Literature DB >> 22119613

Replication study of common variants in CDKAL1 and CDKN2A/2B genes associated with type 2 diabetes in Lebanese Arab population.

Rita Nemr1, Ahmad W Almawi, Akram Echtay, Mai S Sater, Hoda S Daher, Wassim Y Almawi.   

Abstract

We investigated the association of CDKAL1 (rs7754840 and rs7756992) and CDKN2A/2B (rs10811661) variants with T2DM. Higher MAF of rs7754840 and rs7756992 were seen in patients, and both were associated with T2DM under additive, dominant, and recessive models. CDKAL1 rs7754840 and rs7756992, but not CDKN2A/2B rs10811661, are associated with T2DM in Lebanese.
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

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Year:  2011        PMID： 22119613     DOI： 10.1016/j.diabres.2011.11.002

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN： 0168-8227            Impact factor:   5.602


  11 in total

1.  Association of rs7754840 G/C polymorphisms in CDKAL1 with type 2 diabetes: a meta-analysis of 70141 subjects.

Authors:  Muhadasi Tuerxunyiming; Patamu Mohemaiti; Hamulati Wufuer; Awaguli Tuheti
Journal:  Int J Clin Exp Med       Date:  2015-10-15

2.  The Uyghur population and genetic susceptibility to type 2 diabetes: potential role for variants in CDKAL1, JAZF1, and IGF1 genes.

Authors:  Manshu Song; Feifei Zhao; Longjin Ran; Mamatyusupu Dolikun; Lijuan Wu; Siqi Ge; Hao Dong; Qing Gao; Yanchun Zhai; Ling Zhang; Yuxiang Yan; Fen Liu; Xinghua Yang; Xiuhua Guo; Youxin Wang; Wei Wang
Journal:  OMICS       Date:  2015-03-18

3.  Association of gene variants with susceptibility to type 2 diabetes among Omanis.

Authors:  Sawsan Al-Sinani; Nicolas Woodhouse; Ali Al-Mamari; Omaima Al-Shafie; Mohammed Al-Shafaee; Said Al-Yahyaee; Mohammed Hassan; Deepali Jaju; Khamis Al-Hashmi; Mohammed Al-Abri; Khalid Al-Rassadi; Syed Rizvi; Yengo Loic; Philippe Froguel; Riad Bayoumi
Journal:  World J Diabetes       Date:  2015-03-15

Review 4.  Role of Ink4a/Arf locus in beta cell mass expansion under physiological and pathological conditions.

Authors:  Elisabet Salas; Nabil Rabhi; Philippe Froguel; Jean-Sébastien Annicotte
Journal:  J Diabetes Res       Date:  2014-02-06       Impact factor: 4.011

5.  Gene Polymorphism Association with Type 2 Diabetes and Related Gene-Gene and Gene-Environment Interactions in a Uyghur Population.

Authors:  Shan Xiao; Xiaoyun Zeng; Yong Fan; Yinxia Su; Qi Ma; Jun Zhu; Hua Yao
Journal:  Med Sci Monit       Date:  2016-02-13

6.  Different prevalence of T2DM risk alleles in Roma population in comparison with the majority Czech population.

Authors:  Jaroslav A Hubáček; Lenka Šedová; Věra Olišarová; Věra Adámková; Valérie Tóthová
Journal:  Mol Genet Genomic Med       Date:  2020-06-24       Impact factor: 2.183

7.  Association Between Single Nucleotide Polymorphisms in CDKAL1 and HHEX and Type 2 Diabetes in Chinese Population.

Authors:  Chuanyin Li; Keyu Shen; Man Yang; Ying Yang; Wenyu Tao; Siqi He; Li Shi; Yufeng Yao; Yiping Li
Journal:  Diabetes Metab Syndr Obes       Date:  2021-01-05       Impact factor: 3.168

8.  T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility.

Authors:  Michella Ghassibe-Sabbagh; Marc Haber; Angelique K Salloum; Yasser Al-Sarraj; Yasmine Akle; Kamal Hirbli; Jihane Romanos; Francis Mouzaya; Dominique Gauguier; Daniel E Platt; Hatem El-Shanti; Pierre A Zalloua
Journal:  Sci Rep       Date:  2014-12-08       Impact factor: 4.379

9.  Variants of CDKAL1 rs7754840 (G/C) and CDKN2A/2B rs10811661 (C/T) with gestational diabetes: insignificant association.

Authors:  Amr El Noury; Osama Azmy; Jehan Alsharnoubi; Sameh Salama; Ahmed Okasha; Weaam Gouda
Journal:  BMC Res Notes       Date:  2018-03-15

10.  Polymorphic genetic markers and how they are associated with clinical and metabolic indicators of type 2 diabetes mellitus in the Kazakh population.

Authors:  Valeriy V Benberin; Tamara A Vochshenkova; Gulshara Zh Abildinova; Anna V Borovikova; Almagul A Nagimtayeva
Journal:  J Diabetes Metab Disord       Date:  2021-01-20
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