Literature DB >> 22099144

The disease burden of childhood adversities in adults: a population-based study.

Pim Cuijpers1, Filip Smit, Froukje Unger, Yvonne Stikkelbroek, Margreet Ten Have, Ron de Graaf.   

Abstract

OBJECTIVES: There is much evidence showing that childhood adversities have considerable effects on the mental and physical health of adults. It could be assumed therefore, that the disease burden of childhood adversities is high. It has not yet been examined, however, whether this is true.
METHOD: We used data of a large representative sample (N=7,076) of the general population in the Netherlands. We calculated the disability weight (DW) for each respondent. The DW is a weight factor that reflects the severity of a disease or condition on a scale from 0 (perfect health) to 1 (equivalent to death). We used an algorithm based on the SF-6D to estimate DW. Because the DW indicates the proportion of a healthy life year that is reduced by the specific health state of the individual, it also possible to calculate the total number of years lost due to disability (YLD) in the population. We calculated the years lived with disability (YLD) for 9 different childhood adversities (in the areas of parental psychopathology; abuse and neglect; major life events), as well as for major categories of mental disorders and general medical disorders.
RESULTS: All 9 adversities resulted in a significantly increased DW, except death of a parent before the age of 16. Adversities in the category of abuse and neglect are associated with the highest DWs (0.057), followed by parental psychopathology (0.031) and life events during childhood (0.012). All adversities (46.4% of the population reports one or more adversity) are associated with 20.7 YLD/1,000, which is more than all mental disorders together (12.9 YLD/1,000). The category of abuse/neglect has the highest YLD/1,000 (15.8), which is also higher than all mental disorders together. Adjustment for the presence of mental and general medical disorders resulted in comparable outcomes.
CONCLUSIONS: Childhood adversities are more important from a public health point of view than all common mental disorders together, and should be a priority for public health interventions.
Copyright © 2011 Elsevier Ltd. All rights reserved.

Entities:  

Mesh:

Year:  2011        PMID: 22099144     DOI: 10.1016/j.chiabu.2011.06.005

Source DB:  PubMed          Journal:  Child Abuse Negl        ISSN: 0145-2134


  40 in total

1.  Sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume.

Authors:  Daphne Everaerd; Lotte Gerritsen; Mark Rijpkema; Thomas Frodl; Iris van Oostrom; Barbara Franke; Guillén Fernández; Indira Tendolkar
Journal:  Neuropsychopharmacology       Date:  2012-03-21       Impact factor: 7.853

2.  History of childhood adversity is positively associated with ventral striatal dopamine responses to amphetamine.

Authors:  Lynn M Oswald; Gary S Wand; Hiroto Kuwabara; Dean F Wong; Shijun Zhu; James R Brasic
Journal:  Psychopharmacology (Berl)       Date:  2014-01-22       Impact factor: 4.530

3.  Physical neglect during childhood alters white matter connectivity in healthy young males.

Authors:  Indira Tendolkar; Johan Mårtensson; Simone Kühn; Floris Klumpers; Guillén Fernández
Journal:  Hum Brain Mapp       Date:  2017-12-17       Impact factor: 5.038

4.  Long-term economic consequences of child maltreatment: a population-based study.

Authors:  Frederick W Thielen; Margreet Ten Have; Ron de Graaf; Pim Cuijpers; Aartjan Beekman; Silvia Evers; Filip Smit
Journal:  Eur Child Adolesc Psychiatry       Date:  2016-05-06       Impact factor: 4.785

5.  Adverse childhood experiences and disability in U.S. adults.

Authors:  Sophia Miryam Schüssler-Fiorenza Rose; Dawei Xie; Margaret Stineman
Journal:  PM R       Date:  2014-01-28       Impact factor: 2.298

6.  Associations between childhood adversity, adult stressful life events, and past-year drug use disorders in the National Epidemiological Study of Alcohol and Related Conditions (NESARC).

Authors:  Bronwyn Myers; Katie A McLaughlin; Shuai Wang; Carlos Blanco; Dan J Stein
Journal:  Psychol Addict Behav       Date:  2014-08-18

7.  Life-course impact of child maltreatment on midlife health-related quality of life in women: longitudinal mediation analysis for potential pathways.

Authors:  Hsing-Hua S Lin; Ashley I Naimi; Maria M Brooks; Gale A Richardson; Jessica G Burke; Joyce T Bromberger
Journal:  Ann Epidemiol       Date:  2020-01-18       Impact factor: 3.797

8.  Child maltreatment as a social determinant of midlife health-related quality of life in women: do psychosocial factors explain this association?

Authors:  Hsing-Hua S Lin; Ashley I Naimi; Maria M Brooks; Gale A Richardson; Jessica G Burke; Joyce T Bromberger
Journal:  Qual Life Res       Date:  2018-08-18       Impact factor: 4.147

9.  Childhood abuse and deprivation are associated with distinct sex-dependent differences in brain morphology.

Authors:  Daphne Everaerd; Floris Klumpers; Marcel Zwiers; Tulio Guadalupe; Barbara Franke; Iris van Oostrom; Aart Schene; Guillén Fernández; Indira Tendolkar
Journal:  Neuropsychopharmacology       Date:  2015-11-18       Impact factor: 7.853

Review 10.  Quality of life in maltreated children and adult survivors of child maltreatment: a systematic review.

Authors:  S Weber; A Jud; M A Landolt
Journal:  Qual Life Res       Date:  2015-08-06       Impact factor: 4.147

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