| Literature DB >> 22101779 |
B Bauer1, M Majic, S Rauthe, E-B Bröcker, A Kerstan.
Abstract
We report the case of a long-lasting cutaneous side effect after inappropriate use of Octenisept® solution (containing octenidine and phenoxyethanol). Following lavage of an abscess in the inguinal region, a painful erythematous induration mimicking cellulitis persisted for several months. Manual lymphatic drainage considerably improved the symptoms. Octenisept® shows considerable tissue toxicity in vivo including - but not restricted to - blood vessel damage. Deterioration of endothelial cells followed by oedema and continued tissue damage can be seen histologically. Despite the fact that there is a circular letter issued by the manufacturer as well as a boxed warning on the bottles, the awareness to avoid this misuse of Octenisept® is still lacking.Entities:
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Year: 2012 PMID: 22101779 DOI: 10.1007/s00113-011-2116-5
Source DB: PubMed Journal: Unfallchirurg ISSN: 0177-5537 Impact factor: 1.000