Literature DB >> 22119531

Evidence-based recommendations for the use of negative pressure wound therapy in chronic wounds: steps towards an international consensus.

S Vig1, C Dowsett, L Berg, C Caravaggi, P Rome, H Birke-Sorensen, A Bruhin, M Chariker, M Depoorter, R Dunn, F Duteille, F Ferreira, J M Francos Martínez, G Grudzien, D Hudson, S Ichioka, R Ingemansson, S Jeffery, E Krug, C Lee, M Malmsjo, N Runkel, R Martin, J Smith.   

Abstract

AIM: Negative Pressure Wound Therapy (NPWT) has become widely adopted over the last 15 years and over 1000 peer-reviewed publications are available describing its use. Despite this, there remains uncertainty regarding several aspects of usage. In order to respond to this gap a global expert panel was convened to develop evidence-based recommendations describing the use of NPWT. In this communication the results of the study of evidence in chronic wounds including pressure ulcers, diabetic foot ulcers (DFU), venous leg ulcers (VLU), and ischaemic lower limb wounds are reported.
METHODS: Evidence-based recommendations were obtained by a systematic review of the literature, grading of evidence, drafting of the recommendations by a global expert panel followed by a formal consultative consensus development program in which 422 independent healthcare professionals were able to agree or disagree with the recommendations. The criteria for agreement were set at 80% agreement. Evidence and recommendations were graded according to the SIGN (Scottish Intercollegiate Guidelines Network) classification system.
RESULTS: The primary treatment goal of NPWT in most chronic wounds is to achieve wound closure (either by secondary intention or preparing the wound for surgical closure). Secondary goals commonly include: to reduce wound dimensions, and to improve the quality of the wound bed. Thirteen evidence based recommendations were developed in total to address these treatment goals; 4 for pressure ulcers, 4 for DFU, 3 for ischaemic lower limb wounds and 2 for VLU.
CONCLUSION: The present evidence base is strongest for the use of NPWT in non-ischaemic DFU and weakest in VLU. The development of evidence-based recommendations for NPWT with direct validation from a large group of practicing clinicians offers a broader basis for consensus than work by an expert panel alone.
Copyright © 2011. Published by Elsevier Ltd.

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Year:  2011        PMID: 22119531     DOI: 10.1016/j.jtv.2011.07.002

Source DB:  PubMed          Journal:  J Tissue Viability        ISSN: 0965-206X            Impact factor:   2.932


  20 in total

1.  Comparison of bacteria and fungus-binding mesh, foam and gauze as fillers in negative pressure wound therapy--pressure transduction, wound edge contraction, microvascular blood flow and fluid retention.

Authors:  Malin Malmsjö; Richard Ingemansson; Sandra Lindstedt; Lotta Gustafsson
Journal:  Int Wound J       Date:  2012-06-21       Impact factor: 3.315

Review 2.  Treatment of anticoagulated patients with negative pressure wound therapy.

Authors:  Sharon L Boxall; Keryln Carville; Gavin D Leslie; Shirley J Jansen
Journal:  Int Wound J       Date:  2017-03-15       Impact factor: 3.315

3.  A Multicenter Randomized Controlled Trial Comparing Treatment of Venous Leg Ulcers Using Mechanically Versus Electrically Powered Negative Pressure Wound Therapy.

Authors:  William A Marston; David G Armstrong; Alexander M Reyzelman; Robert S Kirsner
Journal:  Adv Wound Care (New Rochelle)       Date:  2015-02-01       Impact factor: 4.730

Review 4.  Updates in Diabetic Wound Healing, Inflammation, and Scarring.

Authors:  Nina Dasari; Austin Jiang; Anna Skochdopole; Jayer Chung; Edward M Reece; Joshua Vorstenbosch; Sebastian Winocour
Journal:  Semin Plast Surg       Date:  2021-07-15       Impact factor: 2.195

5.  Validation of a Manual Negative Pressure Wound Therapy Device (PragmaVAC) for Acute and Chronic Wounds: A Prospective, Randomized, Controlled Trial.

Authors:  Mahmoud Hariri; Bakry Maaz; Measser Netfagi; Jude Alawa; Ahmad Sattouf; Hussam Alden Dubies; Jehad Alahmad; Muhammet Fuat Seyitisa; Amandine Godier-Furnemont; Abedalkarem Ghali; Ahmad Ghandour; Zohair Abdullah; Munther Alsaleh; Ibrahim Almousa; Waiel Habib; Hisham Alshaer
Journal:  World J Surg       Date:  2022-09-29       Impact factor: 3.282

6.  Failure by congestion of pedicled and free flaps for reconstruction of lower limbs after trauma: the role of negative-pressure wound therapy.

Authors:  L Vaienti; R Gazzola; E Benanti; F Leone; A Marchesi; P C Parodi; M Riccio
Journal:  J Orthop Traumatol       Date:  2013-03-31

7.  Negative-pressure wound therapy for management of diabetic foot wounds: a review of the mechanism of action, clinical applications, and recent developments.

Authors:  Muhammed Y Hasan; Rachel Teo; Aziz Nather
Journal:  Diabet Foot Ankle       Date:  2015-07-01

Review 8.  Contemporary evaluation and management of the diabetic foot.

Authors:  Bauer E Sumpio
Journal:  Scientifica (Cairo)       Date:  2012-10-09

9.  Use of bacteria- and fungus-binding mesh in negative pressure wound therapy provides significant granulation tissue without tissue ingrowth.

Authors:  Malin Malmsjö; Sandra Lindstedt; Richard Ingemansson; Lotta Gustafsson
Journal:  Eplasty       Date:  2014-01-17

10.  Negative pressure wound therapy for managementof the surgical incision in orthopaedic surgery: A review of evidence and mechanisms for an emerging indication.

Authors:  S Karlakki; M Brem; S Giannini; V Khanduja; J Stannard; R Martin
Journal:  Bone Joint Res       Date:  2013-12-18       Impact factor: 5.853

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