Jonathan P Shepherd1, Andrew J Feola, Steven D Abramowitch, Pamela A Moalli. 1. Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology and Reconstructive Pelvic Surgery, University of Pittsburgh Medical Center, 300 Halket St., Pittsburgh, PA 15213, USA. shepherdjp@upmc.edu
Abstract
INTRODUCTION AND HYPOTHESIS: Recently, numerous type I macroporous polypropylene vaginal meshes have been introduced into the market with little known of their differences. METHODS: Seven vaginal meshes were obtained and loaded to failure (n = 5/type). Additional cyclic loading determined permanent deformation with submaximal loading. RESULTS: The load elongation curves demonstrated a bilinear response with lower stiffness (N/mm), followed by higher stiffness. Ascend™ was the stiffest mesh in both regions of the load elongation curve (0.72 and 1.66 N/mm) with the lowest transition to higher stiffness (13.4%). Polyform™ had the highest failure load (53.8 N) while Ultrapro™ had the lowest (7.83 N). Novasilk™ (89.4%) and Ultrapro™ (87.9%) had the highest relative elongations at mesh failure while Ascend™ had the lowest (40.2%). Ascend™ had the least relative elongation after three protocols of cyclic loading (3.0%, 9.8%, and 9.7%). CONCLUSIONS: Current vaginal meshes demonstrate marked variation in biomechanical characteristics which may impact the in vivo behavior.
INTRODUCTION AND HYPOTHESIS: Recently, numerous type I macroporous polypropylene vaginal meshes have been introduced into the market with little known of their differences. METHODS: Seven vaginal meshes were obtained and loaded to failure (n = 5/type). Additional cyclic loading determined permanent deformation with submaximal loading. RESULTS: The load elongation curves demonstrated a bilinear response with lower stiffness (N/mm), followed by higher stiffness. Ascend™ was the stiffest mesh in both regions of the load elongation curve (0.72 and 1.66 N/mm) with the lowest transition to higher stiffness (13.4%). Polyform™ had the highest failure load (53.8 N) while Ultrapro™ had the lowest (7.83 N). Novasilk™ (89.4%) and Ultrapro™ (87.9%) had the highest relative elongations at mesh failure while Ascend™ had the lowest (40.2%). Ascend™ had the least relative elongation after three protocols of cyclic loading (3.0%, 9.8%, and 9.7%). CONCLUSIONS: Current vaginal meshes demonstrate marked variation in biomechanical characteristics which may impact the in vivo behavior.
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