Literature DB >> 22112370

Experimental characterization of lateral profiles of scanned proton and carbon ion pencil beams for improved beam models in ion therapy treatment planning.

J Schwaab1, S Brons, J Fieres, K Parodi.   

Abstract

Scanned ion pencil beams carry a low-dose envelope which can extend up to several centimeters from the individual beam central axis. Depending on the energy and species of the beam, this halo consists mainly of secondary particles produced by nuclear interactions in the target or of particles undergoing multiple Coulomb scattering in the beam line components. This halo is often neglected by single Gaussian beam modeling in current treatment planning systems. One possibility of improving the accuracy of treatment planning is to upgrade the used pencil beam models by adding a description of the low-dose envelope. But at the same time it is crucial to keep the calculation time and the complexity for treatment planning in reasonable limits. As a first approach we measured the lateral beam profiles of scanned proton and carbon ion pencil beams at different energies and depths in water and air at the Heidelberg Ion Beam Therapy Center. Then we tried to describe their beam halo by adding a supplementary Gaussian function to the standard single Gauss modeling which is used at the moment by our treatment planning systems. This analysis helped to identify trends in the parameters describing the lateral beam broadening to support its modeling. Finally, it is shown that the accuracy of treatment planning could be improved by the proposed upgrade of the pencil beam model. In particular, the presented experimental data can be either used directly as input for dose calculation or serve for representative comparison with the results of calculation models such as Monte Carlo simulations for the generation of lateral basic data to be input in upgraded beam models of treatment planning systems.

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Year:  2011        PMID: 22112370     DOI: 10.1088/0031-9155/56/24/009

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  12 in total

1.  Initial development of goCMC: a GPU-oriented fast cross-platform Monte Carlo engine for carbon ion therapy.

Authors:  Nan Qin; Marco Pinto; Zhen Tian; Georgios Dedes; Arnold Pompos; Steve B Jiang; Katia Parodi; Xun Jia
Journal:  Phys Med Biol       Date:  2017-01-31       Impact factor: 3.609

2.  Experimental and Monte Carlo characterization of a dynamic collimation system prototype for pencil beam scanning proton therapy.

Authors:  Blake R Smith; Mark Pankuch; Daniel E Hyer; Wesley S Culberson
Journal:  Med Phys       Date:  2020-09-09       Impact factor: 4.071

3.  A method for modeling laterally asymmetric proton beamlets resulting from collimation.

Authors:  Edgar Gelover; Dongxu Wang; Patrick M Hill; Ryan T Flynn; Mingcheng Gao; Steve Laub; Mark Pankuch; Daniel E Hyer
Journal:  Med Phys       Date:  2015-03       Impact factor: 4.071

4.  Clinical Commissioning of a Pencil Beam Scanning Treatment Planning System for Proton Therapy.

Authors:  Jatinder Saini; Ning Cao; Stephen R Bowen; Miguel Herrera; Daniel Nicewonger; Tony Wong; Charles D Bloch
Journal:  Int J Part Ther       Date:  2016-08-29

5.  The influence of beam delivery uncertainty on dose uniformity and penumbra for pencil beam scanning in carbon-ion radiotherapy.

Authors:  Yue Li; Yunzhe Gao; Xinguo Liu; Jian Shi; Jiawen Xia; Jiancheng Yang; Lijun Mao
Journal:  PLoS One       Date:  2021-04-01       Impact factor: 3.240

6.  Monte Carlo-based parametrization of the lateral dose spread for clinical treatment planning of scanned proton and carbon ion beams.

Authors:  Katia Parodi; Andrea Mairani; Florian Sommerer
Journal:  J Radiat Res       Date:  2013-07       Impact factor: 2.724

7.  The FLUKA Code: An Accurate Simulation Tool for Particle Therapy.

Authors:  Giuseppe Battistoni; Julia Bauer; Till T Boehlen; Francesco Cerutti; Mary P W Chin; Ricardo Dos Santos Augusto; Alfredo Ferrari; Pablo G Ortega; Wioletta Kozłowska; Giuseppe Magro; Andrea Mairani; Katia Parodi; Paola R Sala; Philippe Schoofs; Thomas Tessonnier; Vasilis Vlachoudis
Journal:  Front Oncol       Date:  2016-05-11       Impact factor: 6.244

8.  A simplified Monte Carlo algorithm considering large-angle scattering for fast and accurate calculation of proton dose.

Authors:  Taisuke Takayanagi; Shusuke Hirayama; Shinichiro Fujitaka; Rintaro Fujimoto
Journal:  J Appl Clin Med Phys       Date:  2017-11-27       Impact factor: 2.102

9.  Fast Pencil Beam Dose Calculation for Proton Therapy Using a Double-Gaussian Beam Model.

Authors:  Joakim da Silva; Richard Ansorge; Rajesh Jena
Journal:  Front Oncol       Date:  2015-12-18       Impact factor: 6.244

10.  Fast robust dose calculation on GPU for high-precision 1H, 4He, 12C and 16O ion therapy: the FRoG platform.

Authors:  Stewart Mein; Kyungdon Choi; Benedikt Kopp; Thomas Tessonnier; Julia Bauer; Alfredo Ferrari; Thomas Haberer; Jürgen Debus; Amir Abdollahi; Andrea Mairani
Journal:  Sci Rep       Date:  2018-10-04       Impact factor: 4.379

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