Literature DB >> 22101779

[Persistent swelling after flushing of an abscess with Octenisept®].

B Bauer1, M Majic, S Rauthe, E-B Bröcker, A Kerstan.   

Abstract

We report the case of a long-lasting cutaneous side effect after inappropriate use of Octenisept® solution (containing octenidine and phenoxyethanol). Following lavage of an abscess in the inguinal region, a painful erythematous induration mimicking cellulitis persisted for several months. Manual lymphatic drainage considerably improved the symptoms. Octenisept® shows considerable tissue toxicity in vivo including - but not restricted to - blood vessel damage. Deterioration of endothelial cells followed by oedema and continued tissue damage can be seen histologically. Despite the fact that there is a circular letter issued by the manufacturer as well as a boxed warning on the bottles, the awareness to avoid this misuse of Octenisept® is still lacking.

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Year:  2012        PMID: 22101779     DOI: 10.1007/s00113-011-2116-5

Source DB:  PubMed          Journal:  Unfallchirurg        ISSN: 0177-5537            Impact factor:   1.000


  7 in total

1.  [Wound closure after irrigation with Octenisept® without possibility for drainage].

Authors:  A M Högele; J Neu
Journal:  Unfallchirurg       Date:  2011-01       Impact factor: 1.000

2.  Influence of the antiseptic agents polyhexanide and octenidine on FL cells and on healing of experimental superficial aseptic wounds in piglets. A double-blind, randomised, stratified, controlled, parallel-group study.

Authors:  A Kramer; B Roth; G Müller; P Rudolph; N Klöcker
Journal:  Skin Pharmacol Physiol       Date:  2004 May-Jun       Impact factor: 3.479

3.  Persistent subcutaneous oedema and aseptic fatty tissue necrosis after using octenisept.

Authors:  C J Schupp; S Holland-Cunz
Journal:  Eur J Pediatr Surg       Date:  2009-06-04       Impact factor: 2.191

4.  [Tissue toxicity of antiseptics].

Authors:  T Kalteis; C Lüring; J Schaumburger; L Perlick; H Bäthis; J Grifka
Journal:  Z Orthop Ihre Grenzgeb       Date:  2003 Mar-Apr

5.  [A comparative in vitro study of cell toxicity of clinically used antiseptics].

Authors:  T Hirsch; F Jacobsen; A Rittig; O Goertz; A Niederbichler; H U Steinau; H M Seipp; L Steinstraesser
Journal:  Hautarzt       Date:  2009-12       Impact factor: 0.751

6.  [Severe side effects after Octenisept irrigation of penetrating wounds in children].

Authors:  W Hülsemann; R Habenicht
Journal:  Handchir Mikrochir Plast Chir       Date:  2009-09-29       Impact factor: 1.018

7.  The impact of topical antiseptics on skin microcirculation.

Authors:  S Langer; M Sedigh Salakdeh; O Goertz; H U Steinau; L Steinstraesser; H H Homann
Journal:  Eur J Med Res       Date:  2004-09-29       Impact factor: 2.175

  7 in total
  1 in total

1.  [Persistent reddening and induration after wound cleansing with octenidine].

Authors:  M Seegräber; A Wollenberg
Journal:  Hautarzt       Date:  2017-04       Impact factor: 0.751

  1 in total

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