Literature DB >> 22087826

Flavonoids as acetylcholinesterase inhibitors.

I Uriarte-Pueyo1, M I Calvo.   

Abstract

Flavonoids are new promising potential natural compounds for treating Alzheimer's disease (AD). Actually most promising drugs for symptomatic treatment of AD are acetylcholinesterase inhibitors (AChEI). Flavonoids with AChE inhibitory activity and due to their well known antioxidant activity could be new multipotent drugs for AD treatment. This work focuses on natural and synthetic flavonoids inhibitors of the enzyme acetylcholinesterase (AChE). Over, all this review refers to 128 flavonoids, which are classified in chemical structure, and summarizes 64 references.

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Year:  2011        PMID： 22087826     DOI： 10.2174/092986711798184325

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN： 0929-8673            Impact factor:   4.530


  25 in total

1.  Synthesis of Quercetin-Metal Complexes, In Vitro and In Silico Anticholinesterase and Antioxidant Evaluation, and In Vivo Toxicological and Anxiolitic Activities.

Authors:  Wildson Max Barbosa da Silva; Solange de Oliveira Pinheiro; Daniela Ribeiro Alves; Jane Eire Silva Alencar de Menezes; Francisco Ernani Alves Magalhães; Francisca Crislândia Oliveira Silva; Jacilene Silva; Emmanuel Silva Marinho; Selene Maia de Morais
Journal:  Neurotox Res       Date:  2019-12-18       Impact factor: 3.911

2.  Multidimensional chemobehavior analysis of flavonoids and neuroactive compounds in zebrafish.

Authors:  Sean M Bugel; Robert L Tanguay
Journal:  Toxicol Appl Pharmacol       Date:  2018-02-27       Impact factor: 4.219

3.  Inhibitory Effects of Cannabinoids on Acetylcholinesterase and Butyrylcholinesterase Enzyme Activities.

Authors:  Tess Puopolo; Chang Liu; Hang Ma; Navindra P Seeram
Journal:  Med Cannabis Cannabinoids       Date:  2022-04-19

4.  Blood-Brain Barrier Permeability Study of Potential Neuroprotective Compounds Recovered From Plants and Agri-Food by-Products.

Authors:  José David Sánchez-Martínez; Alberto Valdés; Rocio Gallego; Zully Jimena Suárez-Montenegro; Marina Alarcón; Elena Ibañez; Gerardo Alvarez-Rivera; Alejandro Cifuentes
Journal:  Front Nutr       Date:  2022-06-16

5.  Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ.

Authors:  Dohyun Lee; Dong Gon Cha; Kyung Won Jo; Eunji Oh; Yoon Ha Choi; Somi Kim; Eun Seo Park; Jong Kyoung Kim; Kyong-Tai Kim
Journal:  Alzheimers Res Ther       Date:  2022-10-21       Impact factor: 8.823

6.  Rubus coreanus Miquel inhibits acetylcholinesterase activity and prevents cognitive impairment in a mouse model of dementia.

Authors:  Cho Rong Kim; Soo Jung Choi; Seung Sang Oh; Yoon Kyung Kwon; Na Young Lee; Gwi Gun Park; Youn-Jung Kim; Ho Jin Heo; Woo Jin Jun; Cheung-Seog Park; Dong-Hoon Shin
Journal:  J Med Food       Date:  2013-09       Impact factor: 2.786

7.  The Antiviral Drug Tilorone Is a Potent and Selective Inhibitor of Acetylcholinesterase.

Authors:  Patricia A Vignaux; Eni Minerali; Thomas R Lane; Daniel H Foil; Peter B Madrid; Ana C Puhl; Sean Ekins
Journal:  Chem Res Toxicol       Date:  2021-01-05       Impact factor: 3.739

8.  Various In Vitro Bioactivities of Secondary Metabolites Isolated from the Sponge Hyrtios aff. Erectus from the Red Sea Coast of Egypt.

Authors:  Asmaa Nabil-Adam; Mohamed A Shreadah; Nehad M Abd El Moneam; Samy A El-Assar
Journal:  Turk J Pharm Sci       Date:  2020-04-24

9.  Effects of a Proprietary Standardized Orthosiphon stamineus Ethanolic Leaf Extract on Enhancing Memory in Sprague Dawley Rats Possibly via Blockade of Adenosine A 2A Receptors.

Authors:  Annie George; Sasikala Chinnappan; Yogendra Choudhary; Vandana Kotak Choudhary; Praveen Bommu; Hoi Jin Wong
Journal:  Evid Based Complement Alternat Med       Date:  2015-11-08       Impact factor: 2.629

10.  Aqueous Extracts from Tunisian Diplotaxis: Phenol Content, Antioxidant and Anti-Acetylcholinesterase Activities, and Impact of Exposure to Simulated Gastrointestinal Fluids.

Authors:  Nada Bahloul; Sana Bellili; Smail Aazza; Ameur Chérif; Maria Leonor Faleiro; Maria Dulce Antunes; Maria Graça Miguel; Wissem Mnif
Journal:  Antioxidants (Basel)       Date:  2016-04-02
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