Literature DB >> 22121095

Site-specific conjugation of ScFvs antibodies to nanoparticles by bioorthogonal strain-promoted alkyne-nitrone cycloaddition.

Miriam Colombo1, Silvia Sommaruga, Serena Mazzucchelli, Laura Polito, Paolo Verderio, Patrizia Galeffi, Fabio Corsi, Paolo Tortora, Davide Prosperi.   

Abstract

Particularly suitable: An N-terminal serine mutant of anti-HER2 scFv antibody was conjugated to polymer-coated magnetofluorescent nanoparticles by strain-promoted alkyne-nitrone cycloaddition. The resulting nanoparticles (see scheme) proved effective in targeting and labeling HER2-positive breast cancer cells.
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2011        PMID： 22121095     DOI： 10.1002/anie.201106775

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  15 in total

1.  Bioorthogonal Click Chemistry-Based Synthetic Cell Glue.

Authors:  Heebeom Koo; Myunghwan Choi; Eunha Kim; Sei Kwang Hahn; Ralph Weissleder; Seok Hyun Yun
Journal:  Small       Date:  2015-11-19       Impact factor: 13.281

2.  Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca2+ mobilization and the inflammatory activity of dendritic cells.

Authors:  Laura Marongiu; Francesca Mingozzi; Clara Cigni; Roberta Marzi; Marco Di Gioia; Massimiliano Garrè; Dario Parazzoli; Laura Sironi; Maddalena Collini; Reiko Sakaguchi; Takashi Morii; Mariacristina Crosti; Monica Moro; Stéphane Schurmans; Tiziano Catelani; Rany Rotem; Miriam Colombo; Stephen Shears; Davide Prosperi; Ivan Zanoni; Francesca Granucci
Journal:  Sci Signal       Date:  2021-03-30       Impact factor: 8.192

Review 3.  Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy.

Authors:  James C Knight; Bart Cornelissen
Journal:  Am J Nucl Med Mol Imaging       Date:  2014-03-20

4.  Optimization of photoactive protein Z for fast and efficient site-specific conjugation of native IgG.

Authors:  James Z Hui; Andrew Tsourkas
Journal:  Bioconjug Chem       Date:  2014-08-27       Impact factor: 4.774

5.  An evolved Mxe GyrA intein for enhanced production of fusion proteins.

Authors:  Carrie J Marshall; Vanessa A Grosskopf; Taylor J Moehling; Benjamin J Tillotson; Gregory J Wiepz; Nicholas L Abbott; Ronald T Raines; Eric V Shusta
Journal:  ACS Chem Biol       Date:  2014-11-24       Impact factor: 5.100

Review 6.  Recent advances in covalent, site-specific protein immobilization.

Authors:  Morten Meldal; Sanne Schoffelen
Journal:  F1000Res       Date:  2016-09-12

Review 7.  Application of click chemistry in nanoparticle modification and its targeted delivery.

Authors:  Gawon Yi; Jihwan Son; Jihye Yoo; Changhee Park; Heebeom Koo
Journal:  Biomater Res       Date:  2018-04-13

8.  Impact of semi-solid formulations on skin penetration of iron oxide nanoparticles.

Authors:  Umberto M Musazzi; Benedetta Santini; Francesca Selmin; Valentina Marini; Fabio Corsi; Raffaele Allevi; Anna M Ferretti; Davide Prosperi; Francesco Cilurzo; Miriam Colombo; Paola Minghetti
Journal:  J Nanobiotechnology       Date:  2017-02-17       Impact factor: 10.435

9.  Immobilization of carboxypeptidase from Sulfolobus solfataricus on magnetic nanoparticles improves enzyme stability and functionality in organic media.

Authors:  Silvia Sommaruga; Elisabetta Galbiati; Jesus Peñaranda-Avila; Chiara Brambilla; Paolo Tortora; Miriam Colombo; Davide Prosperi
Journal:  BMC Biotechnol       Date:  2014-09-05       Impact factor: 2.563

Review 10.  Kinugasa reactions in water: from green chemistry to bioorthogonal labelling.

Authors:  Mariya Chigrinova; Douglas A MacKenzie; Allison R Sherratt; Lawrence L W Cheung; John Paul Pezacki; Paul Pezacki
Journal:  Molecules       Date:  2015-04-16       Impact factor: 4.411
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