Literature DB >> 2208090

Increased biopterin production in rats with tumors induced by radon inhalation and benzonaphthoflavone administration.

P Mura1, J P Morlier, M Barriere, P Bredon, Y Papet, J Chameaud.   

Abstract

Serial determinations of urinary biopterin were performed in rats during the development of lung tumors induced by radon inhalation and 5,6-benzonaphtoflavone administration. A striking increase in biopterin levels was observed in animals which developed single or multiple epidermoid carcinoma of the lung and this increase occurred several weeks before tumors could be detected radiographically.

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Year:  1990        PMID: 2208090     DOI: 10.1016/0304-3835(90)90091-b

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  1 in total

1.  Impact of tumour necrosis factor-alpha and interferon-gamma on tetrahydrobiopterin synthesis in murine fibroblasts and macrophages.

Authors:  E R Werner; G Werner-Felmayer; D Fuchs; A Hausen; G Reibnegger; J J Yim; H Wachter
Journal:  Biochem J       Date:  1991-12-15       Impact factor: 3.857

  1 in total

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