BACKGROUND: Living donor kidney transplantation is a well-established method to reduce time on the waiting list. Although the laparoscopic donor nephrectomy has already been established worldwide, more than 80% of the living donor nephrectomies are performed as a traditional open donor nephrectomy in Germany. The aim of our study was to analyze perioperative data and long-term outcome of donors and recipients following open donor nephrectomy. METHODS: From February 2004 to July 2008, a total of 51 open donor nephrectomies were performed in Tuebingen University Hospital. Forty-five data of corresponding transplant donors and recipients were analyzed. The Kocak classification which provides a format to compare postoperative complications after living donor nephrectomy was used. RESULTS: Five-year graft survival was 100%. No intraoperative complications occurred. Postoperatively Grad I complications were observed in 10 donors (22.2%). In the long term no major complications occurred. Two donors (4.4%) had newly diagnosed hypertension and required antihypertensive medication. None of the donors developed proteinuria. Right-sided transabdominal donor nephrectomy was associated with a shorter mean hospital stay compared to left-sided lumbar nephrectomy. (7.8 ± 2.4 vs. 9.2 ± 1.8 days, p < 0.05). CONCLUSION: Open donor nephrectomy is a safe procedure with an excellent graft survival. Complication rates in our center are comparable to recent results in laparoscopic living donor nephrectomy. Therefore, the open donor nephrectomy remains important.
BACKGROUND: Living donor kidney transplantation is a well-established method to reduce time on the waiting list. Although the laparoscopic donor nephrectomy has already been established worldwide, more than 80% of the living donor nephrectomies are performed as a traditional open donor nephrectomy in Germany. The aim of our study was to analyze perioperative data and long-term outcome of donors and recipients following open donor nephrectomy. METHODS: From February 2004 to July 2008, a total of 51 open donor nephrectomies were performed in Tuebingen University Hospital. Forty-five data of corresponding transplant donors and recipients were analyzed. The Kocak classification which provides a format to compare postoperative complications after living donor nephrectomy was used. RESULTS: Five-year graft survival was 100%. No intraoperative complications occurred. Postoperatively Grad I complications were observed in 10 donors (22.2%). In the long term no major complications occurred. Two donors (4.4%) had newly diagnosed hypertension and required antihypertensive medication. None of the donors developed proteinuria. Right-sided transabdominal donor nephrectomy was associated with a shorter mean hospital stay compared to left-sided lumbar nephrectomy. (7.8 ± 2.4 vs. 9.2 ± 1.8 days, p < 0.05). CONCLUSION: Open donor nephrectomy is a safe procedure with an excellent graft survival. Complication rates in our center are comparable to recent results in laparoscopic living donor nephrectomy. Therefore, the open donor nephrectomy remains important.
Authors: Michael Neipp; Steffan Jackobs; Thomas Becker; Andreas Meyer zu Vilsendorf; Markus Winny; Rainer Lueck; Juergen Klempnauer; Björn Nashan Journal: Transplantation Date: 2004-11-15 Impact factor: 4.939
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Authors: Niels F M Kok; May Y Lind; Birgitta M E Hansson; Desiree Pilzecker; Ingrid R A M Mertens zur Borg; Ben C Knipscheer; Eric J Hazebroek; Ine M Dooper; Willem Weimar; Wim C J Hop; Eddy M M Adang; Gert Jan van der Wilt; Hendrik J Bonjer; Jordanus A van der Vliet; Jan N M IJzermans Journal: BMJ Date: 2006-07-17
Authors: Hassan N Ibrahim; Robert Foley; LiPing Tan; Tyson Rogers; Robert F Bailey; Hongfei Guo; Cynthia R Gross; Arthur J Matas Journal: N Engl J Med Date: 2009-01-29 Impact factor: 91.245
Authors: Edward H Chin; David Hazzan; Daniel M Herron; John N Gaetano; Scott A Ames; Jonathan S Bromberg; Michael Edye Journal: Surg Endosc Date: 2006-12-16 Impact factor: 3.453