Literature DB >> 22095772

Immunosuppressive small molecule discovered by structure-based virtual screening for inhibitors of protein-protein interactions.

Tim Geppert1, Stefanie Bauer, Jan A Hiss, Elea Conrad, Michael Reutlinger, Petra Schneider, Martin Weisel, Bernhard Pfeiffer, Karl-Heinz Altmann, Zoe Waibler, Gisbert Schneider.   

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Year:  2011        PMID： 22095772     DOI： 10.1002/anie.201105901

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  9 in total

1.  Small-molecule inhibitors of the interaction between the E3 ligase VHL and HIF1α.

Authors:  Dennis L Buckley; Jeffrey L Gustafson; Inge Van Molle; Anke G Roth; Hyun Seop Tae; Peter C Gareiss; William L Jorgensen; Alessio Ciulli; Craig M Crews
Journal:  Angew Chem Int Ed Engl       Date:  2012-10-12       Impact factor: 15.336

2.  Microvesicles in active lupus nephritis show Toll-like receptor 9-dependent co-expression of galectin-3 binding protein and double-stranded DNA.

Authors:  C H Nielsen; S Jacobsen; N S Rasmussen; C T Nielsen
Journal:  Clin Exp Immunol       Date:  2021-01-25       Impact factor: 5.732

3.  Stimulation of Mononuclear Cells Through Toll-Like Receptor 9 Induces Release of Microvesicles Expressing Double-Stranded DNA and Galectin 3-Binding Protein in an Interferon-α-Dependent Manner.

Authors:  Niclas Stefan Rasmussen; Christoffer Tandrup Nielsen; Søren Jacobsen; Claus Henrik Nielsen
Journal:  Front Immunol       Date:  2019-10-11       Impact factor: 7.561

4.  Docking-based identification of small-molecule binding sites at protein-protein interfaces.

Authors:  Mireia Rosell; Juan Fernández-Recio
Journal:  Comput Struct Biotechnol J       Date:  2020-11-21       Impact factor: 7.271

5.  Host MOV10 is induced to restrict herpes simplex virus 1 lytic infection by promoting type I interferon response.

Authors:  Xiyuan Yang; Ze Xiang; Zeyu Sun; Feiyang Ji; Keyi Ren; Dongli Pan
Journal:  PLoS Pathog       Date:  2022-02-14       Impact factor: 6.823

6.  17β-Oestradiol Protects from Hepatitis C Virus Infection through Induction of Type I Interferon.

Authors:  Matteo Nazzareno Barbaglia; James Michael Harris; Artem Smirnov; Michela Emma Burlone; Cristina Rigamonti; Mario Pirisi; Rosalba Minisini; Andrea Magri
Journal:  Viruses       Date:  2022-08-18       Impact factor: 5.818

Review 7.  Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.

Authors:  Luca Laraia; Grahame McKenzie; David R Spring; Ashok R Venkitaraman; David J Huggins
Journal:  Chem Biol       Date:  2015-06-18

Review 8.  Evolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery.

Authors:  Stephani Joy Y Macalino; Shaherin Basith; Nina Abigail B Clavio; Hyerim Chang; Soosung Kang; Sun Choi
Journal:  Molecules       Date:  2018-08-06       Impact factor: 4.411

Review 9.  Hierarchical virtual screening approaches in small molecule drug discovery.

Authors:  Ashutosh Kumar; Kam Y J Zhang
Journal:  Methods       Date:  2014-07-27       Impact factor: 3.608
  9 in total

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