Literature DB >> 22082163

Targeting airway smooth muscle in airways diseases: an old concept with new twists.

Cynthia J Koziol-White1, Gautam Damera, Reynold A Panettieri.   

Abstract

Airway smooth muscle (ASM) manifests a hyper-responsive phenotype in airway disorders such as asthma. ASM also modulates immune responses by secreting mediators and expressing cell-surface molecules that promote recruitment of inflammatory cells to the lungs. The aim of the current article is to highlight therapeutics that may modulate ASM responses in airway disorders and exacerbations.

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Year:  2011        PMID： 22082163      PMCID： PMC3276206          DOI： 10.1586/ers.11.77

Source DB:  PubMed          Journal:  Expert Rev Respir Med        ISSN： 1747-6348            Impact factor:   3.772


  88 in total

1.  Effects of inhaled tumour necrosis factor alpha in subjects with mild asthma.

Authors:  P S Thomas; G Heywood
Journal:  Thorax       Date:  2002-09       Impact factor: 9.139

2.  Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism.

Authors:  Peter R A Johnson; Janette K Burgess; P Anne Underwood; Wendy Au; Maree H Poniris; Michael Tamm; Qi Ge; Michael Roth; Judith L Black
Journal:  J Allergy Clin Immunol       Date:  2004-04       Impact factor: 10.793

3.  Suppression of colds in human volunteers challenged with rhinovirus by a new synthetic drug (R61837).

Authors:  W al-Nakib; P G Higgins; G I Barrow; D A Tyrrell; K Andries; G Vanden Bussche; N Taylor; P A Janssen
Journal:  Antimicrob Agents Chemother       Date:  1989-04       Impact factor: 5.191

4.  Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study.

Authors:  Jonathan M Corne; Clare Marshall; Sandra Smith; Jacquie Schreiber; Gwendolyn Sanderson; Stephen T Holgate; Sebastian L Johnston
Journal:  Lancet       Date:  2002-03-09       Impact factor: 79.321

5.  Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: one year, double blind, randomised, comparative trial.

Authors:  Leif Bjermer; Hans Bisgaard; Jean Bousquet; Leonardo M Fabbri; Andrew P Greening; Tari Haahtela; Stephen T Holgate; Cesar Picado; Joris Menten; S Balachandra Dass; Jonathan A Leff; Peter G Polos
Journal:  BMJ       Date:  2003-10-18

6.  Signaling pathways regulating interleukin-13-stimulated chemokine release from airway smooth muscle.

Authors:  Qi Peng; Takeshi Matsuda; Stuart J Hirst
Journal:  Am J Respir Crit Care Med       Date:  2003-12-11       Impact factor: 21.405

7.  Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma.

Authors:  Ratko Djukanović; Susan J Wilson; Monica Kraft; Nizar N Jarjour; Mark Steel; K Fan Chung; Weibin Bao; Angel Fowler-Taylor; John Matthews; William W Busse; Stephen T Holgate; John V Fahy
Journal:  Am J Respir Crit Care Med       Date:  2004-06-01       Impact factor: 21.405

8.  The role of a soluble TNFalpha receptor fusion protein (etanercept) in corticosteroid refractory asthma: a double blind, randomised, placebo controlled trial.

Authors:  J B Morjaria; A J Chauhan; K S Babu; R Polosa; D E Davies; S T Holgate
Journal:  Thorax       Date:  2008-02-01       Impact factor: 9.139

9.  Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways.

Authors:  Ofir Bachar; Mikael Adner; Rolf Uddman; Lars-Olaf Cardell
Journal:  Eur J Immunol       Date:  2004-04       Impact factor: 5.532

10.  Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study.

Authors:  Tillie-Louise Hackett; Rebecca Holloway; Stephen T Holgate; Jane A Warner
Journal:  Respir Res       Date:  2008-05-29
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  6 in total

1.  Estrogen receptor beta signaling inhibits PDGF induced human airway smooth muscle proliferation.

Authors:  Nilesh Sudhakar Ambhore; Rathnavali Katragadda; Rama Satyanarayana Raju Kalidhindi; Michael A Thompson; Christina M Pabelick; Y S Prakash; Venkatachalem Sathish
Journal:  Mol Cell Endocrinol       Date:  2018-04-20       Impact factor: 4.102

Review 2.  Modulation of Bronchomotor Tone Pathways in Airway Smooth Muscle Function and Bronchomotor Tone in Asthma.

Authors:  Cynthia J Koziol-White; Reynold A Panettieri
Journal:  Clin Chest Med       Date:  2018-12-19       Impact factor: 2.878

3.  Differential estrogen-receptor activation regulates extracellular matrix deposition in human airway smooth muscle remodeling via NF-κB pathway.

Authors:  Nilesh Sudhakar Ambhore; Rama Satyanarayana Raju Kalidhindi; Christina M Pabelick; John R Hawse; Y S Prakash; Venkatachalem Sathish
Journal:  FASEB J       Date:  2019-10-22       Impact factor: 5.834

4.  The role of IgE-receptors in IgE-dependent airway smooth muscle cell remodelling.

Authors:  Michael Roth; Jun Zhong; Celine Zumkeller; Chong Teck S'ng; Stephanie Goulet; Michael Tamm
Journal:  PLoS One       Date:  2013-02-14       Impact factor: 3.240

5.  Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection.

Authors:  Magda S Jonczyk; Michelle Simon; Saumya Kumar; Vitor E Fernandes; Nicolas Sylvius; Ann-Marie Mallon; Paul Denny; Peter W Andrew
Journal:  PLoS One       Date:  2014-03-03       Impact factor: 3.240

6.  A core viral protein binds host nucleosomes to sequester immune danger signals.

Authors:  Daphne C Avgousti; Christin Herrmann; Katarzyna Kulej; Neha J Pancholi; Nikolina Sekulic; Joana Petrescu; Rosalynn C Molden; Daniel Blumenthal; Andrew J Paris; Emigdio D Reyes; Philomena Ostapchuk; Patrick Hearing; Steven H Seeholzer; G Scott Worthen; Ben E Black; Benjamin A Garcia; Matthew D Weitzman
Journal:  Nature       Date:  2016-06-29       Impact factor: 49.962
  6 in total

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