Literature DB >> 2213084

Risk ratios and risk differences in estimating the effect of risk factors for cardiovascular disease in the elderly.

B M Psaty1, T D Koepsell, T A Manolio, W T Longstreth, E H Wagner, P W Wahl, R A Kronmal.   

Abstract

This article reviews the nature of the effects of hypertension, smoking and cholesterol on the incidence of cardiovascular disease and emphasizes how these effects vary by age. In the Methods section, we discuss briefly the concepts of additive and multiplicative statistical models as tools for summarizing data. In the results section, we summarize available data on the association between incident stroke and coronary heart disease in the elderly and each of these major risk factors. The traditional multiplicative model parsimoniously characterizes the individual and joint effects of age and high blood pressure in terms of risk ratios; but, for smoking and cholesterol, an additive model appears to be the most parsimonious. We discuss the consequences of these observations for the study and prevention of cardiovascular disease in the elderly.

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Year:  1990        PMID: 2213084     DOI: 10.1016/0895-4356(90)90079-5

Source DB:  PubMed          Journal:  J Clin Epidemiol        ISSN: 0895-4356            Impact factor:   6.437


  10 in total

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Review 2.  Differences between studies in reported relative risks associated with smoking: an overview.

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3.  Variation between studies in reported relative risks associated with hypertension: time trends and other explanatory variables.

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4.  Assessing the effectiveness of health interventions for cost-effectiveness analysis. Panel on Cost-Effectiveness in Health and Medicine.

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5.  Patterns of Cardiovascular Risk Factors in Old Age and Survival and Health Status at 90.

Authors:  Michelle C Odden; Andreea M Rawlings; Alice M Arnold; Mary Cushman; Mary L Biggs; Bruce M Psaty; Anne B Newman
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2020-10-15       Impact factor: 6.053

6.  Heterogeneous Exposure Associations in Observational Cohort Studies: The Example of Blood Pressure in Older Adults.

Authors:  Michelle C Odden; Andreea M Rawlings; Abtin Khodadadi; Xiaoli Fern; Michael G Shlipak; Kirsten Bibbins-Domingo; Kenneth Covinsky; Alka M Kanaya; Anne Lee; Mary N Haan; Anne B Newman; Bruce M Psaty; Carmen A Peralta
Journal:  Am J Epidemiol       Date:  2020-01-31       Impact factor: 4.897

7.  Subclinical hypothyroidism and risk for incident myocardial infarction among postmenopausal women.

Authors:  Vicky A LeGrys; Michele Jonsson Funk; Carol E Lorenz; Ayush Giri; Rebecca D Jackson; JoAnn E Manson; Robin Schectman; Todd L Edwards; Gerardo Heiss; Katherine E Hartmann
Journal:  J Clin Endocrinol Metab       Date:  2013-03-28       Impact factor: 5.958

8.  Decline of the relative risk of death associated with low employment grade at older age: the impact of age related differences in smoking, blood pressure and plasma cholesterol.

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9.  Associations between cigarette smoking and total mortality differ depending on serum concentrations of persistent organic pollutants among the elderly.

Authors:  Yu-Mi Lee; Sang-Geun Bae; Seon-Hwa Lee; David R Jacobs; Duk-Hee Lee
Journal:  J Korean Med Sci       Date:  2013-07-31       Impact factor: 2.153

10.  Does mortality risk of cigarette smoking depend on serum concentrations of persistent organic pollutants? Prospective investigation of the vasculature in Uppsala seniors (PIVUS) study.

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Journal:  PLoS One       Date:  2014-05-14       Impact factor: 3.240

  10 in total

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