BACKGROUND: Mortality of patients with ST-segment elevation myocardial infarction (STEMI) with cardiogenic shock (CS) on admission remains high despite invasive treatment. The aim of this analysis was to assess the relationship between the infarct-related artery (IRA) and the early and 12-month outcomes of patients with STEMI and CS treated by percutaneous coronary intervention (PCI). METHODS: Two thousand ninety patients with STEMI and CS registered in the prospective Polish Registry of Acute Coronary Syndromes from October 2003 to November 2009 were included. RESULTS: The in-hospital mortality in the left main (LM), left anterior descending artery (LAD), circumflex artery (Cx), and right coronary artery (RCA) groups was 64.7%, 41.0%, 36.0%, and 30.8%, respectively, with p<0.0001. The 12-month mortality in the LM, LAD, Cx, and RCA groups was 77.7%, 58.2%, 55.1%, and 45.0%, respectively, with p<0.0001. After multivariate adjustment, LM as the IRA was significantly associated with higher 12-month mortality (hazard ratio=1.71, 95% confidence interval=1.28-2.27, p=0.0002). CONCLUSIONS: In-hospital and long-term mortality of patients with STEMI and CS treated by PCI are significantly correlated to the IRA, being highest for LM and lowest for RCA.
BACKGROUND: Mortality of patients with ST-segment elevation myocardial infarction (STEMI) with cardiogenic shock (CS) on admission remains high despite invasive treatment. The aim of this analysis was to assess the relationship between the infarct-related artery (IRA) and the early and 12-month outcomes of patients with STEMI and CS treated by percutaneous coronary intervention (PCI). METHODS: Two thousand ninety patients with STEMI and CS registered in the prospective Polish Registry of Acute Coronary Syndromes from October 2003 to November 2009 were included. RESULTS: The in-hospital mortality in the left main (LM), left anterior descending artery (LAD), circumflex artery (Cx), and right coronary artery (RCA) groups was 64.7%, 41.0%, 36.0%, and 30.8%, respectively, with p<0.0001. The 12-month mortality in the LM, LAD, Cx, and RCA groups was 77.7%, 58.2%, 55.1%, and 45.0%, respectively, with p<0.0001. After multivariate adjustment, LM as the IRA was significantly associated with higher 12-month mortality (hazard ratio=1.71, 95% confidence interval=1.28-2.27, p=0.0002). CONCLUSIONS: In-hospital and long-term mortality of patients with STEMI and CS treated by PCI are significantly correlated to the IRA, being highest for LM and lowest for RCA.
Authors: Tuija Javanainen; Heli Tolppanen; Johan Lassus; Markku S Nieminen; Alessandro Sionis; Jindrich Spinar; José Silva-Cardoso; Matias Greve Lindholm; Marek Banaszewski; Veli-Pekka Harjola; Raija Jurkko Journal: Ann Noninvasive Electrocardiol Date: 2018-05-30 Impact factor: 1.468
Authors: Georg Fuernau; Karl Fengler; Steffen Desch; Ingo Eitel; Franz-Josef Neumann; Hans-Georg Olbrich; Antoinette de Waha; Suzanne de Waha; Gert Richardt; Marcus Hennersdorf; Klaus Empen; Rainer Hambrecht; Christian Jung; Michael Böhm; Janine Pöss; Ruth H Strasser; Steffen Schneider; Taoufik Ouarrak; Gerhard Schuler; Karl Werdan; Uwe Zeymer; Holger Thiele Journal: Clin Res Cardiol Date: 2016-07-04 Impact factor: 5.460
Authors: Mariusz Gąsior; Piotr Desperak; Dariusz Dudek; Adam Witkowski; Paweł E Buszman; Przemysław Trzeciak; Michał Hawranek; Marek Gierlotka; Stanisław Bartuś; Marek Grygier; Michał Zembala; Janina Stępińska; Jacek Legutko; Wojciech Wojakowski Journal: J Clin Med Date: 2021-04-22 Impact factor: 4.241
Authors: Tuija Sabell; Marek Banaszewski; Johan Lassus; Markku S Nieminen; Heli Tolppanen; Toni Jäntti; Anu Kataja; Mari Hongisto; Lars Køber; Alessandro Sionis; John Parissis; Tuukka Tarvasmäki; Veli-Pekka Harjola; Raija Jurkko Journal: ESC Heart Fail Date: 2020-03-12