz A Poniatowski; Dariusz Szukiewicz
Journal:  Mediators Inflamm       Date:  2014-04-30       Impact factor: 4.711
  3 in total

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