PURPOSE: To evaluate the possible side effects and potential protection 5 years after implantation of an intraocular lens (IOL) with a blue-light filter (yellow tinted). SETTING: Ophthalmology Department, University of São Paulo, São Paulo, Brazil. DESIGN: Prospective randomized clinical study. METHODS:Patients with bilateral visually significant cataract randomly received anultraviolet (UV) and blue light-filtering IOL (Acrysof Natural SN60AT) in 1 eye and an acrylic UV light-filtering only IOL (Acrysof SA60AT) in the fellow eye. The primary outcome measures were contrast sensitivity, color vision, and macular findings 5 years after surgery. RESULTS: The study enrolled 60 eyes of 30 patients. There were no significant clinical or optical coherence tomography findings in terms of age-related macular degeneration in any eye. There were no statistically significant differences in central macular thickness between the 2 IOL groups (P=.712). There were also no significant between-group differences under photopic or scotopic conditions at any spatial frequency studied. No statistically significant differences in the color discrimination test were found between the 2 IOL groups (P=.674). CONCLUSIONS: After 5 years, there were no significant differences in color perception, scotopic contrast sensitivity, or photopic contrast sensitivity between the blue light-filtering (yellow-tinted) IOL and the IOL with a UV-light filter only (untinted). The potential advantage of the tinted IOL in providing protection to macular cells remains unclear.
RCT Entities:
PURPOSE: To evaluate the possible side effects and potential protection 5 years after implantation of an intraocular lens (IOL) with a blue-light filter (yellow tinted). SETTING: Ophthalmology Department, University of São Paulo, São Paulo, Brazil. DESIGN: Prospective randomized clinical study. METHODS:Patients with bilateral visually significant cataract randomly received an ultraviolet (UV) and blue light-filtering IOL (Acrysof Natural SN60AT) in 1 eye and an acrylic UV light-filtering only IOL (Acrysof SA60AT) in the fellow eye. The primary outcome measures were contrast sensitivity, color vision, and macular findings 5 years after surgery. RESULTS: The study enrolled 60 eyes of 30 patients. There were no significant clinical or optical coherence tomography findings in terms of age-related macular degeneration in any eye. There were no statistically significant differences in central macular thickness between the 2 IOL groups (P=.712). There were also no significant between-group differences under photopic or scotopic conditions at any spatial frequency studied. No statistically significant differences in the color discrimination test were found between the 2 IOL groups (P=.674). CONCLUSIONS: After 5 years, there were no significant differences in color perception, scotopic contrast sensitivity, or photopic contrast sensitivity between the blue light-filtering (yellow-tinted) IOL and the IOL with a UV-light filter only (untinted). The potential advantage of the tinted IOL in providing protection to macular cells remains unclear.
Authors: Peter Mojzis; Zdenek Bombera; Sarka Vesela; Daniela Klapuchova; Peter Ziak; David P Piñero Journal: Int J Ophthalmol Date: 2016-01-18 Impact factor: 1.779
Authors: Marcella Spoor; Behdokht Hosseini; Bart van Alphen; Maarten A Frens; Jos N van der Geest Journal: J Ophthalmol Date: 2014-04-06 Impact factor: 1.909
Authors: M Amparo DIez-Ajenjo; M Carmen GarcIa-Domene; Cristina Peris-MartInez; Jos M Artigas; Adelina Felipe Journal: Indian J Ophthalmol Date: 2014-11 Impact factor: 1.848