Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.

Literature DB >> 22081012

Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway.

Ivan V Rosado¹, Frédéric Langevin, Gerry P Crossan, Minoru Takata, Ketan J Patel.

Abstract

Metabolism is predicted to generate formaldehyde, a toxic, simple, reactive aldehyde that can damage DNA. Here we report a synthetic lethal interaction in avian cells between ADH5, encoding the main formaldehyde-detoxifying enzyme, and the Fanconi anemia (FA) DNA-repair pathway. These results define a fundamental role for the combined action of formaldehyde catabolism and DNA cross-link repair in vertebrate cell survival.

Entities: Chemical

Mesh：

Substances：

Year: 2011 PMID： 22081012 DOI： 10.1038/nsmb.2173

Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369

18 in total

Review 1. Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases.

Authors: Nima Mosammaparast; Yang Shi
Journal: Annu Rev Biochem Date: 2010 Impact factor: 23.643

2. SLX4, a coordinator of structure-specific endonucleases, is mutated in a new Fanconi anemia subtype.

Authors: Chantal Stoepker; Karolina Hain; Beatrice Schuster; Yvonne Hilhorst-Hofstee; Martin A Rooimans; Jurgen Steltenpool; Anneke B Oostra; Katharina Eirich; Elisabeth T Korthof; Aggie W M Nieuwint; Nicolaas G J Jaspers; Thomas Bettecken; Hans Joenje; Detlev Schindler; John Rouse; Johan P de Winter
Journal: Nat Genet Date: 2011-01-16 Impact factor: 38.330

3. Immunocytochemical and biochemical demonstration of formaldhyde dehydrogenase (class III alcohol dehydrogenase) in the nucleus.

Authors: F J Iborra; J Renau-Piqueras; M Portoles; M D Boleda; C Guerri; X Pares
Journal: J Histochem Cytochem Date: 1992-12 Impact factor: 2.479

Review 4. Finding the needle in the hay stack: hematopoietic stem cells in Fanconi anemia.

Authors: Lars U W Müller; David A Williams
Journal: Mutat Res Date: 2009-04-02 Impact factor: 2.433

5. Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.

Authors: Yuji Nomura; Noritaka Adachi; Hideki Koyama
Journal: Genes Cells Date: 2007-10 Impact factor: 1.891

Review 6. The genetic and molecular basis of Fanconi anemia.

Authors: Johan P de Winter; Hans Joenje
Journal: Mutat Res Date: 2008-11-14 Impact factor: 2.433

7. Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde.

Authors: John R Ridpath; Ayumi Nakamura; Keizo Tano; April M Luke; Eiichiro Sonoda; Hiroshi Arakawa; Jean-Marie Buerstedde; David A F Gillespie; Julian E Sale; Mitsuyoshi Yamazoe; Douglas K Bishop; Minoru Takata; Shunichi Takeda; Masami Watanabe; James A Swenberg; Jun Nakamura
Journal: Cancer Res Date: 2007-12-01 Impact factor: 12.701

8. Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia.

Authors: Gerry P Crossan; Louise van der Weyden; Ivan V Rosado; Frederic Langevin; Pierre-Henri L Gaillard; Rebecca E McIntyre; Ferdia Gallagher; Mikko I Kettunen; David Y Lewis; Kevin Brindle; Mark J Arends; David J Adams; Ketan J Patel
Journal: Nat Genet Date: 2011-01-16 Impact factor: 38.330

9. Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum.

Authors: Xiao-Yin Zhang; Judith Langenick; David Traynor; M Madan Babu; Rob R Kay; Ketan J Patel
Journal: PLoS Genet Date: 2009-09-18 Impact factor: 5.917

Review 10. Fanconi anemia and DNA replication repair.

Authors: Ketan J Patel; Hans Joenje
Journal: DNA Repair (Amst) Date: 2007-05-03

97 in total

1. ICLs: a chicken without an egg.

Authors: Simon Bekker-Jensen; Niels Mailand
Journal: Nat Rev Mol Cell Biol Date: 2012-04-25 Impact factor: 94.444

Review 2. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway.

Authors: Hyungjin Kim; Alan D D'Andrea
Journal: Genes Dev Date: 2012-07-01 Impact factor: 11.361

3. S-phase sensing of DNA-protein crosslinks triggers TopBP1-independent ATR activation and p53-mediated cell death by formaldehyde.

Authors: Victor Chun-Lam Wong; Haley L Cash; Jessica L Morse; Shan Lu; Anatoly Zhitkovich
Journal: Cell Cycle Date: 2012-07-01 Impact factor: 4.534

4. DNA crosslinking damage and cancer - a tale of friend and foe.

Authors: Yaling Huang; Lei Li
Journal: Transl Cancer Res Date: 2013-06 Impact factor: 1.241

5. Formation, Accumulation, and Hydrolysis of Endogenous and Exogenous Formaldehyde-Induced DNA Damage.

Authors: Rui Yu; Yongquan Lai; Hadley J Hartwell; Benjamin C Moeller; Melanie Doyle-Eisele; Dean Kracko; Wanda M Bodnar; Thomas B Starr; James A Swenberg
Journal: Toxicol Sci Date: 2015-04-21 Impact factor: 4.849

6. Formaldehyde Is a Potent Proteotoxic Stressor Causing Rapid Heat Shock Transcription Factor 1 Activation and Lys48-Linked Polyubiquitination of Proteins.

Authors: Sara Ortega-Atienza; Blazej Rubis; Caitlin McCarthy; Anatoly Zhitkovich
Journal: Am J Pathol Date: 2016-09-14 Impact factor: 4.307

7. Hypersensitivities for acetaldehyde and other agents among cancer cells null for clinically relevant Fanconi anemia genes.

Authors: Soma Ghosh; Surojit Sur; Sashidhar R Yerram; Carlo Rago; Anil K Bhunia; M Zulfiquer Hossain; Bogdan C Paun; Yunzhao R Ren; Christine A Iacobuzio-Donahue; Nilofer A Azad; Scott E Kern
Journal: Am J Pathol Date: 2013-11-06 Impact factor: 4.307