| Literature DB >> 22094251 |
Marc R Mansour1, A Thomas Look.
Abstract
In a recent paper in Cell, Oricchio et al. identify EPHA7 as a tumor suppressor gene residing in the 6q-deleted region in follicular lymphoma. A truncated EPHA7(TR) isoform is secreted by normal B cells, inhibits EPHA2 signaling, and, as a secreted tumor suppressor protein, has potential as a targeted therapeutic polypeptide. 2011 Elsevier Inc. All rights reserved.Entities:
Year: 2011 PMID： 22094251 DOI： 10.1016/j.ccr.2011.10.027
Source DB: PubMed Journal: Cancer Cell ISSN： 1535-6108 Impact factor: 31.743