Literature DB >> 22125671

Risk profile and outcomes of aortic valve replacement in octogenarians.

Sujatha Kesavan1, Aamer Iqbal, Yusra Khan, Jonathan Hutter, Katie Pike, Chris Rogers, Mark Turner, Mandie Townsend, Andreas Baumbach.   

Abstract

AIM: To investigate the patient characteristics, relationship between the Logistic EuroSCORE (LES) and the observed outcomes in octogenarians who underwent surgical aortic valve replacement (AVR).
METHODS: Two hundred and seventy three octogenarians underwent AVR between 1996 and 2008 at Bristol Royal Infirmary. Demographics, acute outcomes, length of hospital stay and mortality were obtained. The LES was calculated to characterize the predicted operative risk. Two groups were defined: LES ≥ 15 (n = 80) and LES < 15 (n = 193).
RESULTS: In patients with LES ≥ 15, 30 d mortality was 14% (95% CI: 7%-23%) compared with 4% (95% CI: 2%-8%) in the LES < 15 group (P < 0.007). Despite the increase in number of operations from 1996 to 2008, the average LES did not change. Only 5% of patients had prior bypass surgery. The LES identified a low risk quartile of patients with a very low mortality (4%, n = 8, P < 0.007) at 30 d. The overall surgical results for octogenarians were excellent. The low risk group had an excellent outcome and the high risk group had a poor outcome after surgical AVR.
CONCLUSION: It may be better treated with transcatheter aortic valve implantation.

Entities:  

Keywords:  Aortic valve replacement; Coronary artery bypass grafting; Logistic EuroSCORE; Transcatheter aortic valve implantation

Year:  2011        PMID: 22125671      PMCID: PMC3224869          DOI: 10.4330/wjc.v3.i11.359

Source DB:  PubMed          Journal:  World J Cardiol


  20 in total

1.  Outcomes of cardiac surgery in patients > or = 80 years: results from the National Cardiovascular Network.

Authors:  K P Alexander; K J Anstrom; L H Muhlbaier; R D Grosswald; P K Smith; R H Jones; E D Peterson
Journal:  J Am Coll Cardiol       Date:  2000-03-01       Impact factor: 24.094

2.  Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery.

Authors:  Martin B Leon; Craig R Smith; Michael Mack; D Craig Miller; Jeffrey W Moses; Lars G Svensson; E Murat Tuzcu; John G Webb; Gregory P Fontana; Raj R Makkar; David L Brown; Peter C Block; Robert A Guyton; Augusto D Pichard; Joseph E Bavaria; Howard C Herrmann; Pamela S Douglas; John L Petersen; Jodi J Akin; William N Anderson; Duolao Wang; Stuart Pocock
Journal:  N Engl J Med       Date:  2010-09-22       Impact factor: 91.245

3.  High-risk aortic valve replacement: are the outcomes as bad as predicted?

Authors:  Eugene A Grossi; Charles F Schwartz; Pey-Jen Yu; Ulrich P Jorde; Gregory A Crooke; Juan B Grau; Greg H Ribakove; F Gregory Baumann; Patricia Ursumanno; Alfred T Culliford; Stephen B Colvin; Aubrey C Galloway
Journal:  Ann Thorac Surg       Date:  2008-01       Impact factor: 4.330

4.  Long-term outcomes after isolated aortic valve replacement in octogenarians: a modern perspective.

Authors:  Vinod H Thourani; Richard Myung; Patrick Kilgo; Karen Thompson; John D Puskas; Omar M Lattouf; William A Cooper; J David Vega; Edward P Chen; Robert A Guyton
Journal:  Ann Thorac Surg       Date:  2008-11       Impact factor: 4.330

5.  Thirty-day results of the SAPIEN aortic Bioprosthesis European Outcome (SOURCE) Registry: A European registry of transcatheter aortic valve implantation using the Edwards SAPIEN valve.

Authors:  Martyn Thomas; Gerhard Schymik; Thomas Walther; Dominique Himbert; Thierry Lefèvre; Hendrik Treede; Holger Eggebrecht; Paolo Rubino; Iassen Michev; Rüdiger Lange; William N Anderson; Olaf Wendler
Journal:  Circulation       Date:  2010-06-21       Impact factor: 29.690

Review 6.  Aortic valve replacement in the elderly: frequently indicated yet frequently denied.

Authors:  Katrina A Bramstedt
Journal:  Gerontology       Date:  2003 Jan-Feb       Impact factor: 5.140

7.  Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience.

Authors:  Josep Rodés-Cabau; John G Webb; Anson Cheung; Jian Ye; Eric Dumont; Christopher M Feindel; Mark Osten; Madhu K Natarajan; James L Velianou; Giuseppe Martucci; Benoît DeVarennes; Robert Chisholm; Mark D Peterson; Samuel V Lichtenstein; Fabian Nietlispach; Daniel Doyle; Robert DeLarochellière; Kevin Teoh; Victor Chu; Adrian Dancea; Kevin Lachapelle; Asim Cheema; David Latter; Eric Horlick
Journal:  J Am Coll Cardiol       Date:  2010-01-22       Impact factor: 24.094

Review 8.  Outcome after aortic valve replacement in octogenarians.

Authors:  Bruno Chiappini; Nicola Camurri; Antonio Loforte; Luca Di Marco; Roberto Di Bartolomeo; Giuseppe Marinelli
Journal:  Ann Thorac Surg       Date:  2004-07       Impact factor: 4.330

9.  Aortic valve replacement in octogenarians: risk factors for early and late mortality.

Authors:  Spencer J Melby; Andreas Zierer; Scott P Kaiser; Tracey J Guthrie; Jason D Keune; Richard B Schuessler; Michael K Pasque; Jennifer S Lawton; Nader Moazami; Marc R Moon; Ralph J Damiano
Journal:  Ann Thorac Surg       Date:  2007-05       Impact factor: 4.330

10.  Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis: device success and 30-day clinical outcome.

Authors:  Eberhard Grube; Gerhard Schuler; Lutz Buellesfeld; Ulrich Gerckens; Axel Linke; Peter Wenaweser; Barthel Sauren; Friedrich-Wilhelm Mohr; Thomas Walther; Bernfried Zickmann; Stein Iversen; Thomas Felderhoff; Raymond Cartier; Raoul Bonan
Journal:  J Am Coll Cardiol       Date:  2007-06-06       Impact factor: 24.094

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  4 in total

1.  Perspective on the cost-effectiveness of transapical aortic valve implantation in high-risk patients: Outcomes of a decision-analytic model.

Authors:  Hemal Gada; Shikhar Agarwal; Thomas H Marwick
Journal:  Ann Cardiothorac Surg       Date:  2012-07

2.  3D-echo in preoperative assessment of aortic cusps effective height.

Authors:  Jan Nijs; Sandro Gelsomino; Bastian Bljh Kietselaer; Orlando Parise; Fabiana Lucà; Jos G Maessen; Mark La Meir
Journal:  World J Cardiol       Date:  2014-07-26

3.  The early and long-term outcomes of coronary artery bypass grafting added to aortic valve replacement compared to isolated aortic valve replacement in elderly patients: a systematic review and meta-analysis.

Authors:  Stefano D'Alessandro; Domenico Tuttolomondo; Gurmeet Singh; Daniel Hernandez-Vaquero; Claudia Pattuzzi; Alan Gallingani; Francesco Maestri; Francesco Nicolini; Francesco Formica
Journal:  Heart Vessels       Date:  2022-05-09       Impact factor: 1.814

4.  The impact of coronary artery bypass grafting added to aortic valve replacement on long-term outcomes in octogenarian patients: a reconstructed time-to-event meta-analysis.

Authors:  Alan Gallingani; Stefano D'Alessandro; Gurmeet Singh; Daniel Hernandez-Vaquero; Mevlüt Çelik; Evelina Ceccato; Francesco Nicolini; Francesco Formica
Journal:  Interact Cardiovasc Thorac Surg       Date:  2022-07-09
  4 in total

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