Literature DB >> 22110006

Sticky nanoparticles: a platform for siRNA delivery by a bis(zinc(II) dipicolylamine)-functionalized, self-assembled nanoconjugate.

Gang Liu1, Ki Young Choi, Ashwinkumar Bhirde, Magdalena Swierczewska, Juan Yin, Sang Wook Lee, Jae Hyung Park, Jong In Hong, Jin Xie, Gang Niu, Dale O Kiesewetter, Seulki Lee, Xiaoyuan Chen.   

Abstract

Delivering the goods: Multifunctional, self-assembled, polymeric nanoparticles for the simultaneous delivery of small-molecule drugs and siRNA have been synthesized. The nanoparticles are composed of biodegradable hyaluronic acid, for tumor targeting and cellular delivery, and a high siRNA binding affinity is provided by a Zn(II)-dipicolylamine analogue as an artificial phosphate-binding receptor (see scheme).
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Year:  2011        PMID： 22110006      PMCID： PMC3622591          DOI： 10.1002/anie.201105565

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  20 in total

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Authors:  Gang Liu; Magdalena Swierczewska; Seulki Lee; Xiaoyuan Chen
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Review 3.  Hyaluronidases: their genomics, structures, and mechanisms of action.

Authors:  Robert Stern; Mark J Jedrzejas
Journal:  Chem Rev       Date:  2006-03       Impact factor: 60.622

Review 4.  Bio-inspired, bioengineered and biomimetic drug delivery carriers.

Authors:  Jin-Wook Yoo; Darrell J Irvine; Dennis E Discher; Samir Mitragotri
Journal:  Nat Rev Drug Discov       Date:  2011-07-01       Impact factor: 84.694

5.  Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells.

Authors:  S M Elbashir; J Harborth; W Lendeckel; A Yalcin; K Weber; T Tuschl
Journal:  Nature       Date:  2001-05-24       Impact factor: 49.962

6.  PEGylation of hyaluronic acid nanoparticles improves tumor targetability in vivo.

Authors:  Ki Young Choi; Kyung Hyun Min; Hong Yeol Yoon; Kwangmeyung Kim; Jae Hyung Park; Ick Chan Kwon; Kuiwon Choi; Seo Young Jeong
Journal:  Biomaterials       Date:  2010-12-14       Impact factor: 12.479

7.  Dinuclear metal(II) complexes of polybenzimidazole ligands as carriers for DNA delivery.

Authors:  Liang Liu; Hang Zhang; Xianggao Meng; Jun Yin; Dongfeng Li; Changlin Liu
Journal:  Biomaterials       Date:  2009-11-11       Impact factor: 12.479

8.  Self-assembled hyaluronic acid nanoparticles for active tumor targeting.

Authors:  Ki Young Choi; Hyunjin Chung; Kyung Hyun Min; Hong Yeol Yoon; Kwangmeyung Kim; Jae Hyung Park; Ick Chan Kwon; Seo Young Jeong
Journal:  Biomaterials       Date:  2009-09-26       Impact factor: 12.479

Review 9.  Lipid-based systemic delivery of siRNA.

Authors:  Yu-Cheng Tseng; Subho Mozumdar; Leaf Huang
Journal:  Adv Drug Deliv Rev       Date:  2009-03-26       Impact factor: 15.470

Review 10.  Interfering with disease: a progress report on siRNA-based therapeutics.

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  27 in total

1.  Zn(II)-dipicolylamine-based metallo-lipids as novel non-viral gene vectors.

Authors:  Rong-Chuan Su; Qiang Liu; Wen-Jing Yi; Zhi-Gang Zhao
Journal:  J Biol Inorg Chem       Date:  2017-05-16       Impact factor: 3.358

Review 2.  Rigid nanoparticle-based delivery of anti-cancer siRNA: challenges and opportunities.

Authors:  Zhiyong Wang; Gang Liu; Hairong Zheng; Xiaoyuan Chen
Journal:  Biotechnol Adv       Date:  2013-09-05       Impact factor: 14.227

3.  Targeted delivery of siRNA-generating DNA nanocassettes using multifunctional nanoparticles.

Authors:  Young-Seok Cho; Gee Young Lee; Hari Krishna Sajja; Weiping Qian; Zehong Cao; Weiling He; Prasanthi Karna; Xiaoyuan Chen; Hui Mao; Y Andrew Wang; Lily Yang
Journal:  Small       Date:  2013-01-06       Impact factor: 13.281

4.  Gadolinium embedded iron oxide nanoclusters as T1-T2 dual-modal MRI-visible vectors for safe and efficient siRNA delivery.

Authors:  Xiaoyong Wang; Zijian Zhou; Zhiyong Wang; Yunxin Xue; Yun Zeng; Jinhao Gao; Lei Zhu; Xianzhong Zhang; Gang Liu; Xiaoyuan Chen
Journal:  Nanoscale       Date:  2013-09-07       Impact factor: 7.790

5.  Theranostic nanoparticles based on PEGylated hyaluronic acid for the diagnosis, therapy and monitoring of colon cancer.

Authors:  Ki Young Choi; Eun Jung Jeon; Hong Yeol Yoon; Beom Suk Lee; Jin Hee Na; Kyung Hyun Min; Sang Yoon Kim; Seung-Jae Myung; Seulki Lee; Xiaoyuan Chen; Ick Chan Kwon; Kuiwon Choi; Seo Young Jeong; Kwangmeyung Kim; Jae Hyung Park
Journal:  Biomaterials       Date:  2012-06-09       Impact factor: 12.479

Review 6.  Cancer-Associated, Stimuli-Driven, Turn on Theranostics for Multimodality Imaging and Therapy.

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Journal:  Adv Mater       Date:  2017-03-29       Impact factor: 30.849

7.  Convenient Synthesis of Multivalent Zinc(II)-Dipicolylamine Complexes for Molecular Recognition.

Authors:  Shuzhang Xiao; Serhan Turkyilmaz; Bradley D Smith
Journal:  Tetrahedron Lett       Date:  2013-02-20       Impact factor: 2.415

8.  A nanoparticle formula for delivering siRNA or miRNAs to tumor cells in cell culture and in vivo.

Authors:  Ki Young Choi; Oscar F Silvestre; Xinglu Huang; Naoki Hida; Gang Liu; Don N Ho; Seulki Lee; Sang Wook Lee; Jong In Hong; Xiaoyuan Chen
Journal:  Nat Protoc       Date:  2014-07-17       Impact factor: 13.491

9.  Effect of Bridging Anions on the Structure and Stability of Phenoxide Bridged Zinc Dipicolylamine Coordination Complexes.

Authors:  Edward J O'Neil; Hua Jiang; Bradley D Smith
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Review 10.  Imaging-guided delivery of RNAi for anticancer treatment.

Authors:  Junqing Wang; Peng Mi; Gan Lin; Yì Xiáng J Wáng; Gang Liu; Xiaoyuan Chen
Journal:  Adv Drug Deliv Rev       Date:  2016-01-22       Impact factor: 15.470
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