Literature DB >> 221108

Morphological and biochemical properties of a new human breast cancer cell line.

A J Langlois, W D Holder, J D Iglehart, W A Nelson-Rees, S A Wells, D P Bolognesi.   

Abstract

DU4475 is a new human breast cell line derived from a cutaneous metastatic nodule from a patient with advanced breast cancer. It has been in continuous culture for more than 1 year and has survived 140 subcultivations. The cells grow in suspension, displaying clusters and free-floating aggregates with serpentine-like outgrowths. The cell line is hypotetraploid with modal chromosome numbers between 86 and 93 and possesses five to six distinctive marker chromosomes. The cells grow readily in athymic nude mice and produce tumors from which cells can be reintroduced to culture in vitro.

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Year:  1979        PMID： 221108

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  18 in total

1.  Effect of selenium compounds and thiols on human mammary tumor cells.

Authors:  L Yan; J A Yee; L M Boylan; J E Spallholz
Journal:  Biol Trace Elem Res       Date:  1991-08       Impact factor: 3.738

2.  Investigations into the potential role of aberrant N-acetylgalactosamine glycans in tumour cell interactions with basement membrane components.

Authors:  Susan A Brooks; Debbie M S Hall
Journal:  Clin Exp Metastasis       Date:  2002       Impact factor: 5.150

3.  Description of a new human breast cancer cell line, IIB-BR-G, established from a primary undifferentiated tumor.

Authors:  L Bover; M Barrio; I Slavutsky; A I Bravo; C Quintans; A Bagnăti; B Lema; J Schiaffi; R Yomha; J Mordoh
Journal:  Breast Cancer Res Treat       Date:  1991-09       Impact factor: 4.872

4.  Cultured cell lines from human breast cancer biopsies and xenografts.

Authors:  W M Lewko; R Vaghmar; D Hubbard; M Moore; Y J He; L Chang; S Husseini; K Wallwork; G B Thurman; R K Oldham
Journal:  Breast Cancer Res Treat       Date:  1990-12       Impact factor: 4.872

Review 5.  Stem cells and the development of mammary cancers in experimental rats and in humans.

Authors:  P S Rudland
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

6.  5'-AMP-activated protein kinase (AMPK) supports the growth of aggressive experimental human breast cancer tumors.

Authors:  Keith R Laderoute; Joy M Calaoagan; Wan-Ru Chao; Dominc Dinh; Nicholas Denko; Sarah Duellman; Jessica Kalra; Xiaohe Liu; Ioanna Papandreou; Lidia Sambucetti; Laszlo G Boros
Journal:  J Biol Chem       Date:  2014-07-03       Impact factor: 5.157

7.  Quantitation of human mammary epithelial antigens in cells cultured from normal and cancerous breast tissues.

Authors:  M Sasaki; J A Peterson; R L Ceriani
Journal:  In Vitro       Date:  1981-02

8.  Immunization of breast cancer patients using a synthetic sialyl-Tn glycoconjugate plus Detox adjuvant.

Authors:  G D MacLean; M Reddish; R R Koganty; T Wong; S Gandhi; M Smolenski; J Samuel; J M Nabholtz; B M Longenecker
Journal:  Cancer Immunol Immunother       Date:  1993       Impact factor: 6.968

9.  Large duplications at reciprocal translocation breakpoints that might be the counterpart of large deletions and could arise from stalled replication bubbles.

Authors:  Karen D Howarth; Jessica C M Pole; Juliet C Beavis; Elizabeth M Batty; Scott Newman; Graham R Bignell; Paul A W Edwards
Journal:  Genome Res       Date:  2011-01-20       Impact factor: 9.043

10.  Establishment and Characterization of a HER2-Positive Cell Line Derived From the Pleural Effusion of a Drug-Resistant Breast Cancer Patient.

Authors:  Zhaoqing Li; Wenying Zhuo; Lini Chen; Xun Zhang; Cong Chen; Dengdi Hu; Yongxia Chen; Jingjing Yang; Yulu Zhou; Misha Mao; Ling Xu; Siwei Ju; Jun Shen; Qinchuan Wang; Minjun Dong; Shuduo Xie; Jichun Zhou; Linbo Wang
Journal:  Front Cell Dev Biol       Date:  2021-06-01
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